Exact Mass: 484.18119740000003
Exact Mass Matches: 484.18119740000003
Found 281 metabolites which its exact mass value is equals to given mass value 484.18119740000003
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Nb-trans-p-Coumaroylserotonin glucoside
Nb-trans-p-Coumaroylserotonin glucoside is found in fats and oils. It is an alkaloid from Carthamus tinctorius (safflower) If neurons that make serotonin serotonergic neurons are abnormal in infants, there is a risk of sudden infant death syndrome (SIDS). Low levels of serotonin may also be associated with intense spiritual experiences. In animals including humans, serotonin is synthesized from the amino acid L-tryptophan by a short metabolic pathway consisting of two enzymes: tryptophan hydroxylase (TPH) and amino acid decarboxylase (DDC). The TPH-mediated reaction is the rate-limiting step in the pathway. TPH has been shown to exist in two forms: TPH1, found in several tissues, and TPH2, which is a brain-specific isoform. There is evidence that genetic polymorphisms in both these subtypes influence susceptibility to anxiety and depression in humans.[citation needed] The 5-HTT gene regulates a chemical called serotonin. This chemical is found in very low amounts in people diagnosed with depression compared to other people. Serotonin works as a neurotransmitter and helps with the modulation of things such as anger, appetite, sexuality, sleep, mood, and several other things. People with depression often have impaired 5-HTT genes. There are two forms of the 5-HTT gene and everyone has two 5-HTT genes. (Levinson) There is a long form of 5-HTT and a short form of 5-HTT. Research shows that people with both 5-HTT genes being the long form are less likely to become depressed while people with one short and one long or two short forms are more likely to develop depression. Research is still being conducted to find more information. There is also evidence that ovarian hormones can affect the expression of TPH in various species, suggesting a possible mechanism for postpartum depression and premenstrual stress syndrome.[citation needed] Serotonin biosynthesis in plants likewise begins with L-tryptophan, which is however first decarboxylated by tryptophan decarboxylase to give tryptamine, which is then hydroxylated by the cytochrome P450 monooxygenase, tryptamine 5-hydroxylase, yielding serotonin. Serotonin is a biochemical messenger and regulator, synthesized from the essential amino acid L-Tryptophan. Serotonin in the nervous system acts as a local transmitter at synapses, and as a paracrine or hormonal modulator of circuits upon diffusion, allowing a wide variety of "state-dependent" behavioral responses to different stimuli. Serotonin is widely distributed in the nervous system of vertebrates and invertebrates and some of its behavioral effects have been preserved along evolution. Such is the case of aggressive behavior and rhythmic motor patterns , including those responsible for feeding. In vertebrates, which display a wider and much more sophisticated behavioral repertoire, serotonin also modulates sleep , the arousal state , sexual behavior, and others, and deficiencies of the serotonergic system causes disorders such as depression, obsessive-compulsive disorder, phobias, posttraumatic stress disorder, epilepsy, and generalized anxiety disorder. Serotonin has three different modes of action in the nervous system: as transmitter, acting locally at synaptic boutons; Serotonin is a monoamine neurotransmitter. It is found extensively in the gastrointestinal tract of animals, and about 80 to 90 percent of the human bodys total serotonin is located in the enterochromaffin cells in the gut, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic neurons in the central nervous system (CNS) where it has various functions, including the regulation of mood, appetite, sleep, muscle contraction, and some cognitive functions including memory and learning. Serotonin levels can not be increased by diet alone. For example, increasing foods rich in tryptophan (e.g., meats, proteins) does not increase serotonin levels, due to competition with other amino acids. What is required to increase serotonin producti... Alkaloid from Carthamus tinctorius (safflower) [DFC]. Nb-trans-p-Coumaroylserotonin glucoside is found in fats and oils and herbs and spices.
