Exact Mass: 493.242403

Epo A

C26H39NO6S (493.24979540000004)

C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.

Epothilone A

C26H39NO6S (493.24979540000004)

Epothilone C7

C26H39NO6S (493.24979540000004)

Epothilone C9

C26H39NO6S (493.24979540000004)

15-Veratroylpseudokobusine

C29H35NO6 (493.24642500000004)

Bacilosarcin B

C24H35N3O8 (493.242403)

MMV667494

C25H34ClF2N5O (493.2419808)

C4-desmethyl-epothilone B

C26H39NO6S (493.24979540000004)

MMV667494

C25H34N5OClF2 (493.2419808000001)

Ala Ala Phe Trp

C26H31N5O5 (493.2325076)

Ala Ala Trp Phe

C26H31N5O5 (493.2325076)

Ala Phe Ala Trp

C26H31N5O5 (493.2325076)

Ala Phe Trp Ala

C26H31N5O5 (493.2325076)

Ala Trp Ala Phe

C26H31N5O5 (493.2325076)

Ala Trp Phe Ala

C26H31N5O5 (493.2325076)

Cys Phe Lys Pro

C23H35N5O5S (493.23587800000007)

Cys Phe Pro Lys

C23H35N5O5S (493.23587800000007)

Cys Ile Lys Met

C20H39N5O5S2 (493.2392484)

Cys Ile Met Lys

C20H39N5O5S2 (493.2392484)

Cys Lys Phe Pro

C23H35N5O5S (493.23587800000007)

Cys Lys Ile Met

C20H39N5O5S2 (493.2392484)

Cys Lys Leu Met

C20H39N5O5S2 (493.2392484)

Cys Lys Met Ile

C20H39N5O5S2 (493.2392484)

Cys Lys Met Leu

C20H39N5O5S2 (493.2392484)

Cys Lys Pro Phe

C23H35N5O5S (493.23587800000007)

Cys Leu Lys Met

C20H39N5O5S2 (493.2392484)

Cys Leu Met Lys

C20H39N5O5S2 (493.2392484)

Cys Met Ile Lys

C20H39N5O5S2 (493.2392484)

Cys Met Lys Ile

C20H39N5O5S2 (493.2392484)

Cys Met Lys Leu

C20H39N5O5S2 (493.2392484)

Cys Met Leu Lys

C20H39N5O5S2 (493.2392484)

Cys Pro Phe Lys

C23H35N5O5S (493.23587800000007)

Cys Pro Lys Phe

C23H35N5O5S (493.23587800000007)

Phe Ala Ala Trp

C26H31N5O5 (493.2325076)

Phe Ala Trp Ala

C26H31N5O5 (493.2325076)

Phe Cys Lys Pro

C23H35N5O5S (493.23587800000007)

Phe Cys Pro Lys

C23H35N5O5S (493.23587800000007)

Phe Lys Cys Pro

C23H35N5O5S (493.23587800000007)

Phe Lys Pro Cys

C23H35N5O5S (493.23587800000007)

Phe Pro Cys Lys

C23H35N5O5S (493.23587800000007)

Phe Pro Lys Cys

C23H35N5O5S (493.23587800000007)

Phe Trp Ala Ala

C26H31N5O5 (493.2325076)

Ile Cys Lys Met

C20H39N5O5S2 (493.2392484)

Ile Cys Met Lys

C20H39N5O5S2 (493.2392484)

Ile Lys Cys Met

C20H39N5O5S2 (493.2392484)

Ile Lys Met Cys

C20H39N5O5S2 (493.2392484)

Ile Met Cys Lys

C20H39N5O5S2 (493.2392484)

Ile Met Lys Cys

C20H39N5O5S2 (493.2392484)

Lys Cys Phe Pro

C23H35N5O5S (493.23587800000007)

Lys Cys Ile Met

C20H39N5O5S2 (493.2392484)

Lys Cys Leu Met

C20H39N5O5S2 (493.2392484)

Lys Cys Met Ile

C20H39N5O5S2 (493.2392484)

Lys Cys Met Leu

C20H39N5O5S2 (493.2392484)

