Exact Mass: 469.2900194
Exact Mass Matches: 469.2900194
Found 346 metabolites which its exact mass value is equals to given mass value 469.2900194
,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Neomethymycin
C25H43NO7 (469.30393680000003)
A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.
Methymycin
C25H43NO7 (469.30393680000003)
A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.
ebastine
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1].
Ebastine
Ebastine (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood–brain barrier and thus allows an effective block of the H1 receptor in peripheral tissue without a central side effect, i. e not causing sedation or drowsiness. The basic patent for ebastine in Europe is EP-B-134124. It is often provided in micronised form, due to poor water solubility. (Wikipedia) CYP2J2, an arachidonic acid epoxygenase, is recognized for its role in the first-pass metabolism of astemizole and ebastine. (PMID: 22328583) R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1].
Artefenomel
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent D009676 - Noxae > D016877 - Oxidants > D010545 - Peroxides
Eflucimibe
C29H43NO2S (469.30143380000004)
Tert-Butyl 3-((3S,6S,12aS)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)propanoate
C26H35N3O5 (469.25765800000005)
tumonoic acid G
C25H43NO7 (469.30393680000003)
A natural product found particularly in Oscillatoria margaritifera and Oscillatoria margaritifera.
(8E,12E)-3-benzyl-15-sec-butyl-11-hydroxy-6,8,10,12,14-pentamethyl-1-oxa-4-azacyclopentadeca-8,12-diene-2,5-dione
C29H43NO4 (469.31919180000006)
12beta-acetoxyl-(25S)-22betaN-spirosol-4-en-3-one
C29H43NO4 (469.31919180000006)
Ser His Val Lys
C20H35N7O6 (469.26486900000003)
Hypaconine
A diterpene alkaloid with formula C24H39NO8, originally isolated from Aconitum carmichaeli. Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. Hypaconine?exhibits strong cardiac activity[1].
Ebastin
R - Respiratory system > R06 - Antihistamines for systemic use > R06A - Antihistamines for systemic use D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists C308 - Immunotherapeutic Agent > C29578 - Histamine-1 Receptor Antagonist CONFIDENCE standard compound; INTERNAL_ID 2512 COVID info from COVID-19 Disease Map Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; INTERNAL_ID 8493 Ebastine (LAS-W 090) is an orally active, second-generation histamine H1 receptor antagonist. Ebastine can be used for the symptoms of allergic rhinitis and chronic idiopathic urticaria research[1].
Glu Lys Pro Pro
C21H35N5O7 (469.25363600000003)
Glu Pro Lys Pro
C21H35N5O7 (469.25363600000003)
Glu Pro Pro Lys
C21H35N5O7 (469.25363600000003)
His Lys Ser Val
C20H35N7O6 (469.26486900000003)
His Lys Val Ser
C20H35N7O6 (469.26486900000003)
His Ser Lys Val
C20H35N7O6 (469.26486900000003)