Thamnosin
Thamnosin is found in citrus. Thamnosin is a constituent of Citrus grandis (pummelo)
Halobetasol Propionate
Halobetasol propionate is thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. It is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dukunolide E
Dukunolide F is found in fruits. Dukunolide F is a constituent of Lansium domesticum (langsat) Constituent of Lansium domesticum (langsat). Dukunolide E is found in fruits.
managlinat dialanetil
C21H33N4O5PS (484.1909178000001)
Evodol
Evodol is a natural product found in Dictamnus albus, Tetradium glabrifolium, and other organisms with data available.
diuvaretin
A member of the class of dihydrochalcones that is dihydrochalcone substituted by 2-hydroxybenzyl groups at positions 3 and 5, hydroxy groups at positions 2 and 4 and a methoxy group at position 6. Isolated from the roots of Uvaria acuminata and Uvaria chamae, it exhibits cytotoxicity towards human promyelocytic leukemia HL-60 cells.
(3R*,5S*,6S*,9S*,10S*)-3-bromo-6,12-diacetoxy-13-hydroxylabd-8(19),14-diene
(1S*,2S*,3S*,7R*,8S*,9R*,11R*,12S*,14R*)-7-bromotetradecahydro-12-hydroxy-1-isopropyl-8,12-dimethyl-4-methylenephenanthren-9,14-yl diacetate
(12R)-6alpha,19-diacetoxy-18-chloro-1beta,12-epoxy-4alpha-hydroxy-neo-clerod-13-en-15,16-olide|ajugaciliatin F
C24H33ClO8 (484.18638480000004)
(+-)-3r-(7-Methoxy-2-oxo-2H-chromen-8-yl)-4c-[trans-2-(7-methoxy-2-oxo-2H-chromen-8-yl)-vinyl]-1,4t-dimethyl-cyclohexen|(+-)-3r-(7-methoxy-2-oxo-2H-chromen-8-yl)-4c-[trans-2-(7-methoxy-2-oxo-2H-chromen-8-yl)-vinyl]-1,4t-dimethyl-cyclohexene
(+)-tephrorin B|(3S,4S)-4-[(2S)-3,4-dihydro-7-hydroxy-4-oxo-2-phenyl-2H-1-benzopyran-8-yl]tetrahydro-2,2-dimethyl-3-furanyl (2E)-3-phenyl-2-propenoate
7-[4-hydroxy-2-[2-(3-hydroxyphenyl)ethyl]-6-methoxyphenoxy]-2-methoxy-9,10-dihydrophenanthren-4-ol
C26H28O9_1H,3H-Oxireno[c]pyrano[4,3:2,3]furo[3,4:5,6]naphtho[1,2-d]pyran-3,8,10(6H,9aH)-trione, 12-(3-furanyl)-4,4a,8a,12,12a,13,14,14a-octahydro-7-hydroxy-6,6,8a,12a-tetramethyl-, (4aS,8aR,8bR,9aS,12S,12aS,14bR)
(2R,7S,13R,14R,16S,19R,20S)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione
(2R,7S,13R,14R,16S,19R,20S)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione_major
(2R,7S,13R,14R,16S,19R,20S)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,?.0²,¹?.0¹?,¹?.0¹?,²?]docos-10-ene-5,12,17-trione
Cys Cys Phe Ile
Cys Cys Phe Leu
Cys Cys Ile Phe
Cys Cys Leu Phe
Cys Glu His Pro
Cys Glu Pro His
Cys Phe Cys Ile
Cys Phe Cys Leu
Cys Phe Ile Cys
Cys Phe Leu Cys
Cys His Glu Pro
Cys His Pro Glu
Cys Ile Cys Phe
Cys Ile Phe Cys
Cys Leu Cys Phe
Cys Leu Phe Cys
Cys Pro Glu His
Cys Pro His Glu
Asp Ser Thr Tyr
C20H28N4O10 (484.18053480000003)
