Citrovorum factor (BioDeep_00000897313)
代谢物信息卡片
Citrovorum factor
化学式: C20H21N7O7-2 (471.1502396)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-]
InChI: InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/p-2/t12-,13-/m0/s1
描述信息
D020011 - Protective Agents > D000931 - Antidotes
D018977 - Micronutrients > D014815 - Vitamins
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Weiran Cao, Xue Zhang, Rui Li, Zijie Li, An Lu, Fei Yu, Lu Sun, Jiancheng Wang, Zhiyu Wang, Huining He. Lipid core-shell nanoparticles co-deliver FOLFOX regimen and siPD-L1 for synergistic targeted cancer treatment.
Journal of controlled release : official journal of the Controlled Release Society.
2024 Apr; 368(?):52-65. doi:
10.1016/j.jconrel.2024.02.025. [PMID: 38368946] - Carlos Lopez-Blazquez, Carlos Lacalle-Gonzalez, Lara Sanz-Criado, Michael Ochieng' Otieno, Jesus Garcia-Foncillas, Javier Martinez-Useros. Iron-Dependent Cell Death: A New Treatment Approach against Pancreatic Ductal Adenocarcinoma.
International journal of molecular sciences.
2023 Oct; 24(19):. doi:
10.3390/ijms241914979. [PMID: 37834426] - Da-Tong Ju, Rwei-Fen S Huang, Bruce Chi-Kang Tsai, Yi-Chen Su, Ping-Ling Chiu, Yung-Ming Chang, V Vijaya Padma, Tsung-Jung Ho, Chun-Hsu Yao, Wei-Wen Kuo, Chih-Yang Huang. Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways.
Neurotoxicity research.
2023 Sep; ?(?):. doi:
10.1007/s12640-023-00666-z. [PMID: 37707697] - Gérard Milano, Federico Innocenti, Hironobu Minami. Liposomal irinotecan (Onivyde): Exemplifying the benefits of nanotherapeutic drugs.
Cancer science.
2022 Jul; 113(7):2224-2231. doi:
10.1111/cas.15377. [PMID: 35445479] - Andrew B Nixon, Alexander B Sibley, Yingmiao Liu, Ace J Hatch, Chen Jiang, Flora Mulkey, Mark D Starr, John C Brady, Donna Niedzwiecki, Alan P Venook, Luis Baez-Diaz, Heinz-Josef Lenz, Bert H O'Neil, Federico Innocenti, Jeffrey A Meyerhardt, Eileen M O'Reilly, Kouros Owzar, Herbert I Hurwitz. Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance).
Clinical cancer research : an official journal of the American Association for Cancer Research.
2022 07; 28(13):2779-2788. doi:
10.1158/1078-0432.ccr-21-2389. [PMID: 34965954] - Chih-Yang Huang, Yi-Chen Su, Cheng-You Lu, Ping-Ling Chiu, Yung-Ming Chang, Da-Tong Ju, Ray-Jade Chen, Liang-Yo Yang, Tsung-Jung Ho, Hui-Chuan Kao. Edible folic acid and medicinal folinic acid produce cardioprotective effects in late-stage triple-transgenic Alzheimer's disease model mice by suppressing cardiac hypertrophy and fibrosis.
Environmental toxicology.
2022 Jul; 37(7):1740-1749. doi:
10.1002/tox.23521. [PMID: 35286012] - Y Sunakawa, H Satake, J Usher, Y Jaimes, Y Miyamoto, M Nakamura, M Kataoka, M Shiozawa, A Takagane, T Terazawa, T Watanabe, K Ishiguro, C Tanaka, M Takeuchi, M Fujii, K Danenberg, P V Danenberg, H-J Lenz, T Sekikawa, W Ichikawa. Dynamic changes in RAS gene status in circulating tumour DNA: a phase II trial of first-line FOLFOXIRI plus bevacizumab for RAS-mutant metastatic colorectal cancer (JACCRO CC-11).
ESMO open.
2022 06; 7(3):100512. doi:
10.1016/j.esmoop.2022.100512. [PMID: 35688061] - Ajana Pathikkal, Bijesh Puthusseri, Peethambaran Divya, Sudha Rudrappa, Vikas Singh Chauhan. Folate derivatives, 5-methyltetrahydrofolate and 10-formyltetrahydrofolate, protect BEAS-2B cells from high glucose-induced oxidative stress and inflammation.
In vitro cellular & developmental biology. Animal.
2022 May; 58(5):419-428. doi:
10.1007/s11626-022-00691-w. [PMID: 35678985] - Naveen Kr Dubey. Sensitive and rapid simultaneous quantitation of leucovorin and its major active metabolite 5-methyl-tetrahydrofolate in human plasma using a liquid chromatography coupled with triple quadruple mass spectrometry.
Biomedical chromatography : BMC.
2022 Apr; 36(4):e5299. doi:
10.1002/bmc.5299. [PMID: 34913177] - Marc Ghannoum, Darren M Roberts, David S Goldfarb, Jesper Heldrup, Kurt Anseeuw, Tais F Galvao, Thomas D Nolin, Robert S Hoffman, Valery Lavergne, Paul Meyers, Sophie Gosselin, Tudor Botnaru, Karine Mardini, David M Wood. Extracorporeal Treatment for Methotrexate Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
Clinical journal of the American Society of Nephrology : CJASN.
2022 04; 17(4):602-622. doi:
10.2215/cjn.08030621. [PMID: 35236714] - Luca Bedon, Erika Cecchin, Emanuele Fabbiani, Michele Dal Bo, Angela Buonadonna, Maurizio Polano, Giuseppe Toffoli. Machine Learning Application in a Phase I Clinical Trial Allows for the Identification of Clinical-Biomolecular Markers Significantly Associated With Toxicity.
Clinical pharmacology and therapeutics.
2022 03; 111(3):686-696. doi:
10.1002/cpt.2511. [PMID: 34905217] - Yves Menezo, Kay Elder, Arthur Clement, Patrice Clement. Folic Acid, Folinic Acid, 5 Methyl TetraHydroFolate Supplementation for Mutations That Affect Epigenesis through the Folate and One-Carbon Cycles.
Biomolecules.