His Ser Val Lys
C20H35N7O6 (469.26486900000003)
His Val Lys Ser
C20H35N7O6 (469.26486900000003)
His Val Ser Lys
C20H35N7O6 (469.26486900000003)
Ile Ile Lys Pro
C23H43N5O5 (469.32640280000004)
Ile Ile Pro Lys
C23H43N5O5 (469.32640280000004)
Ile Ile Pro Gln
Ile Ile Gln Pro
Ile Lys Ile Pro
C23H43N5O5 (469.32640280000004)
Ile Lys Leu Pro
C23H43N5O5 (469.32640280000004)
Ile Lys Pro Ile
C23H43N5O5 (469.32640280000004)
Ile Lys Pro Leu
C23H43N5O5 (469.32640280000004)
Ile Leu Lys Pro
C23H43N5O5 (469.32640280000004)
Ile Leu Pro Lys
C23H43N5O5 (469.32640280000004)
Ile Leu Pro Gln
Ile Leu Gln Pro
Ile Pro Ile Lys
C23H43N5O5 (469.32640280000004)
Ile Pro Ile Gln
Ile Pro Lys Ile
C23H43N5O5 (469.32640280000004)
Ile Pro Lys Leu
C23H43N5O5 (469.32640280000004)
Ile Pro Leu Lys
C23H43N5O5 (469.32640280000004)
Ile Pro Leu Gln
Ile Pro Gln Ile
Ile Pro Gln Leu
Ile Gln Ile Pro
Ile Gln Leu Pro
Ile Gln Pro Ile
Ile Gln Pro Leu
Lys Glu Pro Pro
C21H35N5O7 (469.25363600000003)
Lys His Ser Val
C20H35N7O6 (469.26486900000003)
Lys His Val Ser
C20H35N7O6 (469.26486900000003)
Lys Ile Ile Pro
C23H43N5O5 (469.32640280000004)
Lys Ile Leu Pro
C23H43N5O5 (469.32640280000004)
Lys Ile Pro Ile
C23H43N5O5 (469.32640280000004)
Lys Ile Pro Leu
C23H43N5O5 (469.32640280000004)
Lys Leu Ile Pro
C23H43N5O5 (469.32640280000004)
Lys Leu Leu Pro
C23H43N5O5 (469.32640280000004)
Lys Leu Pro Ile
C23H43N5O5 (469.32640280000004)
Lys Leu Pro Leu
C23H43N5O5 (469.32640280000004)
Lys Pro Glu Pro
C21H35N5O7 (469.25363600000003)
Lys Pro Ile Ile
C23H43N5O5 (469.32640280000004)
Lys Pro Ile Leu
C23H43N5O5 (469.32640280000004)
Lys Pro Leu Ile
C23H43N5O5 (469.32640280000004)
Lys Pro Leu Leu
C23H43N5O5 (469.32640280000004)
Lys Pro Pro Glu
C21H35N5O7 (469.25363600000003)
Lys Ser His Val
C20H35N7O6 (469.26486900000003)
Lys Ser Val His
C20H35N7O6 (469.26486900000003)
Lys Val His Ser
C20H35N7O6 (469.26486900000003)
Lys Val Ser His
C20H35N7O6 (469.26486900000003)
Leu Ile Lys Pro
C23H43N5O5 (469.32640280000004)
Leu Ile Pro Lys
C23H43N5O5 (469.32640280000004)
Leu Ile Pro Gln
Leu Ile Gln Pro
Leu Lys Ile Pro
C23H43N5O5 (469.32640280000004)
Leu Lys Leu Pro
C23H43N5O5 (469.32640280000004)
Leu Lys Pro Ile
C23H43N5O5 (469.32640280000004)
Leu Lys Pro Leu
C23H43N5O5 (469.32640280000004)
Leu Leu Lys Pro
C23H43N5O5 (469.32640280000004)
Leu Leu Pro Lys
C23H43N5O5 (469.32640280000004)
Leu Leu Pro Gln
Leu Leu Gln Pro
Leu Pro Ile Lys
C23H43N5O5 (469.32640280000004)
Leu Pro Ile Gln
Leu Pro Lys Ile
C23H43N5O5 (469.32640280000004)
Leu Pro Lys Leu
C23H43N5O5 (469.32640280000004)
Leu Pro Leu Lys
C23H43N5O5 (469.32640280000004)
Leu Pro Leu Gln
Leu Pro Gln Ile
Leu Pro Gln Leu
Leu Gln Ile Pro
Leu Gln Leu Pro
Leu Gln Pro Ile
Leu Gln Pro Leu
Pro Glu Lys Pro
C21H35N5O7 (469.25363600000003)
Pro Glu Pro Lys
C21H35N5O7 (469.25363600000003)
Pro Ile Ile Lys
C23H43N5O5 (469.32640280000004)