Lys Cys Pro Phe

C23H35N5O5S (493.23587800000007)

Lys Phe Cys Pro

C23H35N5O5S (493.23587800000007)

Lys Phe Pro Cys

C23H35N5O5S (493.23587800000007)

Lys Ile Cys Met

C20H39N5O5S2 (493.2392484)

Lys Ile Met Cys

C20H39N5O5S2 (493.2392484)

Lys Leu Cys Met

C20H39N5O5S2 (493.2392484)

Lys Leu Met Cys

C20H39N5O5S2 (493.2392484)

Lys Met Cys Ile

C20H39N5O5S2 (493.2392484)

Lys Met Cys Leu

C20H39N5O5S2 (493.2392484)

Lys Met Ile Cys

C20H39N5O5S2 (493.2392484)

Lys Met Leu Cys

C20H39N5O5S2 (493.2392484)

Lys Pro Cys Phe

C23H35N5O5S (493.23587800000007)

Lys Pro Phe Cys

C23H35N5O5S (493.23587800000007)

Leu Cys Lys Met

C20H39N5O5S2 (493.2392484)

Leu Cys Met Lys

C20H39N5O5S2 (493.2392484)

Leu Lys Cys Met

C20H39N5O5S2 (493.2392484)

Leu Lys Met Cys

C20H39N5O5S2 (493.2392484)

Leu Met Cys Lys

C20H39N5O5S2 (493.2392484)

Leu Met Lys Cys

C20H39N5O5S2 (493.2392484)

Met Cys Ile Lys

C20H39N5O5S2 (493.2392484)

Met Cys Lys Ile

C20H39N5O5S2 (493.2392484)

Met Cys Lys Leu

C20H39N5O5S2 (493.2392484)

Met Cys Leu Lys

C20H39N5O5S2 (493.2392484)

Met Ile Cys Lys

C20H39N5O5S2 (493.2392484)

Met Ile Lys Cys

C20H39N5O5S2 (493.2392484)

Met Lys Cys Ile

C20H39N5O5S2 (493.2392484)

Met Lys Cys Leu

C20H39N5O5S2 (493.2392484)

Met Lys Ile Cys

C20H39N5O5S2 (493.2392484)

Met Lys Leu Cys

C20H39N5O5S2 (493.2392484)

Met Leu Cys Lys

C20H39N5O5S2 (493.2392484)

Met Leu Lys Cys

C20H39N5O5S2 (493.2392484)

Pro Cys Phe Lys

C23H35N5O5S (493.23587800000007)

Pro Cys Lys Phe

C23H35N5O5S (493.23587800000007)

Pro Phe Cys Lys

C23H35N5O5S (493.23587800000007)

Pro Phe Lys Cys

C23H35N5O5S (493.23587800000007)

Pro Lys Cys Phe

C23H35N5O5S (493.23587800000007)

Pro Lys Phe Cys

C23H35N5O5S (493.23587800000007)

Trp Ala Ala Phe

C26H31N5O5 (493.2325076)

Trp Ala Phe Ala

C26H31N5O5 (493.2325076)

Trp Phe Ala Ala

C26H31N5O5 (493.2325076)

p,p-DDA

C28H35N3O3S (493.23990000000003)

Etanautine

C26H31N5O5 (493.2325076)

N - Nervous system > N04 - Anti-parkinson drugs > N04A - Anticholinergic agents > N04AB - Ethers chemically close to antihistamines

N-[3-[(4-ethoxyphenyl)-[4-(2-hydroxyethyl)-1-piperazinyl]methyl]-4,5-dimethyl-2-thiophenyl]benzamide

C28H35N3O3S (493.23990000000003)

6-chloro-2-[4-(4,4-difluoropiperidin-1-yl)butylamino]-N-(2-pyrrolidin-1-ylethyl)quinoline-4-carboxamide

C25H34ClF2N5O (493.2419808)

7,11-dihydroxy-8,8,10,12-tetramethyl-3-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione

C26H39NO6S (493.24979540000004)

Neoansamycin C

C29H35NO6 (493.24642500000004)

