Exact Mass: 615.0978852000001
Exact Mass Matches: 615.0978852000001
Found 15 metabolites which its exact mass value is equals to given mass value 615.0978852000001,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Trametinib
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01E - Protein kinase inhibitors > L01EE - Mitogen-activated protein kinase (mek) inhibitors C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C69145 - Mitogen-Activated Protein Kinase Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor D004791 - Enzyme Inhibitors > D047428 - Protein Kinase Inhibitors C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor D000970 - Antineoplastic Agents Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis[1][2].
N-(3-(3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-diMethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyriMidin-5-ylaMino)phenyl)acetaMide
Dabrafenib Mesylate
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C61074 - Serine/Threonine Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2336 - Raf Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively.
4-Chloro-N-{[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl}-N-(4-methoxyphenyl)benzohydrazide
GDP-4-oxo,6-deoxy-D-lyxo-heptose
C17H23N5O16P2-2 (615.0615018000001)
GDP-6-deoxy-4-keto-L-xylo-heptose
C17H23N5O16P2-2 (615.0615018000001)
GDP-6-deoxy-4-keto-L-ribo-heptose
C17H23N5O16P2-2 (615.0615018000001)
GDP-6-deoxy-4-keto-D-arabino-heptose
C17H23N5O16P2-2 (615.0615018000001)
[4-[6-Benzyl-5-[[4-oxo-3-[(4-sulfooxyphenyl)methyl]dioxetan-3-yl]amino]pyrazin-2-yl]phenyl] hydrogen sulfate
C26H21N3O11S2 (615.0617476000001)
Lamellarin alpha 20-sulfate
C29H22NNaO11S (615.0811222000001)
An organic sodium salt of lamellarin alpha 20-hydrogen sulfate. It is isolated from an unidentified ascidian (IIC-197) and exhibits inhibitory activity against HIV-1 integrase.
[(2R,3S,4R)-2-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxymethyl]-4,5-dihydroxyoxolan-3-yl] propanoate
C18H27N5O15P2 (615.0978852000001)