Pro Ile Ile Gln
Pro Ile Lys Ile
C23H43N5O5 (469.32640280000004)
Pro Ile Lys Leu
C23H43N5O5 (469.32640280000004)
Pro Ile Leu Lys
C23H43N5O5 (469.32640280000004)
Pro Ile Leu Gln
Pro Ile Gln Ile
Pro Ile Gln Leu
Pro Lys Glu Pro
C21H35N5O7 (469.25363600000003)
Pro Lys Ile Ile
C23H43N5O5 (469.32640280000004)
Pro Lys Ile Leu
C23H43N5O5 (469.32640280000004)
Pro Lys Leu Ile
C23H43N5O5 (469.32640280000004)
Pro Lys Leu Leu
C23H43N5O5 (469.32640280000004)
Pro Lys Pro Glu
C21H35N5O7 (469.25363600000003)
Pro Leu Ile Lys
C23H43N5O5 (469.32640280000004)
Pro Leu Ile Gln
Pro Leu Lys Ile
C23H43N5O5 (469.32640280000004)
Pro Leu Lys Leu
C23H43N5O5 (469.32640280000004)
Pro Leu Leu Lys
C23H43N5O5 (469.32640280000004)
Pro Leu Leu Gln
Pro Leu Gln Ile
Pro Leu Gln Leu
Pro Pro Glu Lys
C21H35N5O7 (469.25363600000003)
Pro Pro Lys Glu
C21H35N5O7 (469.25363600000003)
Pro Pro Arg Thr
C20H35N7O6 (469.26486900000003)
Pro Pro Thr Arg
C20H35N7O6 (469.26486900000003)
Pro Gln Ile Ile
Pro Gln Ile Leu
Pro Gln Leu Ile
Pro Gln Leu Leu
Pro Arg Pro Thr
C20H35N7O6 (469.26486900000003)
Pro Arg Thr Pro
C20H35N7O6 (469.26486900000003)
Pro Arg Val Val
Pro Thr Pro Arg
C20H35N7O6 (469.26486900000003)
Pro Thr Arg Pro
C20H35N7O6 (469.26486900000003)
Pro Val Arg Val
Pro Val Val Arg
Gln Ile Ile Pro
Gln Ile Leu Pro
Gln Ile Pro Ile
Gln Ile Pro Leu
Gln Leu Ile Pro
Gln Leu Leu Pro
Gln Leu Pro Ile
Gln Leu Pro Leu
Gln Pro Ile Ile
Gln Pro Ile Leu
Gln Pro Leu Ile
Gln Pro Leu Leu
Arg Pro Pro Thr
C20H35N7O6 (469.26486900000003)
Arg Pro Thr Pro
C20H35N7O6 (469.26486900000003)
Arg Pro Val Val
Arg Thr Pro Pro
C20H35N7O6 (469.26486900000003)
Arg Val Pro Val
Arg Val Val Pro
Ser His Lys Val
C20H35N7O6 (469.26486900000003)
Ser Lys His Val
C20H35N7O6 (469.26486900000003)
Ser Lys Val His
C20H35N7O6 (469.26486900000003)
Ser Val His Lys
C20H35N7O6 (469.26486900000003)
Ser Val Lys His
C20H35N7O6 (469.26486900000003)
Thr Pro Pro Arg
C20H35N7O6 (469.26486900000003)
Thr Pro Arg Pro
C20H35N7O6 (469.26486900000003)
Thr Arg Pro Pro
C20H35N7O6 (469.26486900000003)
Val His Lys Ser
C20H35N7O6 (469.26486900000003)
Val His Ser Lys
C20H35N7O6 (469.26486900000003)
Val Lys His Ser
C20H35N7O6 (469.26486900000003)
Val Lys Ser His
C20H35N7O6 (469.26486900000003)
Val Pro Arg Val
Val Pro Val Arg
Val Arg Pro Val
Val Arg Val Pro
Val Ser His Lys
C20H35N7O6 (469.26486900000003)
Val Ser Lys His
C20H35N7O6 (469.26486900000003)
Val Val Pro Arg
Val Val Arg Pro
cyclohexyl amide
C29H43NO4 (469.31919180000006)
2-[[4-[2-[4-(oxiran-2-ylmethoxy)phenyl]propan-2-yl]phenoxy]methyl]oxirane,2-piperazin-1-ylethanamine
Ko 143
C26H35N3O5 (469.25765800000005)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D054659 - Diketopiperazines Ko 143 is a potent and selective ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor. Ko 143 displays >200-fold selectivity over P-gp and MRP-1 transporters[1][2].
