Exact Mass: 551.2591
Exact Mass Matches: 551.2591
Found 500 metabolites which its exact mass value is equals to given mass value 551.2591
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Endoxifen O-glucuronide
Endoxifen O-glucuronide is a metabolite of tamoxifen. Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. In other tissues such as the endometrium, it behaves as an agonist, and thus may be characterized as a mixed agonist/antagonist. Tamoxifen is the usual endocrine therapy for hormone receptor-positive breast cancer in pre-menopausal women, and is also a standard in post-menopausal women although aromatase inhibitors are also frequently used in that setting. (Wikipedia)
Akt inhibitor VIII
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
2,6-Bis(2-phenylethyl)-3,5-bis(3-phenylpropanoyl)pyridine
Arg Phe Thr Glu
Phe Arg Thr Glu
Phe Asp Arg Asp
Tyr Arg Val Asp
Thr Arg Phe Glu
Val Tyr Asp Arg
Glu Thr Phe Arg
Gln Ile Tyr Glu
Ala Glu Phe Trp
Ala Glu Trp Phe
Ala Phe Glu Trp
Ala Phe Trp Glu
Ala Ile Trp Tyr
Ala Ile Tyr Trp
Ala Leu Trp Tyr
Ala Leu Tyr Trp
Ala Trp Glu Phe
Ala Trp Phe Glu
Ala Trp Ile Tyr
Ala Trp Leu Tyr
Ala Trp Tyr Ile
Ala Trp Tyr Leu
Ala Tyr Ile Trp
Ala Tyr Leu Trp
Ala Tyr Trp Ile
Ala Tyr Trp Leu
Cys His His Arg
Cys His Arg His
Cys Arg His His
Asp Asp Phe Arg
Asp Asp Arg Phe
Asp Phe Asp Arg
Asp Phe Arg Asp
Asp Arg Asp Phe
Asp Arg Phe Asp
Asp Arg Val Tyr
Asp Arg Tyr Val
Asp Val Arg Tyr
Asp Val Tyr Arg
Asp Tyr Arg Val
Asp Tyr Val Arg
Glu Ala Phe Trp
Glu Ala Trp Phe
Glu Glu Phe Lys
Glu Glu Lys Phe
Glu Phe Ala Trp
Glu Phe Glu Lys
Glu Phe Lys Glu
Glu Phe Arg Thr
Glu Phe Thr Arg
Glu Phe Trp Ala
Glu Ile Gln Tyr
Glu Ile Tyr Gln
Glu Lys Glu Phe
Glu Lys Phe Glu
Glu Leu Gln Tyr
Glu Leu Tyr Gln
Glu Gln Ile Tyr
Glu Gln Leu Tyr
Glu Gln Tyr Ile
Glu Gln Tyr Leu
Glu Arg Phe Thr
Glu Arg Thr Phe
Glu Thr Arg Phe
Glu Trp Ala Phe
Glu Trp Phe Ala
Glu Tyr Ile Gln
Glu Tyr Leu Gln
Glu Tyr Gln Ile
Glu Tyr Gln Leu
Phe Ala Glu Trp
Phe Ala Trp Glu
Phe Asp Asp Arg
Phe Glu Ala Trp
Phe Glu Glu Lys
Phe Glu Lys Glu
Phe Glu Arg Thr
Phe Glu Thr Arg
Phe Glu Trp Ala
Phe Ile Ser Trp
Phe Ile Trp Ser
Phe Lys Glu Glu
Phe Leu Ser Trp
Phe Leu Trp Ser
Phe Met Arg Val
Phe Met Val Arg
Phe Arg Asp Asp
Phe Arg Glu Thr
Phe Arg Met Val
Phe Arg Val Met
Phe Ser Ile Trp
Phe Ser Leu Trp
Phe Ser Trp Ile
Phe Ser Trp Leu
Phe Thr Glu Arg
Phe Thr Arg Glu
Phe Thr Val Trp
Phe Thr Trp Val
Phe Val Met Arg
Phe Val Arg Met
Phe Val Thr Trp
Phe Val Trp Thr
Phe Trp Ala Glu
Phe Trp Glu Ala