Asp Ser Tyr Thr
C20H28N4O10 (484.18053480000003)
Asp Thr Ser Tyr
C20H28N4O10 (484.18053480000003)
Asp Thr Tyr Ser
C20H28N4O10 (484.18053480000003)
Asp Tyr Ser Thr
C20H28N4O10 (484.18053480000003)
Asp Tyr Thr Ser
C20H28N4O10 (484.18053480000003)
Glu Cys His Pro
Glu Cys Pro His
Glu His Cys Pro
Glu His Pro Cys
Glu Pro Cys His
Glu Pro His Cys
Glu Ser Ser Tyr
C20H28N4O10 (484.18053480000003)
Glu Ser Tyr Ser
C20H28N4O10 (484.18053480000003)
Glu Tyr Ser Ser
C20H28N4O10 (484.18053480000003)
Phe Cys Cys Ile
Phe Cys Cys Leu
Phe Cys Ile Cys
Phe Cys Leu Cys
Phe Gly Met Met
Phe Ile Cys Cys
Phe Leu Cys Cys
Phe Met Gly Met
Phe Met Met Gly
Gly Phe Met Met
Gly Met Phe Met
Gly Met Met Phe
His Cys Glu Pro
His Cys Pro Glu
His Glu Cys Pro
His Glu Pro Cys
His Pro Cys Glu
His Pro Glu Cys
Ile Cys Cys Phe
Ile Cys Phe Cys
Ile Phe Cys Cys
Leu Cys Cys Phe
Leu Cys Phe Cys
Leu Phe Cys Cys
Met Phe Gly Met
Met Phe Met Gly
Met Gly Phe Met
Met Gly Met Phe
Met Met Phe Gly
Met Met Gly Phe
Pro Cys Glu His
Pro Cys His Glu
Pro Glu Cys His
Pro Glu His Cys
Pro His Cys Glu
Pro His Glu Cys
Ser Asp Thr Tyr
C20H28N4O10 (484.18053480000003)
Ser Asp Tyr Thr
C20H28N4O10 (484.18053480000003)
Ser Glu Ser Tyr
C20H28N4O10 (484.18053480000003)
Ser Glu Tyr Ser
C20H28N4O10 (484.18053480000003)
Ser Ser Glu Tyr
C20H28N4O10 (484.18053480000003)
Ser Ser Tyr Glu
C20H28N4O10 (484.18053480000003)
Ser Thr Asp Tyr
C20H28N4O10 (484.18053480000003)
Ser Thr Tyr Asp
C20H28N4O10 (484.18053480000003)
Ser Tyr Asp Thr
C20H28N4O10 (484.18053480000003)
Ser Tyr Glu Ser
C20H28N4O10 (484.18053480000003)
Ser Tyr Ser Glu
C20H28N4O10 (484.18053480000003)
Ser Tyr Thr Asp
C20H28N4O10 (484.18053480000003)
Thr Asp Ser Tyr
C20H28N4O10 (484.18053480000003)
Thr Asp Tyr Ser
C20H28N4O10 (484.18053480000003)
Thr Ser Asp Tyr
C20H28N4O10 (484.18053480000003)
Thr Ser Tyr Asp
C20H28N4O10 (484.18053480000003)
Thr Tyr Asp Ser
C20H28N4O10 (484.18053480000003)
Thr Tyr Ser Asp
C20H28N4O10 (484.18053480000003)
Tyr Asp Ser Thr
C20H28N4O10 (484.18053480000003)
Tyr Asp Thr Ser
C20H28N4O10 (484.18053480000003)
Tyr Glu Ser Ser
C20H28N4O10 (484.18053480000003)
Tyr Ser Asp Thr
C20H28N4O10 (484.18053480000003)
Tyr Ser Glu Ser
C20H28N4O10 (484.18053480000003)
Tyr Ser Ser Glu
C20H28N4O10 (484.18053480000003)
Tyr Ser Thr Asp
C20H28N4O10 (484.18053480000003)
Tyr Thr Asp Ser
C20H28N4O10 (484.18053480000003)
Tyr Thr Ser Asp
C20H28N4O10 (484.18053480000003)
(+)-Tephrorin B
A monohydroxyflavanone that is (2S)-7-hydroxyflavanone substituted at position 8 by a tetrahydrofuran ring which in turn is substituted by geminal methyl groups at position 2 and a cinnamoyloxy group at position 3. Isolated from Tephrosia purpurea, it exhibits antineoplastic activity.
