Exact Mass: 494.1521

Exact Mass Matches: 494.1521

Found 1 metabolites which its exact mass value is equals to given mass value 494.1521, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

CCG273441

CCG273441

C26H24ClFN4O3 (494.1521)


CCG273441 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) with an IC50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC50=4.8 μM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle[1].