Phe Trp Ile Ser
Phe Trp Leu Ser
Phe Trp Ser Ile
Phe Trp Ser Leu
Phe Trp Thr Val
Phe Trp Val Thr
His Cys His Arg
His Cys Arg His
His His Cys Arg
His His Lys Met
His His Met Lys
His His Arg Cys
His Ile Pro Trp
His Ile Trp Pro
His Lys His Met
His Lys Met His
His Leu Pro Trp
His Leu Trp Pro
His Met His Lys
His Met Lys His
His Pro Ile Trp
His Pro Leu Trp
His Pro Trp Ile
His Pro Trp Leu
His Arg Cys His
His Arg His Cys
His Trp Ile Pro
His Trp Leu Pro
His Trp Pro Ile
His Trp Pro Leu
Ile Ala Trp Tyr
Ile Ala Tyr Trp
Ile Glu Gln Tyr
Ile Glu Tyr Gln
Ile Phe Ser Trp
Ile Phe Trp Ser
Ile His Pro Trp
Ile His Trp Pro
Ile Pro His Trp
Ile Pro Trp His
Ile Gln Glu Tyr
Ile Gln Tyr Glu
Ile Ser Phe Trp
Ile Ser Trp Phe
Ile Trp Ala Tyr
Ile Trp Phe Ser
Ile Trp His Pro
Ile Trp Pro His
Ile Trp Ser Phe
Ile Trp Tyr Ala
Ile Tyr Ala Trp
Ile Tyr Glu Gln
Ile Tyr Gln Glu
Ile Tyr Trp Ala
Lys Glu Glu Phe
Lys Glu Phe Glu
Lys Phe Glu Glu
Lys His His Met
Lys His Met His
Lys Met His His
Lys Asn Gln Tyr
Lys Asn Tyr Gln
Lys Gln Asn Tyr
Lys Gln Tyr Asn
Lys Tyr Asn Gln
Lys Tyr Gln Asn
Leu Ala Trp Tyr
Leu Ala Tyr Trp
Leu Glu Gln Tyr
Leu Glu Tyr Gln
Leu Phe Ser Trp
Leu Phe Trp Ser
Leu His Pro Trp
Leu His Trp Pro
Leu Pro His Trp
Leu Pro Trp His
Leu Gln Glu Tyr
Leu Gln Tyr Glu
Leu Ser Phe Trp
Leu Ser Trp Phe
Leu Trp Ala Tyr
Leu Trp Phe Ser
Leu Trp His Pro
Leu Trp Pro His
Leu Trp Ser Phe
Leu Trp Tyr Ala
Leu Tyr Ala Trp
Leu Tyr Glu Gln
Leu Tyr Gln Glu
Leu Tyr Trp Ala
Met Phe Arg Val
Met Phe Val Arg
Met His His Lys
Met His Lys His
Met Lys His His
Met Arg Phe Val
Asn Lys Gln Tyr
Asn Lys Tyr Gln
Asn Gln Lys Tyr
Asn Gln Gln Tyr
Asn Gln Tyr Lys
Asn Gln Tyr Gln
Asn Tyr Lys Gln
Asn Tyr Gln Lys
Asn Tyr Gln Gln
Pro His Ile Trp
Pro His Leu Trp
Pro His Trp Ile
Pro His Trp Leu
Pro Ile His Trp
Pro Ile Trp His
Pro Leu His Trp
Pro Leu Trp His
Pro Ser Trp Tyr
Pro Ser Tyr Trp
Pro Trp His Ile
Pro Trp His Leu
Pro Trp Ile His
Pro Trp Leu His
Pro Trp Ser Tyr
Pro Trp Tyr Ser
Pro Tyr Ser Trp
Pro Tyr Trp Ser
Gln Glu Ile Tyr
Gln Glu Leu Tyr
Gln Glu Tyr Ile
Gln Glu Tyr Leu
Gln Ile Glu Tyr
Gln Lys Asn Tyr
Gln Lys Tyr Asn
Gln Leu Glu Tyr
Gln Leu Tyr Glu
Gln Asn Lys Tyr
Gln Asn Gln Tyr
Gln Asn Tyr Lys
Gln Asn Tyr Gln
Gln Gln Asn Tyr
Gln Gln Tyr Asn
Gln Tyr Glu Ile
Gln Tyr Glu Leu
Gln Tyr Ile Glu
Gln Tyr Lys Asn
Gln Tyr Leu Glu
Gln Tyr Asn Lys
Gln Tyr Asn Gln
Gln Tyr Gln Asn
Arg Cys His His
Arg Asp Asp Phe
Arg Asp Phe Asp
Arg Asp Val Tyr
Arg Asp Tyr Val
Arg Glu Phe Thr
Arg Glu Thr Phe
Arg Phe Asp Asp
Arg Phe Glu Thr
Arg His Cys His