2022 01; 12(2):. doi:
10.3390/biom12020197. [PMID: 35204698] - Akkarach Bumrungpert, Patcharanee Pavadhgul, Theera Piromsawasdi, M R Mozafari. Efficacy and Safety of Ferrous Bisglycinate and Folinic Acid in the Control of Iron Deficiency in Pregnant Women: A Randomized, Controlled Trial.
Nutrients.
2022 Jan; 14(3):. doi:
10.3390/nu14030452. [PMID: 35276810] - Taro Shibuki, Toshihiko Mizuta, Mototsugu Shimokawa, Futa Koga, Yujiro Ueda, Junichi Nakazawa, Azusa Komori, Satoshi Otsu, Shiho Arima, Masaru Fukahori, Akitaka Makiyama, Hiroki Taguchi, Takuya Honda, Kenji Mitsugi, Kenta Nio, Yasushi Ide, Norio Ureshino, Tsuyoshi Shirakawa, Taiga Otsuka. Prognostic nomogram for patients with unresectable pancreatic cancer treated with gemcitabine plus nab-paclitaxel or FOLFIRINOX: A post-hoc analysis of a multicenter retrospective study in Japan (NAPOLEON study).
BMC cancer.
2022 Jan; 22(1):19. doi:
10.1186/s12885-021-09139-y. [PMID: 34980029] - Riitta Niinimäki, Henri Aarnivala, Joanna Banerjee, Tytti Pokka, Kaisa Vepsäläinen, Arja Harila-Saari. Reduced dose folinic acid rescue after rapid high-dose methotrexate clearance is not associated with increased toxicity in a pediatric cohort.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2022 Jan; 30(1):127-133. doi:
10.1007/s00520-021-06395-3. [PMID: 34235555] - Tarek M Mostafa, Mohamed A Alm El-Din, Amira R Rashdan. Celecoxib as an adjuvant to chemotherapy for patients with metastatic colorectal cancer: A randomized controlled clinical study.
Saudi medical journal.
2022 Jan; 43(1):37-44. doi:
10.15537/smj.2022.43.1.20210574. [PMID: 35022282] - Sang-A Kim, Hyejoo Park, Kui-Jin Kim, Ji-Won Kim, Ji Hea Sung, Milang Nam, Ju Hyun Lee, Eun Hee Jung, Koung Jin Suh, Ji Yun Lee, Se Hyun Kim, Jeong-Ok Lee, Jin Won Kim, Yu Jung Kim, Jee Hyun Kim, Soo-Mee Bang, Jong Seok Lee, Keun-Wook Lee. Amphiregulin can predict treatment resistance to palliative first-line cetuximab plus FOLFIRI chemotherapy in patients with RAS wild-type metastatic colorectal cancer.
Scientific reports.
2021 12; 11(1):23803. doi:
10.1038/s41598-021-03197-9. [PMID: 34893673] - Muhammad Usman Minhas, Orva Abdullah, Muhammad Sohail, Ikrima Khalid, Sarfaraz Ahmad, Kifayat Ullah Khan, Syed Faisal Badshah. Synthesis of novel combinatorial drug delivery system (nCDDS) for co-delivery of 5-fluorouracil and leucovorin calcium for colon targeting and controlled drug release.
Drug development and industrial pharmacy.
2021 Dec; 47(12):1952-1965. doi:
10.1080/03639045.2022.2072514. [PMID: 35502653] - Gen Tsujio, Kazuya Muguruma, Shimpei Eguchi, Yasuhito Iseki, Yuichiro Miki, Mami Yoshii, Tatsunari Fukuoka, Tatsuro Tamura, Masatsune Shibutani, Hisashi Nagahara, Takahiro Toyokawa, Hiroaki Tanaka, Shigeru Lee, Masakazu Yashiro, Masaichi Ohira. [A Case of Hyperammonemic Encephalopathy following mFOLFOX6 plus Panitumumab Therapy for Rectal Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
2021 Dec; 48(13):2073-2075. doi:
NULL. [PMID: 35045497] - Shaimaa M Sallam, Eman Shawky, Samah M El Sohafy. Determination of the effect of germination on the folate content of the seeds of some legumes using HPTLC-mass spectrometry-multivariate image analysis.
Food chemistry.
2021 Nov; 362(?):130206. doi:
10.1016/j.foodchem.2021.130206. [PMID: 34082289] - Kiran Bharat Lokhande, Sayali Doiphode, Renu Vyas, K Venkateswara Swamy. Molecular docking and simulation studies on SARS-CoV-2 Mpro reveals Mitoxantrone, Leucovorin, Birinapant, and Dynasore as potent drugs against COVID-19.
Journal of biomolecular structure & dynamics.
2021 11; 39(18):7294-7305. doi:
10.1080/07391102.2020.1805019. [PMID: 32815481] - Yanyan Zhang, Lihao Jiang, Ju Ouyang, Xianfeng Du, Longlong Jiang. Efficacy and safety of traditional Chinese medicine injections combined with FOLFOX4 regimen for gastric cancer: A protocol for systematic review and network meta-analysis.
Medicine.
2021 Oct; 100(41):e27525. doi:
10.1097/md.0000000000027525. [PMID: 34731143] - Weichao Li, Qiuju Liang, Ratnesh Chandra Mishra, Raul Sanchez-Mu Oz, Huan Wang, Xin Chen, Dominique Van Der Straeten, Chunyi Zhang, Youli Xiao. The 5-formyl-tetrahydrofolate proteome links folates with C/N metabolism and reveals feedback regulation of folate biosynthesis.
The Plant cell.
2021 10; 33(10):3367-3385. doi:
10.1093/plcell/koab198. [PMID: 34352110] - Fleur van der Sijde, Marjolein Y V Homs, Marlies L van Bekkum, Thierry P P van den Bosch, Koop Bosscha, Marc G Besselink, Bert A Bonsing, Jan Willem B de Groot, Thomas M Karsten, Bas Groot Koerkamp, Brigitte C M Haberkorn, Saskia A C Luelmo, Leonie J M Mekenkamp, Dana A M Mustafa, Johanna W Wilmink, Casper H J van Eijck, Eveline E Vietsch, On Behalf Of The Dutch Pancreatic Cancer Group. Serum miR-373-3p and miR-194-5p Are Associated with Early Tumor Progression during FOLFIRINOX Treatment in Pancreatic Cancer Patients: A Prospective Multicenter Study.
