Exact Mass: 471.1502
Exact Mass Matches: 471.1502
Found 14 metabolites which its exact mass value is equals to given mass value 471.1502,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
10-Formyldihydrofolate
10-Formyldihydrofolate is a folate compound that has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells. The origin of 10-formyldihydrofolate remains an enigma. Its appearance only in the extracts from MTX-treated cells is not consistent with a simple oxidation of lO-formyl-H4folate during the extraction procedure. This, however, does not exclude the occurrence of spontaneous oxidation of 10-formyl-H4folate within the intact cells prior to the folate extraction. (PMID: 3366769) [HMDB] 10-formyldihydrofolate is a folate compound that has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells. The origin of 10-formyldihydrofolate remains an enigma. Its appearance only in the extracts from MTX-treated cells is not consistent with a simple oxidation of lO-formyl-H4folate during the extraction procedure. This, however, does not exclude the occurrence of spontaneous oxidation of 10-formyl-H4folate within the intact cells prior to the folate extraction. (PMID: 3366769).
5-formyl-tetrahydrofolate
5-formyl-tetrahydrofolate is a member of the class of compounds known as tetrahydrofolic acids. Tetrahydrofolic acids are heterocyclic compounds based on the 5,6,7,8-tetrahydropteroic acid skeleton conjugated with at least one L-glutamic acid unit. 5-formyl-tetrahydrofolate is practically insoluble (in water) and a weakly acidic compound (based on its pKa). 5-formyl-tetrahydrofolate can be found in a number of food items such as fennel, greenthread tea, orange mint, and coriander, which makes 5-formyl-tetrahydrofolate a potential biomarker for the consumption of these food products.
Citrovorum factor
D020011 - Protective Agents > D000931 - Antidotes D018977 - Micronutrients > D014815 - Vitamins
5-Formyltetrahydrofolate(2-)
COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS
(6S)-5-formyltetrahydrofolate(2-)
A dicarboxylic acid dianion arising from deprotonation of both carboxylic acid groups of (6S)-5-formyltetrahydrofolic acid.
5-Formyltetrahydrofolate(2-)
A dicarboxylic acid dianion obtained by deprotonation of the carboxy groups of 5-formyltetrahydrofolic acid.
10-Formyltetrahydrofolic acid
A form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-formyltetrahydrofolic acid is used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.
10-formyltetrahydrofolate(2-)
Dianion of 10-formyltetrahydrofolic acid arising from deprotonation of both carboxylic acid functions.
