Exact Mass: 606.273
Exact Mass Matches: 606.273
Found 126 metabolites which its exact mass value is equals to given mass value 606.273
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within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Cepharanthine
Cepharanthine is a bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation. It is a member of isoquinolines and a bisbenzylisoquinoline alkaloid. Cepharanthine is a natural product found in Stephania sinica, Stephania cephalantha, and other organisms with data available. A bisbenzylisoquinoline alkaloid from tubers of Stephania; stimulates recovery of immunologic function in lymphatic system after administration of antineoplastic agents or x-irradiation. C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D020011 - Protective Agents > D011837 - Radiation-Protective Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D000970 - Antineoplastic Agents D018501 - Antirheumatic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Origin: Plant; SubCategory_DNP: Isoquinoline alkaloids, Benzylisoquinoline alkaloids Cepharanthine is a natural product that can be isolated from the plant Stephania?cephalantha?Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50\\%) inhibitory concentration (IC50) and 90\\% inhibitory concentration (IC90) values of 1.90 and 4.46?μM[1]. Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model[2][3]. Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects[4][5][6][7][8]. Cepharanthine is a natural product that can be isolated from the plant Stephania?cephalantha?Hayata. Cepharanthine has anti-severe acute respiratory syndrome coronavirus 2 (anti-SARS-CoV-2) activities. Cepharanthine has good effective in suppressing viral proliferation (half maximal (50\%) inhibitory concentration (IC50) and 90\% inhibitory concentration (IC90) values of 1.90 and 4.46?μM[1]. Cepharanthine can also effectively reverses P-gp-mediated multidrug resistance in K562 cells and increase enhances the sensitivity of anticancer agents in xenograft mice model[2][3]. Cepharanthine shows inhibitory effects of human liver cytochrome P450 enzymes CYP3A4, CYP2E1 and CYP2C9. Cepharanthine has antitumor, anti-inflammatory and antinociceptive effects[4][5][6][7][8].
Cepharanthine
[(1R,3R,5S,7S,8S,9R,10R)-7,9,10-triacetyloxy-8,12,15,15-tetramethyl-4-methylidene-13-oxo-5-tricyclo[9.3.1.0^{3,8]pentadec-11-enyl] (E)-3-phenylprop-2-enoate
2alpha,4alpha,7beta,9alpha,1alpha,15-hexahydroxy-5alpha,20-diacetoxy-10beta-benzoxy-11(15->1)abeotaxa-11-ene|taxuyunnanine U
3beta,5alpha,8alpha,15beta-tetraacetoxy-7beta-propionyloxyjatropha-6(17),11E-diene-4,14-dione
6,12-dimethoxy-2,2-dimethyl-6,8alpha-(1-oxa-ethane-1,2-diyl)-8H-berbaman-7-one|Pseudorepandulin|pseudorepanduline
(1S,4R,5S,6R,7R,8R,9S,10S)-6-acetoxy-1,9-dibenzoyloxy-8-butyryloxydihydro-beta-agarofuran
5alpha-cinnamoyloxy-2alpha,10beta,13alpha-triacetoxy-2(3->2)abeo-taxa-4(20),11-dien-9-one
(1R,2S,4S,5S,6R,7R,8S,9S,10S)-1,2-diacetoxy-9-benzoyloxy-15-(2-methylbutyroyloxy)-4,6,8-trihydroxydihydro-beta-agarofuran
Taxinin
Taxinine is a natural product found in Taxus wallichiana, Taxus baccata, and other organisms with data available.
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N-[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[oxo-[4-(trifluoromethyl)anilino]methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-oxanecarboxamide
N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[oxo-[4-(trifluoromethyl)anilino]methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-oxanecarboxamide
N-[(2R,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[oxo-[4-(trifluoromethyl)anilino]methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-oxanecarboxamide
N-[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[oxo-[4-(trifluoromethyl)anilino]methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-4-oxanecarboxamide
(1r,8r,10r)-2,9,10-tris(acetyloxy)-8,12,15,15-tetramethyl-4-methylidene-13-oxotricyclo[9.3.1.0³,⁸]pentadec-11-en-5-yl (2e)-3-phenylprop-2-enoate
(3s,3ar,4s,6s,7s,8s)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2z)-2-methylbut-2-enoyl]oxy}-2-oxo-4h,5h,6ah,7h,8h,9bh-azuleno[4,5-b]furan-7-yl (2z)-2-methylbut-2-enoate
(1r,3r,5s,7s,8s,9r,10r)-7,9,10-tris(acetyloxy)-8,12,15,15-tetramethyl-4-methylidene-13-oxotricyclo[9.3.1.0³,⁸]pentadec-11-en-5-yl (2e)-3-phenylprop-2-enoate
(1r,3r,5r,6as,7r,8r,10s,10as)-1,3,5-tris(acetyloxy)-7,8-dimethyl-7-(3-methylidenepent-4-en-1-yl)-1h,3h,5h,6h,6ah,8h,9h,10h-naphtho[1,8a-c]furan-10-yl (2e)-3-phenylprop-2-enoate
2,10,13-tris(acetyloxy)-8,12,15,15-tetramethyl-9-oxotricyclo[9.3.1.1⁴,⁸]hexadeca-3,11-dien-5-yl 3-phenylprop-2-enoate
(1s,3s,5s,6ar,7s,8s,10r,10ar)-1,3,5-tris(acetyloxy)-7,8-dimethyl-7-[(2e)-3-methylpenta-2,4-dien-1-yl]-1h,3h,5h,6h,6ah,8h,9h,10h-naphtho[1,8a-c]furan-10-yl (2e)-3-phenylprop-2-enoate
17-(acetyloxy)-8-(furan-3-yl)-4,19-dihydroxy-1,9,11,16-tetramethyl-5,14-dioxapentacyclo[11.6.1.0²,¹¹.0⁶,¹⁰.0¹⁶,²⁰]icos-9-en-12-yl benzoate
1-deacetylnimbolinin a
{"Ingredient_id": "HBIN002467","Ingredient_name": "1-deacetylnimbolinin a","Alias": "NA","Ingredient_formula": "C35H42O9","Ingredient_Smile": "CC1=C2C(CC1C3=COC=C3)OC(CC4C2(C(C5C6C4(C(CC(C6(CO5)C)OC(=O)C)O)C)OC(=O)C7=CC=CC=C7)C)O","Ingredient_weight": "606.7 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "4754","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "100945036","DrugBank_id": "NA"}
1- o -deacetylnimbolinin a
{"Ingredient_id": "HBIN002895","Ingredient_name": "1- o -deacetylnimbolinin a","Alias": "NA","Ingredient_formula": "C35H42O9","Ingredient_Smile": "NA","Ingredient_weight": "606.711","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "9732","PubChem_id": "NA","DrugBank_id": "NA"}
ajugacumbin e
{"Ingredient_id": "HBIN014965","Ingredient_name": "ajugacumbin e","Alias": "NA","Ingredient_formula": "C31H42O12","Ingredient_Smile": "CC1CC(C2(C(C1(C)CCC3=CC(=O)OC3)C(CC(C24CO4)OC(=O)C)OC(=O)C)COC(=O)C(=C)C(C)O)OC(=O)C","Ingredient_weight": "606.7 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "SMIT14204","TCMID_id": "792","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "14781375","DrugBank_id": "NA"}