International journal of molecular sciences.
2021 Oct; 22(20):. doi:
10.3390/ijms222010902. [PMID: 34681562] - Frank A Sinicrope, Qian Shi, Thomas C Smyrk, Richard M Goldberg, Steven J Cohen, Sharlene Gill, Morton S Kahlenberg, Suresh Nair, Anthony F Shield, Balkrishna N Jahagirdar, Sawyer B Jacobson, Nathan R Foster, Michael N Pollak, Steven R Alberts. Association of Adiponectin and Vitamin D With Tumor Infiltrating Lymphocytes and Survival in Stage III Colon Cancer.
JNCI cancer spectrum.
2021 10; 5(5):. doi:
10.1093/jncics/pkab070. [PMID: 34485815] - Ian J Cohen. Acute renal injury after high-dose methotrexate is independent of folinic acid dose.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2021 Oct; 29(10):5557-5558. doi:
10.1007/s00520-021-06389-1. [PMID: 34176019] - Atul Batra, Patricia A Tang, Winson Y Cheung. Prognostic Significance of Disease Control at 12 Weeks in Patients With Advanced Pancreatic Cancer Receiving FOLFIRINOX as First-line Chemotherapy.
American journal of clinical oncology.
2021 10; 44(10):519-525. doi:
10.1097/coc.0000000000000856. [PMID: 34366400] - Aline Reetz Conceição, Deisi Nara Belucik, Lilian Missio, Luiz Gustavo Brenner, Matheus Henrique Monteiro, Kleber Silva Ribeiro, Deise Fialho Costa, Maria Clara da Silva Valadão, Alessandra Gonçalves Commodaro, João Rafael de Oliveira Dias, Rubens Belfort. Ocular Findings in Infants with Congenital Toxoplasmosis after a Toxoplasmosis Outbreak.
Ophthalmology.
2021 09; 128(9):1346-1355. doi:
10.1016/j.ophtha.2021.03.009. [PMID: 33711379] - Jason N Barreto, Kristen T Peterson, Erin F Barreto, Kristin C Mara, Ross A Dierkhising, Nelson Leung, Thomas E Witzig, Carrie A Thompson. Early, empiric high-dose leucovorin rescue in lymphoma patients treated with sequential doses of high-dose methotrexate.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2021 Sep; 29(9):5293-5301. doi:
10.1007/s00520-021-06106-y. [PMID: 33661366] - R De Luca, C Volpe, O Mistretta, R Paci, G Ferrera, V Caputo, G Rosati, G Cicero. NEPA (netupitant/palonosetron) for the antiemetic prophylaxis of nausea and vomiting induced by chemotherapy (CINV) with Folfirinox and Folfoxiri even during the COVID-19 pandemic: a real-life study.
European review for medical and pharmacological sciences.
2021 08; 25(16):5310-5317. doi:
10.26355/eurrev_202108_26552. [PMID: 34486707] - Yaman Göksel, Kinga Zor, Tomas Rindzevicius, Bodil Elise Thorhauge Als-Nielsen, Kjeld Schmiegelow, Anja Boisen. Quantification of Methotrexate in Human Serum Using Surface-Enhanced Raman Scattering-Toward Therapeutic Drug Monitoring.
ACS sensors.
2021 07; 6(7):2664-2673. doi:
10.1021/acssensors.1c00643. [PMID: 34143600] - Angela Lamarca, Daniel H Palmer, Harpreet Singh Wasan, Paul J Ross, Yuk Ting Ma, Arvind Arora, Stephen Falk, Roopinder Gillmore, Jonathan Wadsley, Kinnari Patel, Alan Anthoney, Anthony Maraveyas, Tim Iveson, Justin S Waters, Claire Hobbs, Safia Barber, W David Ryder, John Ramage, Linda M Davies, John A Bridgewater, Juan W Valle. Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial.
The Lancet. Oncology.
2021 05; 22(5):690-701. doi:
10.1016/s1470-2045(21)00027-9. [PMID: 33798493] - Olivia Jones, Xiaoqian Cheng, Saravana R K Murthy, Lawan Ly, Taisen Zhuang, Giacomo Basadonna, Michael Keidar, Jerome Canady. The synergistic effect of Canady Helios cold atmospheric plasma and a FOLFIRINOX regimen for the treatment of cholangiocarcinoma in vitro.
Scientific reports.
2021 04; 11(1):8967. doi:
10.1038/s41598-021-88451-w. [PMID: 33903679] - S Bernard, L Hachon, J F Diasonama, C Madaoui, L Aguinaga, E Miekoutima, H Moatti, Emeline Perrial, I Madelaine, P Brice, Catherine Thieblemont. Ambulatory high-dose methotrexate administration as central nervous system prophylaxis in patients with aggressive lymphoma.
Annals of hematology.
2021 Apr; 100(4):979-986. doi:
10.1007/s00277-020-04341-7. [PMID: 33608849] - Akihiro Fujisawa, Hidenori Takahara, Yuhei Kondo, Masatoshi Akagami, Tadashi Yokoyama, Noriko Takahara. [A Case of Liver Metastasis of Colorectal Cancer in a Hemodialysis Patient, Underwent Liver Resection and Chemotherapy after Colorectal Resection].
Gan to kagaku ryoho. Cancer & chemotherapy.
2021 Apr; 48(4):552-554. doi:
NULL. [PMID: 33976045] - Young Hoon Choi, Sang Hyub Lee, Min Su You, Bang Sup Shin, Woo Hyun Paik, Ji Kon Ryu, Yong-Tae Kim, Wooil Kwon, Jin-Young Jang, Sun-Whe Kim. Prognostic Factors for Patients with Borderline Resectable or Locally Advanced Pancreatic Cancer Receiving Neoadjuvant FOLFIRINOX.
Gut and liver.
2021 Mar; 15(2):315-323. doi:
10.5009/gnl19182. [PMID: 32235008] - Zhonghua Ouyang, Jing Huang, Yi Ren, Huanhuan Li, Yao Ding, Ke Zhang, Lei Jiang, Peng Yu. Studies on the intracellular accumulation process of methotrexate and its correlation with the key protein using an LC-MS/MS method: a novel way to realize prospective individualized medication.