halobetasol propionate
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
Thamnosin
5-Hydroxytryptamine
Dukunolide E
1-[[2-(2,5-Dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1-biphenyl]-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylic acid ethyl ester
Managlinat dialanetil
C21H33N4O5PS (484.1909178000001)
4-[[5-(aminocarbonyl)-2-methoxyphenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxy-2-Naphthalenecarboxamide
(3S,6S,7R,8R)-8-benzyl-3-{[(3-hydroxypyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate
N-cyclopropyl-4-[4-(3,4-dichlorophenyl)-2-(1-methylpiperidin-4-yl)-1-propyl-1H-imidazol-5-yl]pyrimidin-2-amine
4-(2-{[4-{[3-(4-Chlorophenyl)propyl]sulfanyl}-6-(1-piperazinyl)-1,3,5-triazin-2-YL]amino}ethyl)phenol
C24H29ClN6OS (484.18119740000003)
10-Hydroxy-5-methoxy-6-chloroarmillane
C24H33ClO8 (484.18638480000004)
Ajugaciliatin F
C24H33ClO8 (484.18638480000004)
A diterpene lactone isolated from the whole plants of Ajuga ciliata.
Thymidine dimer
C20H28N4O10 (484.18053480000003)
A nucleoside analogue obtained by formal cyclodimerisation of thymidine.
N-[2,5-diethoxy-4-[[oxo-(3,4,5-trimethoxyphenyl)methyl]amino]phenyl]-2-furancarboxamide
4-[[(1,5-Dimethyl-3-oxo-2-phenyl-4-pyrazolyl)amino]methylidene]-2-(2-furanylmethyl)-7-methoxyisoquinoline-1,3-dione
N-[5-(diethylsulfamoyl)-2-(4-morpholinyl)phenyl]-2-oxo-1H-quinoline-4-carboxamide
C24H28N4O5S (484.17803180000004)
3-[[1,3-benzodioxol-5-ylmethyl-[[1-(2-furanylmethyl)-5-tetrazolyl]methyl]amino]methyl]-6-methyl-1H-quinolin-2-one
(2S,3R)-3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-10-(3-methylbut-2-en-1-yl)-1-oxo-1,2,3,4-tetrahydroanthracen-2-yl acetate
2-[3-[(2,6-Dimethylphenoxy)methyl]-4-methoxyphenyl]-3-(thiophen-2-ylmethyl)-1,2-dihydroquinazolin-4-one
C29H28N2O3S (484.18205380000006)
(6S,7S,8R)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
N-[(1R,3S,4aR,9aS)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
N-[(1R,3R,4aS,9aR)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
2-fluoro-N-[(2R,3S)-4-[(4-fluorophenyl)sulfonyl-[(2R)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
2-[(1S,3R,4aS,9aR)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1S,3S,4aR,9aS)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1S,3R,4aR,9aS)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
N-[(1S,3S,4aS,9aR)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
N-[(1R,3S,4aS,9aR)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b][1]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
2-fluoro-N-[(2S,3S)-4-[(4-fluorophenyl)sulfonyl-[(2R)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
2-fluoro-N-[(2S,3S)-4-[(4-fluorophenyl)sulfonyl-[(2S)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
2-[(2S,5R,6S)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(2R,5R,6S)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(2R,5R,6R)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(2S,5R,6R)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(1R,3S,4aR,9aS)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1R,3R,4aS,9aR)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1R,3S,4aS,9aR)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
