Exact Mass: 494.1521

Exact Mass Matches: 494.1521

Found 1 metabolites which its exact mass value is equals to given mass value 494.1521, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

CCG273441

CCG273441

C26H24ClFN4O3 (494.1521)


CCG273441 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) with an IC50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC50=4.8 μM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle[1].