Exact Mass: 612.2366
Exact Mass Matches: 612.2366
Found 95 metabolites which its exact mass value is equals to given mass value 612.2366
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Novobiocin
Novobiocin is only found in individuals that have used or taken this drug. It is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase, and blocks adenosine triphosphatase (ATPase) activity. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) [PubChem]Novobiocin is an aminocoumarin. Aminocoumarins are very potent inhibitors of bacterial DNA gyrase and work by inhibiting the GyrB subunit of the enzyme involved in energy tranduction. Novobiocin as well as the other aminocoumarin antibiotics act as competitive inhibitors of the ATPase reaction catalysed by GyrB. D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents C254 - Anti-Infective Agent > C258 - Antibiotic CONFIDENCE standard compound; INTERNAL_ID 1168 CONFIDENCE standard compound; INTERNAL_ID 1167 Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity[1][2][3][4][6].
cyclic RGD
GalNAcFucGlcNAcGA-I
[Chemical] Source; sea squirt H-antigen (limited periodate oxide)
GalNAcFucGlcNAcGA-II
[Chemical] Source; sea squirt H-antigen (limited periodate oxide)
(7S,8S,7?S,8?R)-4,9,4?-trihydroxy-3,5,3?,5?,7?-pentamethoxy-7,9?-epoxylignan 9-O-beta-D-glucopyranoside|ligalbumoside B
9-(beta-D-glucopyranosyloxy)-3,5,3,5 -tetramethoxy-7,9-epoxylignane-4,4,7-triol|pseuderanoside
nagilactone A 7-O-alpha-L-arabinopyranosyl-(1->4)-beta-D-xylopyranoside
2-carbomethoxy-3-prenyl-1,4-naphthoquinone-1,4-di-O-beta-D-glucopyranoside
Novobiocin
D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents A coumarin-derived antibiotic obtained from Streptomyces niveus. C254 - Anti-Infective Agent > C258 - Antibiotic Origin: Microbe, Coumarins Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity[1][2][3][4][6].