Analytical and bioanalytical chemistry.
2021 Mar; 413(7):1799-1807. doi:
10.1007/s00216-020-03125-2. [PMID: 33564926] - Mustafa Gürbüz, Erman Akkuş, Güngör Utkan. Topical aloe vera for the treatment of cetuximab-related acneiform rash in colorectal cancer: A case report.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2021 Mar; 27(2):480-484. doi:
10.1177/1078155220937751. [PMID: 32623964] - Akitomo Yokokawa, Shun Kaneko, Sayuri Endo, Yuki Minowa, Hideaki Ayukawa, Ryohei Hirano, Fumio Nagashima, Daisuke Naruge, Naohiro Okano, Takaaki Kobayashi, Kirio Kawai, Junji Furuse, Takashi Furuta, Hiromi Shibasaki. Effect of UGT1A1, CYP3A and CES Activities on the Pharmacokinetics of Irinotecan and its Metabolites in Patients with UGT1A1 Gene Polymorphisms.
European journal of drug metabolism and pharmacokinetics.
2021 Mar; 46(2):317-324. doi:
10.1007/s13318-021-00675-3. [PMID: 33619631] - Ken Shiraiwa, Yosuke Suzuki, Hiroki Uchida, Yukio Iwashita, Ryota Tanaka, Motoshi Iwao, Kazuhiro Tada, Teijiro Hirashita, Takashi Masuda, Yuichi Endo, Masafumi Inomata, Hiroki Itoh. Simultaneous quantification method for 5-FU, uracil, and tegafur using UPLC-MS/MS and clinical application in monitoring UFT/LV combination therapy after hepatectomy.
Scientific reports.
2021 02; 11(1):3132. doi:
10.1038/s41598-021-82908-8. [PMID: 33542452] - Motofumi Maruta, Takanori Miyoshi, Naomi Matsuo, Takuya Yamashina, Kenji Irie, Minako Tsuruta, Hiroko Tsukada, Moeko Tsuruyama, Masahisa Nagano, Yoichi Hiraki. Clinical pharmacokinetics of oxaliplatin in a hemodialysis patient with advanced gastric cancer.
Journal of chemotherapy (Florence, Italy).
2021 Feb; 33(1):51-55. doi:
10.1080/1120009x.2020.1728861. [PMID: 32066346] - Jianfeng Guo, Zhuo Yu, Dandan Sun, Yifang Zou, Yun Liu, Leaf Huang. Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma.
Molecular cancer.
2021 01; 20(1):10. doi:
10.1186/s12943-020-01297-0. [PMID: 33407548] - Catherine R Hanna, Kathleen A Boyd, Joanna Wincenciak, Janet Graham, Timothy Iveson, Robert J Jones, Richard Wilson. Do clinical trials change practice? A longitudinal, international assessment of colorectal cancer prescribing practices.
Cancer treatment and research communications.
2021; 28(?):100445. doi:
10.1016/j.ctarc.2021.100445. [PMID: 34425469] - Daxin Huang, Qingliang Lin, Jianyuan Song, Benhua Xu. Prognostic Value of Pretreatment Serum CA199 in Patients with Locally Advanced Rectal Cancer Treated with CRT Followed by TME with Normal Pretreatment Carcinoembryonic Antigen Levels.
Digestive surgery.
2021; 38(1):24-29. doi:
10.1159/000508442. [PMID: 33171467] - Szu-Jung Chen, Li-Hsien Chen, Yu-Min Yeh, Chou-Ching K Lin, Peng-Chan Lin, Han-Wei Huang, Meng-Ru Shen, Bo-Wen Lin, Jeng-Chang Lee, Cheng-Che Lee, Yueh-Feng Lee, Huai-Chueh Chiang, Jang-Yang Chang. Targeting lysosomal cysteine protease cathepsin S reveals immunomodulatory therapeutic strategy for oxaliplatin-induced peripheral neuropathy.
Theranostics.
2021; 11(10):4672-4687. doi:
10.7150/thno.54793. [PMID: 33754020] - Jessica Boyce, Karine Tawagi, John T Cole. Primary colon adenocarcinoma with choriocarcinoma differentiation: a case report and review of the literature.
Journal of medical case reports.
2020 Nov; 14(1):220. doi:
10.1186/s13256-020-02544-0. [PMID: 33190644] - Natalia I Krupenko, Jaspreet Sharma, Peter Pediaditakis, Kristi L Helke, Madeline S Hall, Xiuxia Du, Susan Sumner, Sergey A Krupenko. Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder.
Human genomics.
2020 11; 14(1):41. doi:
10.1186/s40246-020-00291-3. [PMID: 33168096] - Himani Dhingra, Manas Kalra, Amita Mahajan. Safe administration of high-dose methotrexate with minimal drug level monitoring: Experience from a center in north India.
Pediatric blood & cancer.
2020 11; 67(11):e28394. doi:
10.1002/pbc.28394. [PMID: 32813334] - Nilgun Yildirim, Mahir Cengiz. Predictive clinical factors of chronic peripheral neuropathy induced by oxaliplatin.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer.
2020 Oct; 28(10):4781-4788. doi:
10.1007/s00520-020-05319-x. [PMID: 31974772] - Javier Sastre, Virginia de la Orden, Antonio Martínez, Inmaculada Bando, Milagros Balbín, Beatriz Bellosillo, Sarai Palanca, Maria Isabel Peligros Gomez, Beatriz Mediero, Patricia Llovet, Virginia Moreno Moral, José Maria Viéitez, Pilar García-Alfonso, Silvia Gil Calle, Maria José Ortiz-Morales, Antonieta Salud, Guillermo Quintero, Carlos Lopez, Eduardo Díaz-Rubio, Enrique Aranda. Association Between Baseline Circulating Tumor Cells, Molecular Tumor Profiling, and Clinical Characteristics in a Large Cohort of Chemo-naïve Metastatic Colorectal Cancer Patients Prospectively Collected.
Clinical colorectal cancer.