2-Dimethylaminoethyl-1,10-dimethyl-2,7-dihydrotetraphyllinate
tert-butyl 4-[4-[6-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]pyrazol-1-yl]piperidine-1-carboxylate
C24H36BN5O4 (469.28602060000003)
Dimethylaminoethyl reserpilinate dihydrochloride
C26H35N3O5 (469.25765800000005)
Tert-Butyl 3-((3S,6S,12aS)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)propanoate
C26H35N3O5 (469.25765800000005)
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D054659 - Diketopiperazines
(10S,13S)-13-(hydroxymethyl)-5-[(3R)-6-hydroxy-3,6,7-trimethyloct-1-en-3-yl]-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4,6,8(15)-tetraen-11-one
C28H43N3O3 (469.33042480000006)
(2S,4aS,6aS,6bR,10R,12aS)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
[3-carboxy-2-[(9Z,12E)-10-nitrooctadeca-9,12-dienoyl]oxypropyl]-trimethylazanium
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
Gln-Leu-Leu-Pro
A tetrapeptide composed of L-glutamine, two L-leucine units and L-proline joined in sequence by peptide linkages.
1alpha,6alpha,16beta-Trimethoxy-4-(methoxymethyl)-20-methylaconitane-8,13,14alpha,15alpha-tetrol
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-[[[3,4-dioxo-2-(1-pyrrolidinyl)-1-cyclobutenyl]amino]methyl]-1-cyclohexanecarboxamide
C26H35N3O5 (469.25765800000005)
N-[(4S,7S,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]pyrazine-2-carboxamide
C25H35N5O4 (469.26889100000005)
4-[[[(2S,3S)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
4-[[[(2R,3R)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
4-[[[(2S,3R)-10-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
(2R,3R)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
4-[[[(2S,3R)-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
(2S,3R)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
(2S,3R)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-10-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
N-[(4R,7S,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
N-[(4R,7R,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
N-[(4S,7R,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
3-methoxy-N-[(5S,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
3-methoxy-N-[(5R,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4S,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4S,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4R,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4R,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
N-[(5R,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
N-[(5S,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
N-[(5R,6S,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
4-methoxy-N-[(5R,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(5R,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
[(1R)-7-methoxy-9-methyl-1,2-bis(2-pyridinylmethyl)-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,3-azetidine]yl]methanol
1-[(1S)-1-(hydroxymethyl)-7-methoxy-9-methyl-1-[4-oxanyl(oxo)methyl]-2-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]ethanone
C26H35N3O5 (469.25765800000005)
4-[[[(2R,3R)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
