Exact Mass: 695.1212950000001
Exact Mass Matches: 695.1212950000001
Found 1 metabolites which its exact mass value is equals to given mass value 695.1212950000001,
within given mass tolerance error 3.2E-7 dalton. Try search metabolite list with more accurate mass tolerance error
6.4E-8 dalton.
MI-1061 (TFA)
MI-1061 (TFA)
C32H27Cl2F4N3O6 (695.1212950000001)
MI-1061 TFA is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 TFA potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].