2020 09; 19(3):e110-e116. doi:
10.1016/j.clcc.2020.02.014. [PMID: 32278676] - Angela Damato, Francesco Iachetta, Lorenzo Antonuzzo, Guglielmo Nasti, Francesca Bergamo, Roberto Bordonaro, Evaristo Maiello, Alberto Zaniboni, Giuseppe Tonini, Alessandra Romagnani, Annalisa Berselli, Nicola Normanno, Carmine Pinto. Phase II study on first-line treatment of NIVolumab in combination with folfoxiri/bevacizumab in patients with Advanced COloRectal cancer RAS or BRAF mutated - NIVACOR trial (GOIRC-03-2018).
BMC cancer.
2020 Aug; 20(1):822. doi:
10.1186/s12885-020-07268-4. [PMID: 32867715] - Elliot M Frohman, Nicole R Villemarette-Pittman, Roberto Alejandro Cruz, Reid Longmuir, Vernon Rowe, Elizabeth S Rowe, Thomas C Varkey, Lawrence Steinman, Scott S Zamvil, Teresa C Frohman. Part II. high-dose methotrexate with leucovorin rescue for severe COVID-19: An immune stabilization strategy for SARS-CoV-2 induced 'PANIC' attack.
Journal of the neurological sciences.
2020 08; 415(?):116935. doi:
10.1016/j.jns.2020.116935. [PMID: 32534807] - Takeshi Yamada, Akihisa Matsuda, Goro Takahashi, Takuma Iwai, Kohki Takeda, Kohji Ueda, Sho Kuriyama, Michihiro Koizumi, Seiichi Shinji, Yasuyuki Yokoyama, Ryo Ohta, Hiroshi Yoshida. Emerging RAS, BRAF, and EGFR mutations in cell-free DNA of metastatic colorectal patients are associated with both primary and secondary resistance to first-line anti-EGFR therapy.
International journal of clinical oncology.
2020 Aug; 25(8):1523-1532. doi:
10.1007/s10147-020-01691-0. [PMID: 32394048] - Changhoon Yoo, Sang Soo Lee, Ki Byung Song, Jae Ho Jeong, Jaewon Hyung, Do Hyun Park, Tae Jun Song, Dong Wan Seo, Sung Koo Lee, Myung-Hwan Kim, Seung Soo Lee, Jin Hee Kim, Hyung-Seung Jin, Jin-Hong Park, Dae Wook Hwang, Jae Hoon Lee, Woohyung Lee, Heung-Moon Chang, Kyu-Pyo Kim, Baek-Yeol Ryoo, Song Cheol Kim. Neoadjuvant modified FOLFIRINOX followed by postoperative gemcitabine in borderline resectable pancreatic adenocarcinoma: a Phase 2 study for clinical and biomarker analysis.
British journal of cancer.
2020 08; 123(3):362-368. doi:
10.1038/s41416-020-0867-x. [PMID: 32433600] - Alberto Bongiovanni, Chiara Liverani, Sara Pusceddu, Silvana Leo, Giovanni Di Meglio, Stefano Tamberi, Daniele Santini, Fabio Gelsomino, Francesca Pucci, Rossana Berardi, Ivan Lolli, Francesca Bergamo, Sergio Ricci, Flavia Foca, Stefano Severi, Toni Ibrahim. Randomised phase II trial of CAPTEM or FOLFIRI as SEcond-line therapy in NEuroendocrine CArcinomas and exploratory analysis of predictive role of PET/CT imaging and biological markers (SENECA trial): a study protocol.
BMJ open.
2020 07; 10(7):e034393. doi:
10.1136/bmjopen-2019-034393. [PMID: 32690499] - Ruwan Parakrama, Elisha Fogel, Carol Chandy, Titto Augustine, Matt Coffey, Lydia Tesfa, Sanjay Goel, Radhashree Maitra. Immune characterization of metastatic colorectal cancer patients post reovirus administration.
BMC cancer.
2020 Jun; 20(1):569. doi:
10.1186/s12885-020-07038-2. [PMID: 32552875] - Radu Vidra, Raluca Bodea, Voicu Mercea, Adina Nemes. Challenges of pancreatic cancer chemotherapy in the COVID-19 era.
Journal of gastrointestinal and liver diseases : JGLD.
2020 06; 29(2):273-275. doi:
10.15403/jgld-2527. [PMID: 32531001] - Stéphane Jaisson, Aurore Desmons, Antoine Braconnier, Alain Wynckel, Philippe Rieu, Philippe Gillery, Roselyne Garnotel. An unusually high plasma concentration of homocysteine resulting from a combination of so-called "secondary" etiologies.
Clinical biochemistry.
2020 Jun; 80(?):52-55. doi:
10.1016/j.clinbiochem.2020.03.010. [PMID: 32199937] - Laura L Meijer, Ingrid Garajová, Chiara Caparello, Tessa Y S Le Large, Adam E Frampton, Enrico Vasile, Niccola Funel, Geert Kazemier, Elisa Giovannetti. Plasma miR-181a-5p Downregulation Predicts Response and Improved Survival After FOLFIRINOX in Pancreatic Ductal Adenocarcinoma.
Annals of surgery.
2020 06; 271(6):1137-1147. doi:
10.1097/sla.0000000000003084. [PMID: 30394883] - Mouadh Barbirou, Ikram Sghaier, Sinda Bedoui, Rahma Ben Abderrazek, Hazar Kraiem, Azer Farah, Rym Hassiki, Amina Mokrani, Amel Mezlini, Wassim Y Almawi, Besma Loueslati-Yacoubi, Balkiss Bouhaouala-Zahar. KCNB1 gene polymorphisms and related indel as predictor biomarkers of treatment response for colorectal cancer - toward a personalized medicine.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2020 Jun; 42(6):1010428320925237. doi:
10.1177/1010428320925237. [PMID: 32484056] - Lucia Scarabel, Marica Garziera, Sara Fortuna, Fioretta Asaro, Giuseppe Toffoli, Silvano Geremia. Soluble HLA-G expression levels and HLA-G/irinotecan association in metastatic colorectal cancer treated with irinotecan-based strategy.
Scientific reports.
2020 05; 10(1):8773. doi:
10.1038/s41598-020-65424-z. [PMID: 32471996] - Yun-Yun Yang, Lei Gao, Nan Ding, Xue-Bin Wang, Li-Peng Zhang, Li-Hong Gao, Zhuo Wang. How to rescue high-dose methotrexate induced nephrotoxicity and literature review about hemodiafiltration?.