N-[(1R,3R,4aR,9aS)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
N-[(1S,3R,4aR,9aS)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
2-fluoro-N-[(2S,3R)-4-[(4-fluorophenyl)sulfonyl-[(2R)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
2-fluoro-N-[(2R,3R)-4-[(4-fluorophenyl)sulfonyl-[(2R)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
1-[(1S)-1-ethylsulfonyl-1-(hydroxymethyl)-7-methoxy-2-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3-azetidine]yl]-2-(2-pyridinyl)ethanone
C24H28N4O5S (484.17803180000004)
(6R,7S,8R)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
[(1R)-1-(hydroxymethyl)-7-methoxy-2-methylsulfonyl-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]-pyridin-4-ylmethanone
C24H28N4O5S (484.17803180000004)
(6R,7S,8S)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7R,8S)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
2-[(2R,5S,6R)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(2S,5S,6R)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(2S,5S,6S)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(2R,5S,6S)-6-(hydroxymethyl)-5-[(1-methyl-4-imidazolyl)sulfonylamino]-2-oxanyl]-N-(4-phenylphenyl)acetamide
C24H28N4O5S (484.17803180000004)
2-[(1R,3R,4aR,9aS)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
2-[(1S,3S,4aS,9aR)-1-(hydroxymethyl)-6-[(2-methoxy-1-oxoethyl)amino]-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-3-yl]-N-(1,3-benzodioxol-5-ylmethyl)acetamide
N-[(1S,3R,4aS,9aR)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
N-[(1S,3S,4aR,9aS)-3-[2-[(4-chlorophenyl)methylamino]-2-oxoethyl]-1-(hydroxymethyl)-3,4,4a,9a-tetrahydro-1H-pyrano[3,4-b]benzofuran-6-yl]-2-cyclopropylacetamide
C26H29ClN2O5 (484.17648940000004)
2-fluoro-N-[(2R,3S)-4-[(4-fluorophenyl)sulfonyl-[(2S)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
2-fluoro-N-[(2R,3R)-4-[(4-fluorophenyl)sulfonyl-[(2S)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
2-fluoro-N-[(2S,3R)-4-[(4-fluorophenyl)sulfonyl-[(2S)-1-hydroxypropan-2-yl]amino]-2-methoxy-3-methylbutyl]-N-methylbenzamide
1-[(1R)-1-ethylsulfonyl-1-(hydroxymethyl)-7-methoxy-2-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,3-azetidine]yl]-2-(2-pyridinyl)ethanone
C24H28N4O5S (484.17803180000004)
(6S,7R,8S)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
[(1S)-1-(hydroxymethyl)-7-methoxy-2-methylsulfonyl-1-spiro[3,9-dihydro-1H-pyrido[3,4-b]indole-4,4-piperidine]yl]-pyridin-4-ylmethanone
C24H28N4O5S (484.17803180000004)
(6S,7R,8R)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7S,8S)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7R,8R)-4-[(4-fluorophenyl)-oxomethyl]-8-(hydroxymethyl)-7-[4-[2-(4-methoxyphenyl)ethynyl]phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
6-[2,2-Dimethyl-6-(3-oxo-3-phenylpropyl)chromen-5-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
(1S,2R,7S,13R,14R,16S,19S,20S)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docos-10-ene-5,12,17-trione
UK-3A
