Exact Mass: 578.2193
Exact Mass Matches: 578.2193
Found 167 metabolites which its exact mass value is equals to given mass value 578.2193
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
gosspyl acetate
R-(-)-Gossypol Acetic Acid is the orally bioavailable solvate of the R-(-) enantiomer of gossypol and acetic acid with potential antineoplastic activity. As a BH3 mimetic, R-(-)-gossypol binds to the hydrophobic surface binding groove BH3 of the anti-apoptotic proteins Bcl-2 and Bcl-xL, blocking their heterodimerization with pro-apoptotic members of the Bcl-2 family of proteins such as Bad, Bid, and Bim; this may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Racemic gossypol is a polyphenolic compound isolated from cottonseed. Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.
(1S,4aS,6R,9S,9aS)-7-{2-[(3R)-2,3-dihydro-3-hydroxy-2-oxo-1H-indol-3-yl]ethyl}-1-(beta-D-glucopyranosyloxy)-1,4a,5,6,7,8,9,9a-octahydro-6,9-epoxypyrano[3,4-d]azepine-4-carboxylic acid methyl ester|anthocephalusine A
(aR)-3,3-Dimethyl-7,7,9,9-tetramethoxy-3,3,4,4-tetrahydro-5,6-bi[1H-naphtho[2,3-c]pyran]-4,4,10,10-tetraol
phenethyl alcohol 8-O-beta-D-glucopyranosyl-(1->2)-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside
kansanoside A|phenylethyl-beta-D-glucopyranosyl-(1->2)-[beta-D-xylopyranosyl-(1->6)]-beta-D-galactopyranoside
gosspyl acetate
R-(-)-Gossypol Acetic Acid is the orally bioavailable solvate of the R-(-) enantiomer of gossypol and acetic acid with potential antineoplastic activity. As a BH3 mimetic, R-(-)-gossypol binds to the hydrophobic surface binding groove BH3 of the anti-apoptotic proteins Bcl-2 and Bcl-xL, blocking their heterodimerization with pro-apoptotic members of the Bcl-2 family of proteins such as Bad, Bid, and Bim; this may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Racemic gossypol is a polyphenolic compound isolated from cottonseed. Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. Gossypol acetic acid ((±)-Gossypol-acetic acid) binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively.
(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol
(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol
(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol [IIN-based on: CCMSLIB00000849079]
(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol [IIN-based: Match]
(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol_major
(3S,4S)-5-[(3S,4S)-4,10-dihydroxy-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromen-5-yl]-7,9-dimethoxy-3-methyl-3,4-dihydro-1H-benzo[g]isochromene-4,10-diol_67.3\\%
Cys Asp Arg Trp
Cys Asp Trp Arg
Cys Phe Phe Tyr
Cys Phe Tyr Phe
Cys Arg Asp Trp
Cys Arg Trp Asp
Cys Trp Asp Arg
Cys Trp Arg Asp
Cys Tyr Phe Phe
Asp Cys Arg Trp
Asp Cys Trp Arg
Asp Met Gln Trp
Asp Met Trp Gln
Asp Gln Met Trp
Asp Gln Trp Met
Asp Arg Cys Trp
Asp Arg Trp Cys
Asp Trp Cys Arg
Asp Trp Met Gln
Asp Trp Gln Met
Asp Trp Arg Cys
Glu His Met Tyr
Glu His Tyr Met
Glu Met His Tyr
Glu Met Asn Trp
Glu Met Trp Asn
Glu Met Tyr His
Glu Asn Met Trp
Glu Asn Trp Met
Glu Trp Met Asn
Glu Trp Asn Met
Glu Tyr His Met
Glu Tyr Met His
Phe Cys Phe Tyr
Phe Cys Tyr Phe
Phe Phe Cys Tyr
Phe Phe Tyr Cys
Phe Tyr Cys Phe
Phe Tyr Phe Cys
His Glu Met Tyr
His Glu Tyr Met
His Met Glu Tyr
His Met Tyr Glu
His Tyr Glu Met
His Tyr Met Glu
Met Asp Gln Trp
Met Asp Trp Gln
Met Glu His Tyr
Met Glu Asn Trp
Met Glu Trp Asn
Met Glu Tyr His
Met His Glu Tyr
Met His Tyr Glu
Met Asn Glu Trp
Met Asn Trp Glu
Met Gln Asp Trp
Met Gln Trp Asp
Met Trp Asp Gln
Met Trp Glu Asn
Met Trp Asn Glu
Met Trp Gln Asp
Met Tyr Glu His
Met Tyr His Glu
Asn Glu Met Trp
Asn Glu Trp Met
Asn Met Glu Trp
Asn Met Trp Glu
Asn Trp Glu Met
Asn Trp Met Glu
Gln Asp Met Trp
Gln Asp Trp Met
Gln Met Asp Trp
Gln Met Trp Asp
Gln Trp Asp Met
Gln Trp Met Asp
Arg Cys Asp Trp
Arg Cys Trp Asp
Arg Asp Cys Trp
Arg Asp Trp Cys
Arg Trp Cys Asp
Arg Trp Asp Cys
Trp Cys Asp Arg
Trp Cys Arg Asp
Trp Asp Cys Arg
Trp Asp Met Gln
Trp Asp Gln Met
Trp Asp Arg Cys
Trp Glu Met Asn
Trp Glu Asn Met
Trp Met Asp Gln
Trp Met Glu Asn
Trp Met Asn Glu
Trp Met Gln Asp
Trp Asn Glu Met
Trp Asn Met Glu
Trp Gln Asp Met
Trp Gln Met Asp
Trp Arg Cys Asp
Trp Arg Asp Cys
Tyr Cys Phe Phe
Tyr Glu His Met
Tyr Glu Met His
Tyr Phe Cys Phe
Tyr Phe Phe Cys
Tyr His Glu Met
Tyr His Met Glu
Tyr Met Glu His
Tyr Met His Glu
Vardenafil HCl Trihydrate
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058986 - Phosphodiesterase 5 Inhibitors C471 - Enzyme Inhibitor > C744 - Phosphodiesterase Inhibitor > C2127 - cGMP Phosphodiesterase Inhibitor D000089162 - Genitourinary Agents > D064804 - Urological Agents D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
Ananolignan K
A lignan with a dibenzocyclooctadiene skeleton isolated from Kadsura ananosma
N-[[(4S,5R)-8-(1-cyclohexenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
N-[[(4R,5R)-8-(1-cyclohexenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
N-[[(4S,5S)-8-(1-cyclohexenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
N-[[(4S,5R)-8-(1-cyclohexenyl)-2-[(2S)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
N-[[(4R,5R)-8-(1-cyclohexenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
N-[[(4R,5S)-8-(1-cyclohexenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
2-[(2R,4aR,12aS)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
N-[[(4S,5S)-8-(1-cyclohexenyl)-2-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,1-dioxo-4,5-dihydro-3H-6,1$l^{6},2-benzoxathiazocin-5-yl]methyl]-3-methoxy-N-methylbenzenesulfonamide
2-[(2S,4aR,12aR)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
2-[(2R,4aS,12aR)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
2-[(2S,4aS,12aS)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
2-[(2S,4aS,12aR)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
2-[(2S,4aR,12aS)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
2-[(2R,4aR,12aR)-5-methyl-8-[(4-methylphenyl)sulfonylamino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2-pyridin-4-ylethyl)acetamide
Cyclo(Arg-Gly-Asp-D-Phe-Cys)
Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].