Exact Mass: 493.2464
Exact Mass Matches: 493.2464
Found 324 metabolites which its exact mass value is equals to given mass value 493.2464
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Epo A
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.
Epothilone A
Ala Glu Phe Lys
Ala Glu Lys Phe
Ala Phe Glu Lys
Ala Phe Lys Glu
Ala Ile Gln Tyr
Ala Ile Tyr Gln
Ala Lys Glu Phe
Ala Lys Phe Glu
Ala Leu Gln Tyr
Ala Leu Tyr Gln
Ala Gln Ile Tyr
Ala Gln Leu Tyr
Ala Gln Tyr Ile
Ala Gln Tyr Leu
Ala Tyr Ile Gln
Ala Tyr Leu Gln
Ala Tyr Gln Ile
Ala Tyr Gln Leu
Cys Ile Lys Met
Cys Ile Met Lys
Cys Lys Ile Met
Cys Lys Leu Met
Cys Lys Met Ile
Cys Lys Met Leu
Cys Leu Lys Met
Cys Leu Met Lys
Cys Met Ile Lys
Cys Met Lys Ile
Cys Met Lys Leu
Cys Met Leu Lys
Glu Ala Phe Lys
Glu Ala Lys Phe
Glu Phe Ala Lys
Glu Phe Lys Ala
Glu Lys Ala Phe
Glu Lys Phe Ala
Phe Ala Glu Lys
Phe Ala Lys Glu
Phe Glu Ala Lys
Phe Glu Lys Ala
Phe Ile Asn Thr
Phe Ile Gln Ser
Phe Ile Ser Gln
Phe Ile Thr Asn
Phe Lys Ala Glu
Phe Lys Glu Ala
Phe Leu Asn Thr
Phe Leu Gln Ser
Phe Leu Ser Gln
Phe Leu Thr Asn
Phe Asn Ile Thr
Phe Asn Leu Thr
Phe Asn Thr Ile
Phe Asn Thr Leu
Phe Gln Ile Ser
Phe Gln Leu Ser
Phe Gln Ser Ile
Phe Gln Ser Leu
Phe Gln Thr Val
Phe Gln Val Thr
Phe Ser Ile Gln
Phe Ser Leu Gln
Phe Ser Gln Ile
Phe Ser Gln Leu
Phe Thr Ile Asn
Phe Thr Leu Asn
Phe Thr Asn Ile
Phe Thr Asn Leu
Phe Thr Gln Val
Phe Thr Val Gln
Phe Val Gln Thr
Phe Val Thr Gln
Ile Ala Gln Tyr
Ile Ala Tyr Gln
Ile Cys Lys Met
Ile Cys Met Lys
Ile Phe Asn Thr
Ile Phe Gln Ser
Ile Phe Ser Gln
Ile Phe Thr Asn
Ile Lys Cys Met
Ile Lys Met Cys
Ile Met Cys Lys
Ile Met Lys Cys
Ile Asn Phe Thr
Ile Asn Thr Phe
Ile Gln Ala Tyr
Ile Gln Phe Ser
Ile Gln Ser Phe
Ile Gln Tyr Ala
Ile Ser Phe Gln
Ile Ser Gln Phe
Ile Thr Phe Asn
Ile Thr Asn Phe
Ile Tyr Ala Gln
Ile Tyr Gln Ala
Lys Ala Glu Phe
Lys Ala Phe Glu
Lys Cys Ile Met
Lys Cys Leu Met
Lys Cys Met Ile
Lys Cys Met Leu
Lys Glu Ala Phe
Lys Glu Phe Ala
Lys Phe Ala Glu
Lys Phe Glu Ala
Lys Ile Cys Met
Lys Ile Met Cys
Lys Leu Cys Met
Lys Leu Met Cys
Lys Met Cys Ile
Lys Met Cys Leu
Lys Met Ile Cys
Lys Met Leu Cys
Lys Pro Ser Tyr
Lys Pro Tyr Ser
Lys Ser Pro Tyr
Lys Ser Tyr Pro
Lys Tyr Pro Ser
Lys Tyr Ser Pro
Leu Ala Gln Tyr
Leu Ala Tyr Gln
Leu Cys Lys Met
Leu Cys Met Lys
Leu Phe Asn Thr
Leu Phe Gln Ser
Leu Phe Ser Gln
Leu Phe Thr Asn
Leu Lys Cys Met
Leu Lys Met Cys
Leu Met Cys Lys
Leu Met Lys Cys
Leu Asn Phe Thr
Leu Asn Thr Phe
Leu Gln Ala Tyr
Leu Gln Phe Ser
Leu Gln Ser Phe
Leu Gln Tyr Ala
Leu Ser Phe Gln
Leu Ser Gln Phe
Leu Thr Phe Asn
Leu Thr Asn Phe
Leu Tyr Ala Gln
Leu Tyr Gln Ala
Met Cys Ile Lys
Met Cys Lys Ile
Met Cys Lys Leu
Met Cys Leu Lys
Met Ile Cys Lys
Met Ile Lys Cys
Met Lys Cys Ile
Met Lys Cys Leu
Met Lys Ile Cys
Met Lys Leu Cys
Met Leu Cys Lys
Met Leu Lys Cys
Asn Phe Ile Thr
Asn Phe Leu Thr
Asn Phe Thr Ile
Asn Phe Thr Leu
Asn Ile Phe Thr
Asn Ile Thr Phe
Asn Leu Phe Thr
Asn Leu Thr Phe
Asn Thr Phe Ile
Asn Thr Phe Leu
Asn Thr Ile Phe
Asn Thr Leu Phe
Asn Val Val Tyr
Asn Val Tyr Val
Asn Tyr Val Val
Pro Lys Ser Tyr
Pro Lys Tyr Ser
Pro Ser Lys Tyr
Pro Ser Tyr Lys
Pro Tyr Lys Ser
Pro Tyr Ser Lys
Gln Ala Ile Tyr
Gln Ala Leu Tyr
Gln Ala Tyr Ile
Gln Ala Tyr Leu
Gln Phe Ile Ser
Gln Phe Leu Ser
Gln Phe Ser Ile
Gln Phe Ser Leu
Gln Phe Thr Val
Gln Phe Val Thr
Gln Ile Ala Tyr
Gln Ile Phe Ser
Gln Ile Ser Phe
Gln Ile Tyr Ala
Gln Leu Ala Tyr
Gln Leu Phe Ser
Gln Leu Ser Phe
Gln Leu Tyr Ala
Gln Ser Phe Ile
