Exact Mass: 504.2405642

Exact Mass Matches: 504.2405642

Found 1 metabolites which its exact mass value is equals to given mass value 504.2405642, within given mass tolerance error 6.4E-8 dalton. Try search metabolite list with more accurate mass tolerance error 1.28E-8 dalton.

SR 12813

4-[2,2-Bis(diethoxyphosphoryl)ethenyl]-2,6-ditert-butylphenol

C24H42O7P2 (504.2405642)


D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM[1][2]. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR)[3].