A lactone which is 9-methyl-1,5-dioxonane-2,6-dione substituted by a benzyl group at position 8, a [(3-hydroxy-pyridine-2-yl)carbonyl]amino group at position 3 and an isobutyryloxy group at position 7. It is isolated from the mycelia cake of Streptomyces sp. 517-02 and exhibits potent antifungal activity.
neosartoricin
A carbotricyclic compound obtained from the pathogenic fungi Aspergillus fumigatus and Neosartorya fischeri following activation of their polycyclic polyketide prenyltransferase (pcPTase)-containing silent clusters. It exhibits T-cell antiproliferative activity with an IC50 of 3 muM, suggesting a possible physiological role as an immunosuppressive agent.
n-[(3s,7r,8r,9s)-7-benzyl-9-methyl-8-[(2-methylpropanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl]-3-hydroxypyridine-2-carboximidic acid
8-{4-hydroxy-2-[2-(3-hydroxyphenyl)ethyl]-6-methoxyphenyl}-7-methoxy-9,10-dihydrophenanthrene-2,5-diol
(1s,2r,3r,4r,7s,8e,12s,13s,14s)-14-(acetyloxy)-9-(chloromethyl)-2,3-dihydroxy-4,13,17-trimethyl-5-oxo-6-oxatricyclo[11.4.0.0³,⁷]heptadeca-8,16-dien-12-yl acetate
C24H33ClO8 (484.18638480000004)
7-methoxy-6-[(1s,6r)-6-[(1e)-2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl]chromen-2-one
10-amino-3-[10-amino-7-(3-hydroxypropyl)-11-oxo-2,7-diazatricyclo[6.3.1.0⁴,¹²]dodeca-1,3,5,8(12),9-pentaen-3-yl]-7-(3-hydroxypropyl)-2,7-diazatricyclo[6.3.1.0⁴,¹²]dodeca-1,3,5,8(12),9-pentaen-11-one
(1s,2r,15r,17s)-3,3,7,17,21-pentamethyl-4,12,18,26-tetraoxaheptacyclo[15.11.1.0²,¹⁵.0⁵,¹⁴.0⁶,¹¹.0¹⁹,²⁸.0²⁰,²⁵]nonacosa-5(14),6,8,10,19(28),20,22,24-octaene-13,27-dione
7-methoxy-8-{6-[(1e)-2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl}chromen-2-one
(1r,2r,15s,17s)-3,3,7,17,21-pentamethyl-4,12,18,26-tetraoxaheptacyclo[15.11.1.0²,¹⁵.0⁵,¹⁴.0⁶,¹¹.0¹⁹,²⁸.0²⁰,²⁵]nonacosa-5(14),6,8,10,19(28),20,22,24-octaene-13,27-dione
(1r,2r,7s,13r,14r,16s,19s,20s)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione
8-ethoxy-2,15-dioxapentacyclo[22.2.2.1³,⁷.1¹⁰,¹⁴.0¹⁶,²¹]triaconta-1(26),3(30),4,6,10,12,14(29),16,18,20,24,27-dodecaene-4,5,17-triol
7-methoxy-6-[(1s,6r)-6-[(1e)-2-(7-methoxy-2-oxochromen-6-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl]chromen-2-one
(1s,3r,4s,4as,4bs,8r,8as,9r,10ar)-3-(acetyloxy)-8-bromo-1-hydroxy-4-isopropyl-1,8a-dimethyl-5-methylidene-decahydro-2h-phenanthren-9-yl acetate
4-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)propyl]-5-[(1e)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
4'-(furan-3-yl)-4,4,5',9',12'-pentamethyl-3,3a-dihydro-3',10',14'-trioxaspiro[furo[3,2-c]pyran-2,13'-tetracyclo[7.4.1.0¹,⁶.0⁸,¹²]tetradecane]-2',6,11'-trione
6-({3,6-dihydroxy-5-[(4-hydroxyphenyl)methyl]-2,5-dihydropyrazin-2-yl}methyl)-6-hydroxy-5h,5ah-indolo[2,1-b]quinazolin-12-one
[(1s,2s)-1-carboxy-2-{1-[(3s,7r)-3-carboxy-9,10-dioxo-4,12-diazatetracyclo[6.5.2.0⁴,¹⁵.0¹¹,¹⁴]pentadeca-1(13),8(15),11(14)-trien-7-yl]imidazol-4-yl}-2-hydroxyethyl]trimethylazanium
[C23H26N5O7]+ (484.18321460000004)
3-(4-hydroxyphenyl)-n-[2-(5-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h-indol-3-yl)ethyl]prop-2-enimidic acid
7-{4-hydroxy-2-[2-(4-hydroxyphenyl)ethyl]-6-methoxyphenoxy}-2-methoxy-9,10-dihydrophenanthren-4-ol
7-{4-hydroxy-2-[2-(3-hydroxyphenyl)ethyl]-6-methoxyphenoxy}-2-methoxy-9,10-dihydrophenanthren-4-ol