Pakistan journal of pharmaceutical sciences.
2020 May; 33(3):1163-1167. doi:
. [PMID: 33191243] - Jianfeng Guo, Zhuo Yu, Manisit Das, Leaf Huang. Nano Codelivery of Oxaliplatin and Folinic Acid Achieves Synergistic Chemo-Immunotherapy with 5-Fluorouracil for Colorectal Cancer and Liver Metastasis.
ACS nano.
2020 04; 14(4):5075-5089. doi:
10.1021/acsnano.0c01676. [PMID: 32283007] - Wei Wang, Yan Zhang, Lu Zhang, Chen Yang, Jun Feng, Huacong Cai, Miao Chen, Xinxin Cao, Junling Zhuang, Tienan Zhu, Minghui Duan, Wei Zhang, Jian Li, Daobin Zhou. Intravenous methotrexate at a dose of 1 g/m2 incorporated into RCHOP prevented CNS relapse in high-risk DLBCL patients: A prospective, historic controlled study.
American journal of hematology.
2020 04; 95(4):E80-E83. doi:
10.1002/ajh.25723. [PMID: 31925808] - Sakura Hiraide, Keigo Komine, Yuko Sato, Kota Ouchi, Hiroo Imai, Ken Saijo, Masahiro Takahashi, Shin Takahashi, Hidekazu Shirota, Masanobu Takahashi, Chikashi Ishioka. Efficacy of modified FOLFOX6 chemotherapy for patients with unresectable pseudomyxoma peritonei.
International journal of clinical oncology.
2020 Apr; 25(4):774-781. doi:
10.1007/s10147-019-01592-x. [PMID: 31823151] - Maike Zimmermann, Tao Li, Thomas J Semrad, Chun-Yi Wu, Aiming Yu, George Cimino, Michael Malfatti, Kurt Haack, Kenneth W Turteltaub, Chong-Xian Pan, May Cho, Edward J Kim, Paul T Henderson. Oxaliplatin-DNA Adducts as Predictive Biomarkers of FOLFOX Response in Colorectal Cancer: A Potential Treatment Optimization Strategy.
Molecular cancer therapeutics.
2020 04; 19(4):1070-1079. doi:
10.1158/1535-7163.mct-19-0133. [PMID: 32029633] - Rubén Pampín, Yoar Labeaga, Belén Rodríguez, Beatriz Fernández, Rubén Fernández, Mónica Carbajales. Experience with ambulatory high-dose methotrexate administration as CNS prophylaxis in patients with non-Hodgkin lymphoma.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2020 Apr; 26(3):549-555. doi:
10.1177/1078155219852412. [PMID: 31156052] - A Surinach, T Phung, O Abdul-Rahim, M Khushman. Prolonged response to liposomal irinotecan in a patient with stage IV pancreatic/bile duct cancer previously treated with FOLFIRINOX and gemcitabine plus nab-paclitaxel.
Current oncology (Toronto, Ont.).
2020 04; 27(2):e222-e225. doi:
10.3747/co.27.5893. [PMID: 32489272] - Joel Horacio Elizondo-Luevano, Julia Verde-Star, Azucena González-Horta, Rocío Castro-Ríos, Magda Elizabeth Hernández-García, Abelardo Chávez-Montes. In Vitro Effect of Methanolic Extract of Argemone mexicana against Trichomonas vaginalis.
The Korean journal of parasitology.
2020 Apr; 58(2):135-145. doi:
10.3347/kjp.2020.58.2.135. [PMID: 32418382] - Johanna C Bendell, Tamara Sauri, Antonio Cubillo Gracián, Rafael Alvarez, Carlos López-López, Pilar García-Alfonso, Maen Hussein, Maria-Luisa Limon Miron, Andrés Cervantes, Clara Montagut, Cristina Santos Vivas, Alberto Bessudo, Patricia Plezia, Veerle Moons, Johannes Andel, Jaafar Bennouna, Andre van der Westhuizen, Leslie Samuel, Simona Rossomanno, Christophe Boetsch, Angelika Lahr, Izolda Franjkovic, Florian Heil, Katharina Lechner, Oliver Krieter, Herbert Hurwitz. The McCAVE Trial: Vanucizumab plus mFOLFOX-6 Versus Bevacizumab plus mFOLFOX-6 in Patients with Previously Untreated Metastatic Colorectal Carcinoma (mCRC).
The oncologist.
2020 03; 25(3):e451-e459. doi:
10.1634/theoncologist.2019-0291. [PMID: 32162804] - Eric Van Cutsem, Caroline Paccard, Marielle Chiron, Josep Tabernero. Impact of Prior Bevacizumab Treatment on VEGF-A and PlGF Levels and Outcome Following Second-Line Aflibercept Treatment: Biomarker Post Hoc Analysis of the VELOUR Trial.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2020 02; 26(3):717-725. doi:
10.1158/1078-0432.ccr-19-1985. [PMID: 31727675] - Jia Gang Han, Zhen Jun Wang, Wei Gen Zeng, Yan Bin Wang, Guang Hui Wei, Zhi Wei Zhai, Bao Cheng Zhao, Bing Qiang Yi. Efficacy and safety of self-expanding metallic stent placement followed by neoadjuvant chemotherapy and scheduled surgery for treatment of obstructing left-sided colonic cancer.
BMC cancer.
2020 Jan; 20(1):57. doi:
10.1186/s12885-020-6560-x. [PMID: 31992260] - Alexander Hendricks, Philip Rosenstiel, Sebastian Hinz, Greta Burmeister, Christoph Röcken, Kathrin Boersch, Clemens Schafmayer, Thomas Becker, Andre Franke, Michael Forster. Rapid response of stage IV colorectal cancer with APC/TP53/KRAS mutations to FOLFIRI and Bevacizumab combination chemotherapy: a case report of use of liquid biopsy.
BMC medical genetics.