Arg His His Cys
Arg Thr Glu Phe
Arg Thr Phe Glu
Arg Val Asp Tyr
Arg Val Tyr Asp
Arg Tyr Asp Val
Arg Tyr Val Asp
Ser Phe Ile Trp
Ser Phe Leu Trp
Ser Phe Trp Ile
Ser Phe Trp Leu
Ser Ile Phe Trp
Ser Ile Trp Phe
Ser Leu Phe Trp
Ser Leu Trp Phe
Ser Pro Trp Tyr
Ser Pro Tyr Trp
Ser Trp Phe Ile
Ser Trp Phe Leu
Ser Trp Ile Phe
Ser Trp Leu Phe
Ser Trp Pro Tyr
Ser Trp Tyr Pro
Ser Tyr Pro Trp
Ser Tyr Trp Pro
Thr Glu Phe Arg
Thr Glu Arg Phe
Thr Phe Glu Arg
Thr Phe Arg Glu
Thr Phe Val Trp
Thr Phe Trp Val
Thr Arg Glu Phe
Thr Val Phe Trp
Thr Val Trp Phe
Thr Trp Phe Val
Thr Trp Val Phe
Val Asp Arg Tyr
Val Asp Tyr Arg
Val Phe Thr Trp
Val Phe Trp Thr
Val Arg Asp Tyr
Val Arg Tyr Asp
Val Thr Phe Trp
Val Thr Trp Phe
Val Trp Phe Thr
Val Trp Thr Phe
Val Tyr Arg Asp
Trp Ala Glu Phe
Trp Ala Phe Glu
Trp Ala Ile Tyr
Trp Ala Leu Tyr
Trp Ala Tyr Ile
Trp Ala Tyr Leu
Trp Glu Ala Phe
Trp Glu Phe Ala
Trp Phe Ala Glu
Trp Phe Glu Ala
Trp Phe Ile Ser
Trp Phe Leu Ser
Trp Phe Ser Ile
Trp Phe Ser Leu
Trp Phe Thr Val
Trp Phe Val Thr
Trp His Ile Pro
Trp His Leu Pro
Trp His Pro Ile
Trp His Pro Leu
Trp Ile Ala Tyr
Trp Ile Phe Ser
Trp Ile His Pro
Trp Ile Pro His
Trp Ile Ser Phe
Trp Ile Tyr Ala
Trp Leu Ala Tyr
Trp Leu Phe Ser
Trp Leu His Pro
Trp Leu Pro His
Trp Leu Ser Phe
Trp Leu Tyr Ala
Trp Pro His Ile
Trp Pro His Leu
Trp Pro Ile His
Trp Pro Leu His
Trp Pro Ser Tyr
Trp Pro Tyr Ser
Trp Ser Phe Ile
Trp Ser Phe Leu
Trp Ser Ile Phe
Trp Ser Leu Phe
Trp Ser Pro Tyr
Trp Ser Tyr Pro
Trp Thr Phe Val
Trp Thr Val Phe
Trp Val Phe Thr
Trp Val Thr Phe
Trp Tyr Ala Ile
Trp Tyr Ala Leu
Trp Tyr Ile Ala
Trp Tyr Leu Ala
Trp Tyr Pro Ser
Trp Tyr Ser Pro
Tyr Ala Ile Trp
Tyr Ala Leu Trp
Tyr Ala Trp Ile
Tyr Ala Trp Leu
Tyr Asp Arg Val
Tyr Asp Val Arg
Tyr Glu Ile Gln
Tyr Glu Leu Gln
Tyr Glu Gln Ile
Tyr Glu Gln Leu
Tyr Ile Ala Trp
Tyr Ile Glu Gln
Tyr Ile Gln Glu
Tyr Ile Trp Ala
Tyr Lys Asn Gln
Tyr Lys Gln Asn
Tyr Leu Ala Trp
Tyr Leu Glu Gln
Tyr Leu Gln Glu
Tyr Leu Trp Ala
Tyr Asn Lys Gln
Tyr Asn Gln Lys
Tyr Asn Gln Gln
Tyr Pro Ser Trp
Tyr Pro Trp Ser
Tyr Gln Glu Ile
Tyr Gln Glu Leu
Tyr Gln Ile Glu
Tyr Gln Lys Asn
Tyr Gln Leu Glu
Tyr Gln Asn Lys
Tyr Gln Asn Gln
Tyr Gln Gln Asn
Tyr Arg Asp Val
Tyr Ser Pro Trp
Tyr Ser Trp Pro
Tyr Val Asp Arg
Tyr Val Arg Asp
Tyr Trp Ala Ile
Tyr Trp Ala Leu
Tyr Trp Ile Ala
Tyr Trp Leu Ala
Tyr Trp Pro Ser
Tyr Trp Ser Pro
(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
butan-1-ol,[2,6-di(propan-2-yl)phenyl]imino-(2-methyl-2-phenylpropylidene)molybdenum
