Exact Mass: 695.1212950000001
Exact Mass Matches: 695.1212950000001
Found 1 metabolites which its exact mass value is equals to given mass value 695.1212950000001,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
MI-1061 (TFA)
MI-1061 (TFA)
C32H27Cl2F4N3O6 (695.1212950000001)
MI-1061 TFA is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 TFA potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].