Gln Ser Phe Leu
Gln Ser Ile Phe
Gln Ser Leu Phe
Gln Thr Phe Val
Gln Thr Val Phe
Gln Val Phe Thr
Gln Val Thr Phe
Gln Tyr Ala Ile
Gln Tyr Ala Leu
Gln Tyr Ile Ala
Gln Tyr Leu Ala
Ser Phe Ile Gln
Ser Phe Leu Gln
Ser Phe Gln Ile
Ser Phe Gln Leu
Ser Ile Phe Gln
Ser Ile Gln Phe
Ser Lys Pro Tyr
Ser Lys Tyr Pro
Ser Leu Phe Gln
Ser Leu Gln Phe
Ser Pro Lys Tyr
Ser Pro Tyr Lys
Ser Gln Phe Ile
Ser Gln Phe Leu
Ser Gln Ile Phe
Ser Gln Leu Phe
Ser Tyr Lys Pro
Ser Tyr Pro Lys
Thr Phe Ile Asn
Thr Phe Leu Asn
Thr Phe Asn Ile
Thr Phe Asn Leu
Thr Phe Gln Val
Thr Phe Val Gln
Thr Ile Phe Asn
Thr Ile Asn Phe
Thr Leu Phe Asn
Thr Leu Asn Phe
Thr Asn Phe Ile
Thr Asn Phe Leu
Thr Asn Ile Phe
Thr Asn Leu Phe
Thr Gln Phe Val
Thr Gln Val Phe
Thr Val Phe Gln
Thr Val Gln Phe
Val Phe Gln Thr
Val Phe Thr Gln
Val Asn Val Tyr
Val Asn Tyr Val
Val Gln Phe Thr
Val Gln Thr Phe
Val Thr Phe Gln
Val Thr Gln Phe
Val Val Asn Tyr
Val Val Tyr Asn
Val Tyr Asn Val
Val Tyr Val Asn
Tyr Ala Ile Gln
Tyr Ala Leu Gln
Tyr Ala Gln Ile
Tyr Ala Gln Leu
Tyr Ile Ala Gln
Tyr Ile Gln Ala
Tyr Lys Pro Ser
Tyr Lys Ser Pro
Tyr Leu Ala Gln
Tyr Leu Gln Ala
Tyr Asn Val Val
Tyr Pro Lys Ser
Tyr Pro Ser Lys
Tyr Gln Ala Ile
Tyr Gln Ala Leu
Tyr Gln Ile Ala
Tyr Gln Leu Ala
Tyr Ser Lys Pro
Tyr Ser Pro Lys
Tyr Val Asn Val
Tyr Val Val Asn
N-[3-[(4-ethoxyphenyl)-[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-4,5-dimethyl-2-thiophenyl]benzamide
6-chloro-2-[4-(4,4-difluoropiperidin-1-yl)butylamino]-N-(2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide
7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide
[(1S)-2-[(4-chlorophenyl)methyl]-1-(cyclopropylmethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol
[(1R)-2-[(4-chlorophenyl)methyl]-1-(cyclopropylmethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol
(2S,3S)-10-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2S,3S)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(1S,9R,10R,11R)-12-(cyclobutanecarbonyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-11-(piperidine-1-carbonyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-dien-6-one
(1S,9R,10R,11R)-N-cyclopentyl-12-(2-cyclopropylacetyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(2R,3R)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3R)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(1R,9S,10S,11S)-12-(cyclobutanecarbonyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-11-(piperidine-1-carbonyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-dien-6-one
(2R,3R,3aS,9bS)-7-(1-cyclohexenyl)-N-[(4-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-1-(1-oxopropyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
(2S,3S)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3R)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2S,3R)-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(2R,3S)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-6-one
(1R,9S,10S,11S)-N-cyclopentyl-12-(2-cyclopropylacetyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide
(2S,3S,3aR,9bR)-7-(1-cyclohexenyl)-N-[(4-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-1-(1-oxopropyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide
2-amino-3-[[3-[(9Z,12Z)-hexadeca-9,12-dienoyl]oxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxypropanoic acid
Epothilone A
An epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer). C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.