4-[[[(2S,3S)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
(2S,3R)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
(2S,3S)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-8-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
(2R,3S)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
(2R,3R)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
(2R,3S)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-10-(dimethylamino)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
(2S,3S)-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-10-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-3,4-dihydro-2H-1,5-benzoxazocin-6-one
C26H35N3O5 (469.25765800000005)
4-[[[(2S,3R)-8-(dimethylamino)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl-methylamino]methyl]benzoic acid
C26H35N3O5 (469.25765800000005)
N-[(4R,7S,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
N-[(4R,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
N-[(4S,7R,8R)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
N-[(4S,7S,8S)-8-methoxy-4,7,10-trimethyl-11-oxo-5-propyl-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]-2-pyrazinecarboxamide
C25H35N5O4 (469.26889100000005)
3-methoxy-N-[(5R,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
3-methoxy-N-[(5S,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
3-methoxy-N-[(5S,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
3-methoxy-N-[(5S,6S,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
3-methoxy-N-[(5R,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4S,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4S,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4S,7R,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4R,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4R,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4R,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4S,7R,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4R,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
2-methoxy-N-[(4S,7S,8R)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(4R,7S,8S)-8-methoxy-4,5,7,10-tetramethyl-11-oxo-2-oxa-5,10-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
N-[(5S,6S,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
N-[(5R,6R,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
N-[(5S,6R,9R)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
N-[(5S,6R,9S)-5-methoxy-3,6,9-trimethyl-2-oxo-8-(5-pyrimidinylmethyl)-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]propanamide
C25H35N5O4 (469.26889100000005)
4-methoxy-N-[(5S,6R,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(5S,6S,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(5R,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(5S,6S,9R)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-methoxy-N-[(5S,6R,9S)-5-methoxy-3,6,8,9-tetramethyl-2-oxo-11-oxa-3,8-diazabicyclo[10.4.0]hexadeca-1(12),13,15-trien-14-yl]benzamide
C26H35N3O5 (469.25765800000005)
4-[[4-(dimethylamino)phenyl]-(4-phenyliminonaphthalen-1-ylidene)methyl]-N,N-dimethylaniline
2-Amino-3-[hydroxy-(2-hydroxy-3-tetradecanoyloxypropoxy)phosphoryl]oxypropanoic acid
C20H40NO9P (469.24405600000006)