[1-carboxy-2-(1-{3-carboxy-9,10-dioxo-4,12-diazatetracyclo[6.5.2.0⁴,¹⁵.0¹¹,¹⁴]pentadeca-1(13),8(15),11(14)-trien-7-yl}imidazol-4-yl)-2-hydroxyethyl]trimethylazanium
[C23H26N5O7]+ (484.18321460000004)
(1's,2s,3ar,4'r,5'r,8'r,9'r,12'r)-4'-(furan-3-yl)-4,4,5',9',12'-pentamethyl-3,3a-dihydro-3',10',14'-trioxaspiro[furo[3,2-c]pyran-2,13'-tetracyclo[7.4.1.0¹,⁵.0⁸,¹²]tetradecane]-2',6,11'-trione
(1r,2r,7s,13r,14r,16s,19r,20s)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione
(2r,2ar,3r,4s,4ar,7r,7as,7br)-2a,4,7-trihydroxy-3-(hydroxymethyl)-6,6,7b-trimethyl-octahydrocyclobuta[e]inden-2-yl 3-chloro-6-hydroxy-4-methoxy-2-methylbenzoate
C24H33ClO8 (484.18638480000004)
7-methoxy-8-{6-[2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-4,6-dimethylcyclohex-2-en-1-yl}chromen-2-one
7-methoxy-8-[(1r,4r,6r)-6-[(1e)-2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-4,6-dimethylcyclohex-2-en-1-yl]chromen-2-one
7-{2-hydroxy-4-[2-(3-hydroxyphenyl)ethyl]-6-methoxyphenoxy}-2-methoxy-9,10-dihydrophenanthren-4-ol
3-{4-hydroxy-2-[2-(3-hydroxyphenyl)ethyl]-6-methoxyphenyl}-7-methoxy-9,10-dihydrophenanthrene-2,5-diol
4-[(1r)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)propyl]-5-[(1e)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
7-methoxy-6-{6-[2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl}chromen-2-one
n-{7-benzyl-9-methyl-8-[(2-methylpropanoyl)oxy]-2,6-dioxo-1,5-dioxonan-3-yl}-3-hydroxypyridine-2-carboximidic acid
1-[(1s,4s,4as,6r,8as)-4-(acetyloxy)-6-bromo-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-3-hydroxy-3-methylpent-4-en-2-yl acetate
(1r,6r,7r,10s,11s,14s,16r,17r,18s)-11-(furan-3-yl)-18-hydroxy-6,10,17,20,20-pentamethyl-2,12,15,19-tetraoxahexacyclo[16.2.1.0¹,⁶.0⁷,¹⁷.0¹⁰,¹⁶.0¹⁴,¹⁶]henicos-4-ene-3,13,21-trione
19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione
(3s,3ar,4s,9ar,9bs)-3-(acetyloxy)-3,6,9-trimethyl-2,7-dioxo-3ah,4h,5h,9ah,9bh-azuleno[4,5-b]furan-4-yl 3,4-dimethoxybenzoate
(1s,2r,15s,17s)-3,3,7,17,21-pentamethyl-4,12,18,26-tetraoxaheptacyclo[15.11.1.0²,¹⁵.0⁵,¹⁴.0⁶,¹¹.0¹⁹,²⁸.0²⁰,²⁵]nonacosa-5(14),6,8,10,19(28),20,22,24-octaene-13,27-dione
7-(acetyloxy)-9-[4-(acetyloxy)-3-methoxyphenyl]-6-methoxy-1h,3h,3ah,4h,9h,9ah-naphtho[2,3-c]furan-4-yl acetate
[(3ar,4s,6ar,8s,9r,9as,9bs)-8,9-dihydroxy-3,6-dimethylidene-4-[(2-methylprop-2-enoyl)oxy]-2-oxo-octahydroazuleno[4,5-b]furan-9-yl]methyl 4-hydroxybenzoate
(2e)-3-{4-[2-(acetyloxy)-5-[(1e)-3-(acetyloxy)prop-1-en-1-yl]-3-methoxyphenoxy]-3-methoxyphenyl}prop-2-en-1-yl acetate
11-(furan-3-yl)-18-hydroxy-6,10,17,20,20-pentamethyl-2,12,15,19-tetraoxahexacyclo[16.2.1.0¹,⁶.0⁷,¹⁷.0¹⁰,¹⁶.0¹⁴,¹⁶]henicos-4-ene-3,13,21-trione
7-methoxy-6-[(1r,6s)-6-[(1e)-2-(7-methoxy-2-oxochromen-6-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl]chromen-2-one
3-{4-[2-(acetyloxy)-5-[3-(acetyloxy)prop-1-en-1-yl]-3-methoxyphenoxy]-3-methoxyphenyl}prop-2-en-1-yl acetate
(2e)-3-(4-hydroxyphenyl)-n-[2-(5-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1h-indol-3-yl)ethyl]prop-2-enimidic acid
7-methoxy-6-{6-[(1z)-2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl}chromen-2-one
