Exact Mass: 468.0886508

Exact Mass Matches: 468.0886508

Found 1 metabolites which its exact mass value is equals to given mass value 468.0886508, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Ulixertinib (hydrochloride)

Ulixertinib (hydrochloride)

C21H23Cl3N4O2 (468.0886508)


Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2].