2-[2,3-Di(trimethylsilyloxy)butoxy]-N-[2-(diethylamino)ethyl]-3-pyridinecarboxamide
1-tetradecanoyl-glycero-3-phosphoserine
C20H40NO9P (469.24405600000006)
1-(2-methoxy-hexadecanyl)-sn-glycero-3-phosphoethanolamine
1-(2-methoxy-14-methyl-pentadecanyl)-sn-glycero-3-phosphoethanolamine
1-(2-methoxy-13-methyl-pentadecanyl)-sn-glycero-3-phosphoethanolamine
MRT199665
MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively[1]. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells[2]. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370[3].
n-[2-(4-{[(2e)-6-(acetyloxy)-4,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}phenyl)ethyl]benzenecarboximidic acid
C27H35NO6 (469.24642500000004)
(1s,2r,3r,4s,5r,6s,8r,9s,10s,13s,16s,17r,18s)-11-ethyl-9-hydroperoxy-4,6,16,18-tetramethoxy-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-8,13-diol
4-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-12-(1-hydroxyethyl)-3,5,7,11-tetramethyl-1-oxacyclododec-9-ene-2,8-dione
C25H43NO7 (469.30393680000003)
(2r,3r,4s,5s,6r,7r,8r,13r,14r,16s,17s,18r)-11-ethyl-6,18-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,7,8,14,16-pentol
(3s,3ar,4s,5s,6s,6ar,10s,12r,15r,15as)-3-benzyl-4,5,10,12-tetramethyl-3h,3ah,5h,6h,6ah,9h,10h,11h,15h-cycloundeca[d]isoindole-1,4,6,12,15-pentol
(2s)-1-(3-{[(2s,5s)-3,6-dihydroxy-5-methyl-2,5-dihydropyrazin-2-yl]methyl}-2-(2-methylbut-3-en-2-yl)-1h-indol-5-yl)-3-hydroxy-3-methylbutan-2-yl acetate
C26H35N3O5 (469.25765800000005)
9-chloro-n-(5-ethyl-5-methyl-2-oxofuran-3-yl)-3,10-dihydroxyoctadeca-4,6-dienimidic acid
C25H40ClNO5 (469.2594860000001)
n-[2-(4-{[(2e)-4-(acetyloxy)-6,7-dihydroxy-3,7-dimethyloct-2-en-1-yl]oxy}phenyl)ethyl]benzenecarboximidic acid
C27H35NO6 (469.24642500000004)
(1r,3ar,3bs,7s,9ar,9br,11r,11as)-1-acetyl-3a,3b,7-trihydroxy-9a,11a-dimethyl-1h,2h,3h,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-11-yl pyridine-3-carboxylate
C27H35NO6 (469.24642500000004)
(3e,5e,7e,15z,17e,19e,21e,23z)-9,19,26-trimethyl-1-azacyclohexacosa-1,3,5,7,15,17,19,21,23-nonaene-2,10,11,12,14-pentol
2-{[(2r,3s)-3-methyl-2-[(2s)-1-[(2s)-2-methyldecanoyl]pyrrolidine-2-carbonyloxy]pentanoyl]oxy}propanoic acid
C25H43NO7 (469.30393680000003)
2-[(2e,5e,7e,11e,13e)-10-hydroxy-3,5,7,9,11,13-hexamethylpentadeca-2,5,7,11,13-pentaen-1-yl]-5,6-dimethoxy-3-methylpyridin-4-ol
C29H43NO4 (469.31919180000006)
(2r,4s,4ar,5s,6e,8as)-5-[(3r,4s)-5-hydroxy-4-[(3s)-oct-1-en-3-yl]-2-oxo-3,4-dihydropyrrole-3-carbonyl]-4-methyl-6-propylidene-2,3,4,4a,5,8a-hexahydro-1h-naphthalene-2-carboxylic acid
10-chloro-n-(5-ethyl-5-methyl-2-oxofuran-3-yl)-3,9-dihydroxyoctadeca-4,6-dienimidic acid
C25H40ClNO5 (469.2594860000001)
2-({3-methyl-2-[1-(2-methyldecanoyl)pyrrolidine-2-carbonyloxy]pentanoyl}oxy)propanoic acid
C25H43NO7 (469.30393680000003)
(1s,2r,3r,4s,5s,6s,8r,9s,10s,13s,16s,17r,18s,19s)-11-ethyl-6,18-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,8,9,16,19-pentol
(1r,2s,3s,4s,5s,6s,8r,9r,10s,13r,14r,16r,17s)-11-ethyl-6,16-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,5,8,14,17-pentol
n-[(3-methoxy-4-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl]-8-methylnonanimidic acid