4-[[(4-ethylphenyl)sulfonylamino]methyl]-N-[2-[(phenylmethyl)-propan-2-ylamino]ethyl]benzamide

C28H35N3O3S (493.23990000000003)

N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

[(1S)-2-[(4-chlorophenyl)methyl]-1-(cyclopropylmethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol

C29H36ClN3O2 (493.24959060000003)

[(1R)-2-[(4-chlorophenyl)methyl]-1-(cyclopropylmethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]methanol

C29H36ClN3O2 (493.24959060000003)

Vorapaxar(1+)

C29H34FN2O4+ (493.2502476)

N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

(3R,6aR,8S,10aR)-N-(4-chlorophenyl)-8-[2-(cyclohexylmethylamino)-2-oxoethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocine-1-carboxamide

C25H36ClN3O5 (493.23433560000007)

N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

(3S,6aR,8R,10aR)-N-(4-chlorophenyl)-8-[2-(cyclohexylmethylamino)-2-oxoethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocine-1-carboxamide

C25H36ClN3O5 (493.23433560000007)

(3S,6aR,8S,10aR)-N-(4-chlorophenyl)-8-[2-(cyclohexylmethylamino)-2-oxoethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocine-1-carboxamide

C25H36ClN3O5 (493.23433560000007)

(1S,9R,10R,11R)-12-(cyclobutanecarbonyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-11-(piperidine-1-carbonyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-dien-6-one

C28H32FN3O4 (493.2376724)

(1S,9R,10R,11R)-N-cyclopentyl-12-(2-cyclopropylacetyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C28H32FN3O4 (493.2376724)

N-[[(2R,3S)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(2S,3R)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(2S,3S)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(2R,3R)-9-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,14,15-tetrazabicyclo[10.3.0]pentadeca-12,14-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

(3R,6aS,8R,10aS)-N-(4-chlorophenyl)-8-[2-(cyclohexylmethylamino)-2-oxoethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocine-1-carboxamide

C25H36ClN3O5 (493.23433560000007)

(1R,9S,10S,11S)-12-(cyclobutanecarbonyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-11-(piperidine-1-carbonyl)-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-dien-6-one

C28H32FN3O4 (493.2376724)

(2R,3R,3aS,9bS)-7-(1-cyclohexenyl)-N-[(4-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-1-(1-oxopropyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

C28H32FN3O4 (493.2376724)

N-[[(2S,3S)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(2R,3R)-9-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-2-yl]methyl]-N,1-dimethyl-4-imidazolesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,4-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2R)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,3-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8S,9R)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

N-[[(8R,9S)-6-[(2S)-1-hydroxypropan-2-yl]-8-methyl-5-oxo-10-oxa-1,6,13,14-tetrazabicyclo[10.2.1]pentadeca-12(15),13-dien-9-yl]methyl]-N,2-dimethylbenzenesulfonamide

C23H35N5O5S (493.23587800000007)

(3R,6aS,8S,10aS)-N-(4-chlorophenyl)-8-[2-(cyclohexylmethylamino)-2-oxoethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocine-1-carboxamide

C25H36ClN3O5 (493.23433560000007)

(3S,6aS,8R,10aS)-N-(4-chlorophenyl)-8-[2-(cyclohexylmethylamino)-2-oxoethyl]-3-hydroxy-3,4,6,6a,8,9,10,10a-octahydro-2H-pyrano[2,3-c][1,5]oxazocine-1-carboxamide

C25H36ClN3O5 (493.23433560000007)

(1R,9S,10S,11S)-N-cyclopentyl-12-(2-cyclopropylacetyl)-5-(2-fluorophenyl)-10-(hydroxymethyl)-6-oxo-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C28H32FN3O4 (493.2376724)

(2S,3S,3aR,9bR)-7-(1-cyclohexenyl)-N-[(4-fluorophenyl)methyl]-3-(hydroxymethyl)-6-oxo-1-(1-oxopropyl)-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

C28H32FN3O4 (493.2376724)

