Exact Mass: 552.1888

Exact Mass Matches: 552.1888

Found 2 metabolites which its exact mass value is equals to given mass value 552.1888, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Allisartan isoproxil

{[(propan-2-yloxy)carbonyl]oxy}methyl 2-butyl-4-chloro-1-{[2-(2H-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylate

C27H29ClN6O5 (552.1888)


Allisartan isoproxil (ALS-3) is an orally potent, selective, non-peptide inhibitor of Angiotensin II Type 1. Allisartan isoproxil is also an antihypertensive agent. Allisartan isoproxil may inhibit angiotensin-aldosterone system and oxidative stress. Allisartan isoproxil lowers blood pressure and protects the organs, preventing cerebrovascular damage. Allisartan isoproxil (80-320 mg/kg/d) has shown toxicity in rat models by targeting liver organs[1][2].