2020 01; 21(1):3. doi:
10.1186/s12881-019-0941-5. [PMID: 31900123] - Aamod S Dekhne, Changwen Ning, Md Junayed Nayeen, Khushbu Shah, Hasini Kalpage, Josephine Frühauf, Adrianne Wallace-Povirk, Carrie O'Connor, Zhanjun Hou, Seongho Kim, Maik Hüttemann, Aleem Gangjee, Larry H Matherly. Cellular Pharmacodynamics of a Novel Pyrrolo[3,2-d]pyrimidine Inhibitor Targeting Mitochondrial and Cytosolic One-Carbon Metabolism.
Molecular pharmacology.
2020 01; 97(1):9-22. doi:
10.1124/mol.119.117937. [PMID: 31707355] - Charlotte M A Lubout, Susanna M I Goorden, Karin van den Hurk, Bregje Jaeger, Nynke G L Jager, Silvana van Koningsbruggen, Malika Chegary, Clara D M van Karnebeek. Successful Treatment of Hereditary Folate Malabsorption With Intramuscular Folinic Acid.
Pediatric neurology.
2020 01; 102(?):62-66. doi:
10.1016/j.pediatrneurol.2019.06.009. [PMID: 31371121] - Hyunkyung Park, Ju-Hee Bang, Ah-Rong Nam, Ji Eun Park, Mei Hua Jin, Yung-Jue Bang, Do-Youn Oh. The prognostic role of soluble TGF-beta and its dynamics in unresectable pancreatic cancer treated with chemotherapy.
Cancer medicine.
2020 01; 9(1):43-51. doi:
10.1002/cam4.2677. [PMID: 31701645] - Chia-Hsun Hsieh, Chien-Yu Lin, Cheng-Lung Hsu, Kang-Hsing Fan, Shiang-Fu Huang, Chun-Ta Liao, Li-Yu Lee, Shu-Kung Ng, Tzu-Chen Yen, Joseph Tung-Chieh Chang, Jr-Rung Lin, Hung-Ming Wang. Incorporation of Astragalus polysaccharides injection during concurrent chemoradiotherapy in advanced pharyngeal or laryngeal squamous cell carcinoma: preliminary experience of a phase II double-blind, randomized trial.
Journal of cancer research and clinical oncology.
2020 Jan; 146(1):33-41. doi:
10.1007/s00432-019-03033-8. [PMID: 31728618] - Xiaoling Fu, Yanbo Zhang, Lisheng Chang, Dengcheng Hui, Ru Jia, Ningning Liu, Huayue Zhang, Gang Han, Zhifen Han, Yuan Li, Hui Liu, Huirong Zhu, Qi Li. The JPJDF has Synergistic Effect with Fluoropyrimidine in the Maintenance Therapy for Metastatic Colorectal Cancer.
Recent patents on anti-cancer drug discovery.
2020; 15(3):257-269. doi:
10.2174/1574892815666200717141205. [PMID: 32679021] - Tadashi Yokoyama, Hiroshi Makino, Atsushi Hirakata, Junji Ueda, Hideyuki Takata, Mikihiro Okusa, Manpei Kawashima, Takeshi Tsujino, Masaru Hosone, Akira Matsushita, Yoshiharu Nakamura, Hiroshi Yoshida. Conversion Surgery for Metastatic Pancreatic Mucinous Carcinoma Responsive to Systemic Chemotherapy with Modified FOLFIRINOX: A Case Report.
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi.
2019 Dec; 86(5):284-290. doi:
10.1272/jnms.jnms.2019_86-502. [PMID: 31105119] - Tatsushi Shingai, Takayuki Fukuzaki, Shumpei Okimura, Yoshiro Ito, Yoshiki Taniguchi, Tadafumi Fukata, Hisashi Nishida, Osamu Takayama, Setsuko Yoshioka, Shigeyuki Hojo, Hiroaki Ohigashi. [A Case of Nephrotic Syndrome Induced by FOLFIRI plus Ramucirumab for Metastatic Descending Colon Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
2019 Dec; 46(13):2155-2157. doi:
NULL. [PMID: 32156863] - Weiguang Qiang, Qinqin Wu, Xuefeng Ni, Chu Zhang, Jiemin Zhao. Emergence of KRAS p.G13D mutation and acquired resistance to cetuximab in colorectal cancer with vulvar metastasis: A case report.
Medicine.
2019 Dec; 98(50):e18423. doi:
10.1097/md.0000000000018423. [PMID: 31852167] - Thijs Oude Munnink, Alex van der Meer, Jacco de Haan, Daan Touw, Michel van Kruchten. Reversible Impaired Methotrexate Clearance After Platinum-Based Chemotherapy for Osteosarcoma.
Therapeutic drug monitoring.
2019 12; 41(6):693-695. doi:
10.1097/ftd.0000000000000662. [PMID: 31169759] - Yanshuo Cao, Qing Chang, Wenjiang Zhang, Olga Ornatsky, David Hedley, Eric X Chen. Skin platinum deposition in colorectal cancer patients following oxaliplatin-based therapy.
Cancer chemotherapy and pharmacology.
2019 Dec; 84(6):1195-1200. doi:
10.1007/s00280-019-03956-6. [PMID: 31520102] - Heather L Huelster, Melissa M S Hogan, Matthew J Resnick. Acute Renal Transplant Failure Secondary to an Obstructing Ileal Conduit Adenocarcinoma: Case Report and Literature Review.
Urology.
2019 Dec; 134(?):39-41. doi:
10.1016/j.urology.2019.06.028. [PMID: 31276713] - Danping Wang, Xiaofei Li, Lingyan Xu, Wentong Fang, Xiaomin Cai, Ying Wang, Jiawei Wang, Yuanyuan Wang, Fengjiao Zhao, Yanhong Gu. Dose-escalation of oxaliplatin in hemodialysis patient treated with FOLFOX therapy: A case report.
Medicine.
2019 Nov; 98(44):e17462. doi:
10.1097/md.0000000000017462. [PMID: 31689749] - Tetsuya Hamaguchi, Tadamichi Denda, Toshihiro Kudo, Naotoshi Sugimoto, Takashi Ura, Kentaro Yamazaki, Hirofumi Fujii, Takeshi Kajiwara, Takako Eguchi Nakajima, Shin Takahashi, Satoshi Otsu, Yoshito Komatsu, Fumio Nagashima, Toshikazu Moriwaki, Taito Esaki, Takeo Sato, Michio Itabashi, Eiji Oki, Toru Sasaki, Marielle Chiron, Takayuki Yoshino. Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer.