N-benzoylglycyl-N(6)-[2-hydroxy-3-(quinoxalin-2-yl)propyl]lysine

C26H31N5O5 (493.2325076)

N-benzoylglycyl-N(6)-[2-hydroxy-2-(3-methylquinoxalin-2-yl)ethyl]lysine

C26H31N5O5 (493.2325076)

2-amino-3-[[3-[(9Z,12Z)-hexadeca-9,12-dienoyl]oxy-2-hydroxypropoxy]-hydroxyphosphoryl]oxypropanoic acid

C22H40NO9P (493.24405600000006)

Epothilone A

C26H39NO6S (493.24979540000004)

An epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the 13R,14S diastereoisomer). C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C273 - Antimitotic Agent D050258 - Mitosis Modulators > D050256 - Antimitotic Agents > D050257 - Tubulin Modulators D000970 - Antineoplastic Agents > D050256 - Antimitotic Agents Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.

(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-5,7,9,9-tetramethyl-14-[1-(2-methyl-4-thiazolyl)prop-1-en-2-yl]-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione

C26H39NO6S (493.24979540000004)

LPS 16:2

C22H40NO9P (493.24405600000006)

ST 20:0;O6;Tau

C22H39NO9S (493.2345404)

ST 24:4;O3;Tau

C26H39NO6S (493.24979540000004)

(4s,7r,8s,9s,13z,15s,16r)-4,8,15-trihydroxy-5,5,7,9-tetramethyl-16-[(1e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

C26H39NO6S (493.24979540000004)

(4s,7r,8s,9s,13z,16s)-4,8-dihydroxy-16-[(1e)-3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-5,5,7,9-tetramethyl-1-oxacyclohexadec-13-ene-2,6-dione

C26H39NO6S (493.24979540000004)

4,8-dihydroxy-16-[3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-5,5,7,9-tetramethyl-1-oxacyclohexadec-13-ene-2,6-dione

C26H39NO6S (493.24979540000004)

(4s,7r,8s,13z,15s,16r)-4,8,15-trihydroxy-5,5,7,9-tetramethyl-16-[(1e)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

C26H39NO6S (493.24979540000004)

(1r,5s,8r,9s,11r,13r,14r,16r,17r,18s,19r)-16,19-dihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-13-yl 3,4-dimethoxybenzoate

C29H35NO6 (493.24642500000004)

(1r,8r,9s,11r,13r,14r,16r,17r,18s,19r)-16,19-dihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁷,¹⁶.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-13-yl 3,4-dimethoxybenzoate

C29H35NO6 (493.24642500000004)

(1s,3z,8s,10s,11r,12s,15s)-12-butyl-4-ethyl-13,20-dihydroxy-8-methoxy-10-methyl-2-oxa-14-azahexacyclo[13.7.1.0¹,¹⁰.0³,²¹.0¹¹,¹⁵.0¹⁷,²²]tricosa-3,13,17(22),18,20-pentaene-9,16-dione

C29H35NO6 (493.24642500000004)

(2s)-2-hydroxy-n-[(1s)-1-[(3s)-8-hydroxy-1-oxo-3,4-dihydro-2-benzopyran-3-yl]-3-methylbutyl]-2-[(2s,3s,5s,6s)-6-hydroxy-3-(c-hydroxycarbonimidoylmethyl)-5,6-dimethylmorpholin-2-yl]ethanimidic acid

C24H35N3O8 (493.242403)

(4s,7r,8s,13z,16s)-4,8-dihydroxy-16-[(1e)-3-hydroxy-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-5,5,7,9-tetramethyl-1-oxacyclohexadec-13-ene-2,6-dione

C26H39NO6S (493.24979540000004)

2-hydroxy-n-[1-(8-hydroxy-1-oxo-3,4-dihydro-2-benzopyran-3-yl)-3-methylbutyl]-2-[6-hydroxy-3-(c-hydroxycarbonimidoylmethyl)-5,6-dimethylmorpholin-2-yl]ethanimidic acid

C24H35N3O8 (493.242403)

4,8,15-trihydroxy-5,5,7,9-tetramethyl-16-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

C26H39NO6S (493.24979540000004)