3-(acetyloxy)-5,7-dimethyl-12-methylidene-10,16-dioxo-7-azahexacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-4-yl 2-methylpropanoate
C27H35NO6 (469.24642500000004)
4-[(1e)-3-({4-[(3-aminopropyl)amino]butyl}[(2e)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-yl]amino)prop-1-en-1-yl]-2-methoxyphenol
(3r,4z,6e)-10-chloro-n-[(5s)-5-ethyl-5-methyl-2-oxofuran-3-yl]-3,9-dihydroxyoctadeca-4,6-dienimidic acid
C25H40ClNO5 (469.2594860000001)
n-{2-[4-(2-{5-[2-(acetyloxy)propan-2-yl]-2-methyloxolan-2-yl}-2-hydroxyethoxy)phenyl]ethyl}benzenecarboximidic acid
C27H35NO6 (469.24642500000004)
2-(10-hydroxy-3,5,7,9,11,13-hexamethylpentadeca-2,5,7,11,13-pentaen-1-yl)-5,6-dimethoxy-3-methylpyridin-4-ol
C29H43NO4 (469.31919180000006)
3,26-dihydroxy-9,9,16,16-tetramethyl-24-oxo-8-oxa-14,23,25-triazaheptacyclo[17.5.2.0¹,¹⁷.0³,¹⁵.0⁴,¹³.0⁷,¹².0¹⁹,²³]hexacosa-10,14,25-trien-14-ium-14-olate
C26H35N3O5 (469.25765800000005)
n-(2-{4-[(2r)-2-[(2s,5s)-5-[2-(acetyloxy)propan-2-yl]-2-methyloxolan-2-yl]-2-hydroxyethoxy]phenyl}ethyl)benzenecarboximidic acid
C27H35NO6 (469.24642500000004)
(1s)-1-[(1r,2s,10r,12r,13r)-16-[(5r,6r)-3,5-dimethyl-5,6-dihydroindolizin-6-yl]-4,13,15-trimethyl-11-oxa-3,14-diazapentacyclo[8.8.0.0²,¹².0³,⁷.0¹⁴,¹⁸]octadeca-4,6,8,15,17-pentaen-10-yl]ethanol
(1r,3s,4s,5r,8r,9s,11s,14r,17s,18r)-3-(acetyloxy)-5,7-dimethyl-12-methylidene-10,16-dioxo-7-azahexacyclo[9.6.2.0¹,⁸.0⁵,¹⁷.0⁹,¹⁴.0¹⁴,¹⁸]nonadecan-4-yl 2-methylpropanoate
C27H35NO6 (469.24642500000004)
(3e,5e,8r,10s,12r,13e,15z,17e,19e,21e,23e)-7,19,26-trimethyl-1-azacyclohexacosa-1,3,5,13,15,17,19,21,23-nonaene-2,8,9,10,12-pentol
(1s,2r,3r,7r,10s,14r)-2-{3-[(1s,4r,5s)-1,4-dimethyl-2,8-dioxabicyclo[3.2.1]octan-4-yl]-3-oxopropyl}-14-isopropyl-12-azapentacyclo[8.6.0.0²,¹³.0³,⁷.0⁷,¹¹]hexadec-12-en-12-ium-12-olate
C29H43NO4 (469.31919180000006)
n-[(3-methoxy-4-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phenyl)methyl]-8-methylnonanimidic acid
11-ethyl-9-hydroperoxy-4,6,16,18-tetramethoxy-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-8,13-diol
(1r,2r,3as,3bs,7s,9ar,9bs,11as)-7-hydroxy-9a,11a-dimethyl-1-[(1s)-1-[(5r)-5-methyl-4-oxo-5,6-dihydro-3h-pyridin-2-yl]ethyl]-1h,2h,3h,3ah,3bh,4h,6h,7h,8h,9h,9bh,10h,11h-cyclopenta[a]phenanthren-2-yl acetate
C29H43NO4 (469.31919180000006)
(1s,2s,3s,4s,5r,6r,8s,9s,10s,13s,16s,17r,18r,19s)-11-ethyl-6,18-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,8,9,16,19-pentol
(3r,4z,6e)-9-chloro-n-[(5s)-5-ethyl-5-methyl-2-oxofuran-3-yl]-3,10-dihydroxyoctadeca-4,6-dienimidic acid
C25H40ClNO5 (469.2594860000001)
(1r,2r,3r,4r,5r,6s,8r,9r,10r,13r,16r,17s,18s)-11-ethyl-9-hydroperoxy-4,6,16,18-tetramethoxy-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-8,13-diol
n-(2-{4-[(2s)-2-[(2s,5s)-5-[2-(acetyloxy)propan-2-yl]-2-methyloxolan-2-yl]-2-hydroxyethoxy]phenyl}ethyl)benzenecarboximidic acid
C27H35NO6 (469.24642500000004)
(3s,3ar,4s,5r,6s,6ar,10s,12r,15r,15ar)-3-benzyl-4,5,10,12-tetramethyl-3h,3ah,4h,6h,6ah,9h,10h,11h,15h-cycloundeca[d]isoindole-1,5,6,12,15-pentol
9,19,26-trimethyl-1-azacyclohexacosa-1,3,5,7,15,17,19,21,23-nonaene-2,10,11,12,14-pentol
4-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-1-oxacyclododec-9-ene-2,8-dione
C25H43NO7 (469.30393680000003)