1-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N-methyl-3,4-dihydro-2H-1,5-benzodioxepin-7-sulfonamide
1-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
1-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
N-[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenylphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]methanesulfonamide
N-[(2R,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenylphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]methanesulfonamide
1-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-1-methyl-3-[3-(2-pyridinyloxy)phenyl]urea
(1R)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-1-[2-(4-morpholinyl)-1-oxoethyl]-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,3-azetidine]carboxamide
N-[(2R,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2S,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2R,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2S,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2R,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2R,3R)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-(phenylmethyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-4-methylbenzenesulfonamide
N-[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenylphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]methanesulfonamide
N-[(2S,3S)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenylphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]methanesulfonamide
N-[(2R,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenylphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]methanesulfonamide
(3R)-2-tert-butylsulfinyl-3-(2-hydroxyethyl)-N-(2-methoxyethyl)-4-[3-(3-methoxyphenyl)phenyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide
(1S)-N-(4-fluorophenyl)-1-(hydroxymethyl)-7-methoxy-9-methyl-1-[2-(4-morpholinyl)-1-oxoethyl]-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,3-azetidine]carboxamide
2-amino-3-[[3-butanoyloxy-2-[(Z)-pentadec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
2-amino-3-[[3-hexanoyloxy-2-[(Z)-tridec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
2-amino-3-[[2-[(Z)-hexadec-9-enoyl]oxy-3-propanoyloxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
2-amino-3-[hydroxy-[3-pentanoyloxy-2-[(Z)-tetradec-9-enoyl]oxypropoxy]phosphoryl]oxypropanoic acid
3-[[3-acetyloxy-2-[(Z)-heptadec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxy-2-aminopropanoic acid
AKT inhibitor VIII
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.