Exact Mass: 754.2534

Exact Mass Matches: 754.2534

Found 1 metabolites which its exact mass value is equals to given mass value 754.2534, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

ADH-6 (TFA)

ADH-6 (TFA)

C31H37F3N8O11 (754.2534)


ADH-6 TFA is a tripyridylamide compound. ADH-6 abrogates self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD. ADH-6 TFA targets and dissociates mutant p53 aggregates in human cancer cells, which restores p53's transcriptional activity, leading to cell cycle arrest and apoptosis. ADH-6 TFA has the potential for the research of cancer diseases[1].