Cancer science.
2019 Nov; 110(11):3565-3572. doi:
10.1111/cas.14198. [PMID: 31520559] - Katherine Domb, Danielle Keidar-Friedman, Khalil Kashkush. A novel miniature transposon-like element discovered in the coding sequence of a gene that encodes for 5-formyltetrahydrofolate in wheat.
BMC plant biology.
2019 Nov; 19(1):461. doi:
10.1186/s12870-019-2034-1. [PMID: 31675912] - Jihane Boustani, Eleonor Rivin Del Campo, Julie Blanc, Didier Peiffert, Karine Benezery, Renata Pereira, Emmanuel Rio, Elisabeth Le Prisé, Gilles Créhange, Florence Huguet. Quality Assurance of Dose-Escalated Radiation Therapy in a Randomized Trial for Locally Advanced Oesophageal cancer.
International journal of radiation oncology, biology, physics.
2019 10; 105(2):329-337. doi:
10.1016/j.ijrobp.2019.06.2542. [PMID: 31299242] - Elvira Grandone, Pasquale Martinelli, Michela Villani, Gennaro Vecchione, Lucia Fischetti, Angelica Leccese, Rosa Santacroce, Gaetano Corso, Maurizio Margaglione. Prospective evaluation of pregnancy outcome in an Italian woman with late-onset combined homocystinuria and methylmalonic aciduria.
BMC pregnancy and childbirth.
2019 Aug; 19(1):318. doi:
10.1186/s12884-019-2474-5. [PMID: 31470807] - Toshihiro Tanaka, Takeshi Sato, Hideyuki Nishiofuku, Tetsuya Masada, Shota Tatsumoto, Nagaaki Marugami, Toshio Otsuji, Masatoshi Kanno, Fumikazu Koyama, Masayuki Sho, Kimihiko Kichikawa. Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study.
BMC cancer.
2019 Aug; 19(1):758. doi:
10.1186/s12885-019-5862-3. [PMID: 31370815] - Masayuki Tanaka, Max Heckler, André L Mihaljevic, Huihui Sun, Ulla Klaiber, Ulrike Heger, Markus W Büchler, Thilo Hackert. CT response of primary tumor and CA19-9 predict resectability of metastasized pancreatic cancer after FOLFIRINOX.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.
2019 Aug; 45(8):1453-1459. doi:
10.1016/j.ejso.2019.03.039. [PMID: 30981446] - Hyunkyung Park, Ju-Hee Bang, Ah-Rong Nam, Ji Eun Park, Mei Hua Jin, Yung-Jue Bang, Do-Youn Oh. Prognostic implications of soluble programmed death-ligand 1 and its dynamics during chemotherapy in unresectable pancreatic cancer.
Scientific reports.
2019 07; 9(1):11131. doi:
10.1038/s41598-019-47330-1. [PMID: 31366979] - Lynne M Howells, Chinenye O O Iwuji, Glen R B Irving, Shaun Barber, Harriet Walter, Zahirah Sidat, Nicola Griffin-Teall, Rajinder Singh, Nalini Foreman, Samita R Patel, Bruno Morgan, William P Steward, Andreas Gescher, Anne L Thomas, Karen Brown. Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial.
The Journal of nutrition.
2019 07; 149(7):1133-1139. doi:
10.1093/jn/nxz029. [PMID: 31132111] - Gang Zhou, Jing Yang. Correlations of gastrointestinal hormones with inflammation and intestinal flora in patients with gastric cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology.
2019 Jul; 24(4):1595-1600. doi:
NULL. [PMID: 31646814] - Chenfeng Xu, Wenkai Hui, Lili Sun, Qianqian Gao, Qiaogen Zou. [Simultaneous determination of leucovorin and 5-methyl-tetrahydrofolate diastereoisomers in human plasma by high-performance liquid chromatography-tandem mass spectrometry coupled with ultrafiltration centrifugation-based pretreatment and its application to a pharmacokinetic study].
Se pu = Chinese journal of chromatography.
2019 Jun; 37(6):581-588. doi:
10.3724/sp.j.1123.2019.01008. [PMID: 31152507] - Wanming He, Bishan Liang, Chunlin Wang, Shaowei Li, Yang Zhao, Qiong Huang, Zexian Liu, Zhiqi Yao, Qijing Wu, Wangjun Liao, Shuyi Zhang, Yajing Liu, Yi Xiang, Jia Liu, Min Shi. MSC-regulated lncRNA MACC1-AS1 promotes stemness and chemoresistance through fatty acid oxidation in gastric cancer.
Oncogene.
2019 06; 38(23):4637-4654. doi:
10.1038/s41388-019-0747-0. [PMID: 30742067] - Lieselotte Lemoine, Elsy Thijssen, Robert Carleer, Karlien Geboers, Paul Sugarbaker, Kurt van der Speeten. Body surface area-based vs concentration-based perioperative intraperitoneal chemotherapy after optimal cytoreductive surgery in colorectal peritoneal surface malignancy treatment: COBOX trial.
Journal of surgical oncology.
2019 Jun; 119(7):999-1010. doi:
10.1002/jso.25437. [PMID: 30838646] - Aparna R Parikh, Fa-Chyi Lee, Linda Yau, Han Koh, James Knost, Edith P Mitchell, Ivan Bosanac, Nicholas Choong, Frank Scappaticci, Christoph Mancao, Heinz-Josef Lenz. MAVERICC, a Randomized, Biomarker-stratified, Phase II Study of mFOLFOX6-Bevacizumab versus FOLFIRI-Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2019 05; 25(10):2988-2995. doi:
10.1158/1078-0432.ccr-18-1221. [PMID: 30224341] - Zongcheng Li, Yuling Chen, W U Ren, Shuofeng Hu, Zhaoli Tan, Yan Wang, Yaowen Chen, Jian Zhang, Jiaqi Wu, Tingting Li, Jianming Xu, Xiaomin Ying. Transcriptome Alterations in Liver Metastases of Colorectal Cancer After Acquired Resistance to Cetuximab.
Cancer genomics & proteomics.
2019 May; 16(3):207-219. doi:
10.21873/cgp.20126. [PMID: 31018951]