7-methoxy-6-{6-[(1e)-2-(7-methoxy-2-oxochromen-6-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl}chromen-2-one
(5as,6r)-6-{[(2s,5s)-3,6-dihydroxy-5-[(4-hydroxyphenyl)methyl]-2,5-dihydropyrazin-2-yl]methyl}-6-hydroxy-5h,5ah-indolo[2,1-b]quinazolin-12-one
{8,9-dihydroxy-3,6-dimethylidene-4-[(2-methylprop-2-enoyl)oxy]-2-oxo-octahydroazuleno[4,5-b]furan-9-yl}methyl 4-hydroxybenzoate
5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phenyl-3-{[(2s,3s,4s,5s,6r)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}chromen-4-one
(2s,3r)-3,6,8,9-tetrahydroxy-3-(2-hydroxy-4-oxopent-2-en-1-yl)-10-(3-methylbut-2-en-1-yl)-1-oxo-2,4-dihydroanthracen-2-yl acetate
3,3,7,17,21-pentamethyl-4,12,18,26-tetraoxaheptacyclo[15.11.1.0²,¹⁵.0⁵,¹⁴.0⁶,¹¹.0¹⁹,²⁸.0²⁰,²⁵]nonacosa-5(14),6,8,10,19(28),20,22,24-octaene-13,27-dione
3-{2-hydroxy-4-[2-(3-hydroxyphenyl)ethyl]-6-methoxyphenyl}-7-methoxy-9,10-dihydrophenanthrene-2,5-diol
14-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-15-oxa-1,11-diazahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹¹,²⁰.0¹³,¹⁸]docosa-2,4,6,8(21),16-pentaen-22-one
2-[(2e)-1-hydroxybut-2-en-2-yl]-11-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6h,7h,12h-indolo[2,3-a]quinolizin-4-one
5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phenyl-3-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]chromen-4-one
(8s)-8-ethoxy-2,15-dioxapentacyclo[22.2.2.1³,⁷.1¹⁰,¹⁴.0¹⁶,²¹]triaconta-1(26),3(30),4,6,10,12,14(29),16,18,20,24,27-dodecaene-4,5,17-triol
3-(acetyloxy)-8-bromo-1-hydroxy-4-isopropyl-1,8a-dimethyl-5-methylidene-decahydro-2h-phenanthren-9-yl acetate
(1r,2r,15r,17s)-3,3,7,17,21-pentamethyl-4,12,18,26-tetraoxaheptacyclo[15.11.1.0²,¹⁵.0⁵,¹⁴.0⁶,¹¹.0¹⁹,²⁸.0²⁰,²⁵]nonacosa-5(14),6,8,10,19(28),20,22,24-octaene-13,27-dione
7-methoxy-6-[(1r,6r)-6-[(1e)-2-(7-methoxy-2-oxochromen-8-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl]chromen-2-one
(8r)-8-ethoxy-2,15-dioxapentacyclo[22.2.2.1³,⁷.1¹⁰,¹⁴.0¹⁶,²¹]triaconta-1(26),3(30),4,6,10,12,14(29),16,18,20,24,27-dodecaene-4,5,17-triol
7-methoxy-6-{6-[2-(7-methoxy-2-oxochromen-6-yl)ethenyl]-3,6-dimethylcyclohex-2-en-1-yl}chromen-2-one
(1s,2r,3r,4r,7s,8e,12r,13s,14s)-14-(acetyloxy)-9-(chloromethyl)-2,3-dihydroxy-4,13,17-trimethyl-5-oxo-6-oxatricyclo[11.4.0.0³,⁷]heptadeca-8,16-dien-12-yl acetate
C24H33ClO8 (484.18638480000004)
2-(1-hydroxybut-2-en-2-yl)-11-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6h,7h,12h-indolo[2,3-a]quinolizin-4-one
(13r,14r)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione
(3as,4s,9s,9ar)-7-(acetyloxy)-9-[4-(acetyloxy)-3-methoxyphenyl]-6-methoxy-1h,3h,3ah,4h,9h,9ah-naphtho[2,3-c]furan-4-yl acetate
4-[3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)propyl]-5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
(1s,2r,7s,13r,14r,16r,20s)-19-(furan-3-yl)-11-hydroxy-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.0²,⁷.0²,¹⁰.0¹⁴,¹⁶.0¹⁴,²⁰]docos-10-ene-5,12,17-trione
4-(7-hydroxy-4-oxo-2-phenyl-2,3-dihydro-1-benzopyran-8-yl)-2,2-dimethyloxolan-3-yl 3-phenylprop-2-enoate
14-(acetyloxy)-9-(chloromethyl)-2,3-dihydroxy-4,13,17-trimethyl-5-oxo-6-oxatricyclo[11.4.0.0³,⁷]heptadeca-8,16-dien-12-yl acetate
C24H33ClO8 (484.18638480000004)