Exact Mass: 495.22332180000006

Exact Mass Matches: 495.22332180000006

Found 30 metabolites which its exact mass value is equals to given mass value 495.22332180000006, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

WYE-354

Methyl 4-[6-[4-(methoxycarbonylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate

C24H29N7O5 (495.22300640000003)


WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro[3]. WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro[3].

   

Gly His Pro Trp

(2S)-2-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(1H-indol-3-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Gly His Trp Pro

(2S)-1-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-3-(1H-indol-3-yl)propanoyl]pyrrolidine-2-carboxylic acid

C24H29N7O5 (495.22300640000003)


   

Gly Pro His Trp

(2S)-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanamido]-3-(1H-indol-3-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Gly Pro Trp His

(2S)-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-(1H-indol-3-yl)propanamido]-3-(1H-imidazol-4-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Gly Trp His Pro

(2S)-1-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-indol-3-yl)propanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxylic acid

C24H29N7O5 (495.22300640000003)


   

Gly Trp Pro His

(2S)-2-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-3-(1H-indol-3-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

His Gly Pro Trp

(2S)-2-{[(2S)-1-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetyl}pyrrolidin-2-yl]formamido}-3-(1H-indol-3-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

His Gly Trp Pro

(2S)-1-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-3-(1H-indol-3-yl)propanoyl]pyrrolidine-2-carboxylic acid

C24H29N7O5 (495.22300640000003)


   

His Pro Gly Trp

(2S)-2-(2-{[(2S)-1-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}acetamido)-3-(1H-indol-3-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

His Pro Trp Gly

2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(1H-indol-3-yl)propanamido]acetic acid

C24H29N7O5 (495.22300640000003)


   

His Trp Gly Pro

(2S)-1-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-(1H-indol-3-yl)propanamido]acetyl}pyrrolidine-2-carboxylic acid

C24H29N7O5 (495.22300640000003)


   

His Trp Pro Gly

2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-(1H-indol-3-yl)propanoyl]pyrrolidin-2-yl]formamido}acetic acid

C24H29N7O5 (495.22300640000003)


   

Pro Gly His Trp

(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}propanamido]-3-(1H-indol-3-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Pro Gly Trp His

(2S)-3-(1H-imidazol-4-yl)-2-[(2S)-3-(1H-indol-3-yl)-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}propanamido]propanoic acid

C24H29N7O5 (495.22300640000003)


   

Pro His Gly Trp

(2S)-2-{2-[(2S)-3-(1H-imidazol-4-yl)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]acetamido}-3-(1H-indol-3-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Pro His Trp Gly

2-[(2S)-2-[(2S)-3-(1H-imidazol-4-yl)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]-3-(1H-indol-3-yl)propanamido]acetic acid

C24H29N7O5 (495.22300640000003)


   

Pro Trp Gly His

(2S)-3-(1H-imidazol-4-yl)-2-{2-[(2S)-3-(1H-indol-3-yl)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]acetamido}propanoic acid

C24H29N7O5 (495.22300640000003)


   

Pro Trp His Gly

2-[(2S)-3-(1H-imidazol-4-yl)-2-[(2S)-3-(1H-indol-3-yl)-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]propanamido]acetic acid

C24H29N7O5 (495.22300640000003)


   

Trp Gly His Pro

(2S)-1-[(2S)-2-{2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]acetamido}-3-(1H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxylic acid

C24H29N7O5 (495.22300640000003)


   

Trp Gly Pro His

(2S)-2-{[(2S)-1-{2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]acetyl}pyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Trp His Gly Pro

(2S)-1-{2-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-3-(1H-imidazol-4-yl)propanamido]acetyl}pyrrolidine-2-carboxylic acid

C24H29N7O5 (495.22300640000003)


   

Trp His Pro Gly

2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-(1H-indol-3-yl)propanamido]-3-(1H-imidazol-4-yl)propanoyl]pyrrolidin-2-yl]formamido}acetic acid

C24H29N7O5 (495.22300640000003)


   

Trp Pro Gly His

(2S)-2-(2-{[(2S)-1-[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]pyrrolidin-2-yl]formamido}acetamido)-3-(1H-imidazol-4-yl)propanoic acid

C24H29N7O5 (495.22300640000003)


   

Trp Pro His Gly

2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-(1H-imidazol-4-yl)propanamido]acetic acid

C24H29N7O5 (495.22300640000003)


   
   
   

3-[[3-acetyloxy-2-[(Z)-tridec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxy-2-aminopropanoic acid

3-[[3-acetyloxy-2-[(Z)-tridec-9-enoyl]oxypropoxy]-hydroxyphosphoryl]oxy-2-aminopropanoic acid

C21H38NO10P (495.22332180000006)