Exact Mass: 458.22237400000006
Exact Mass Matches: 458.22237400000006
Found 162 metabolites which its exact mass value is equals to given mass value 458.22237400000006,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
fumagillin
A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01A - Agents against amoebiasis and other protozoal diseases C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D006133 - Growth Substances > D043924 - Angiogenesis Modulating Agents D000970 - Antineoplastic Agents > D020533 - Angiogenesis Inhibitors D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D006133 - Growth Substances > D006131 - Growth Inhibitors Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
Cinobufotalin
Cinobufotalin is a natural product found in Bufo and Bufo bufo with data available. Cinobufotalin is a bufadienolide isolated from toad venom and utilized in traditional Chinese medicine (TCM) for its cardiotonic, diuretic and hemostatic effects, with potential cytotoxic and antineoplastic activities. Upon administration and although the exact mechanism of action(s) (MoAs) through which this agent exerts its effects have yet to be fully discovered, cinobufotalin causes DNA fragmentation, decreases mitochondrial membrane potential (MMP), increases intracellular calcium (Ca2+) ion concentrations and reactive oxygen species (ROS) production, upregulates Fas protein and activates cytochrome C, various caspases, Bid and Bax. This causes cell cycle arrest, induces apoptosis and inhibits tumor cell growth and survival. In addition, cinobufotalin inhibits the activity of sphingosine kinase 1 (SphK1) and induces pro-apoptotic ceramide production, which further promotes tumor cell apoptosis. Cinobufotalin also induces mitochondrial protein cyclophilin D (Cyp-D)-dependent opening of the mitochondrial permeability transition pore (mPTP), which may contribute to cinobufotalin-induced non-apoptotic death of certain tumor cells. D020011 - Protective Agents > D002316 - Cardiotonic Agents > D002301 - Cardiac Glycosides D020011 - Protective Agents > D002316 - Cardiotonic Agents > D002018 - Bufanolides Cinobufotalin is a cardiotonic steroids or bufadienolides, is extracted from the skin secretions of the giant toads. Cinobufotalin has been used as a cardiotonic, diuretic and a hemostatic agent, Cinobufotalin is also a potential anti-lung cancer agent[1].
Hydroxystrobilurin D
Hydroxystrobilurin D is found in mushrooms. Hydroxystrobilurin D is isolated from Mycena sanguinolenta (blood mycena Isolated from Mycena sanguinolenta (blood mycena). Hydroxystrobilurin D is found in mushrooms.
fumagillin
2-Hydroxy-3-[(2-carboxyethyl)thio]-3-[2-(8-phenyloctyl)phenyl]propanoic acid
C26H34O5S (458.21268340000006)
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D020024 - Leukotriene Antagonists D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists
Cinobufotalin
Cinobufotalin is a cardiotonic steroids or bufadienolides, is extracted from the skin secretions of the giant toads. Cinobufotalin has been used as a cardiotonic, diuretic and a hemostatic agent, Cinobufotalin is also a potential anti-lung cancer agent[1].
(E)-8-(2-(4-(Diphenylamino)benzylidene)hydrazinyl)-N-hydroxy-8-oxooctanamide
C27H30N4O3 (458.23177899999996)
2-methyl-5-(1-methylethyl)-phenyl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside|carvacrol 2-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside
3alpha,11alpha-cyclotaxinine NN-2|3alpha,9alpha,10beta-triacetoxy-3alpha,11alpha-cyclotaxa-4(20),5-dien-13-one
6beta,9beta-diacetoxy-1alpha-benzoyloxydihydro-beta-agarofuran
4,6-decadiyne-1-O-alpha-L-rhamnopyranosyl-(1->6)-beta-D-glucopyranoside
berkeleyone B
A meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1.
berkeleyone C
A meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1.
Hydroxystrobilurin D
9-acetoxy-gamma-geraniol-(2,6-diacetyl-beta-D-glucopyranoside)
1alpha,8beta-diacetoxy-9beta-benzoyloxydihydro-beta-agarofuran
23-Methylauricepyron|23-Methylauricepyrone|Methylauricepyron
1alpha,15-diacetoxy-9beta-benzoyloxy-beta-dihydrofuran
C26H34O7_1,1,5a,7a,9,11b-Hexamethyl-7-methylene-3,8,11-trioxo-3,5a,5b,6,7,7a,8,9,11,11a,11b,12,13,13a-tetradecahydro-1H-isochromeno[7,8-g][2]benzoxepin-12-yl acetate
C26H34O7_8,12-Methanocycloocta[3,4]benz[1,2-c]oxepin-8(5H)-carboxylic acid, 3,5a,6,7,7a,9,10,11,12,13,13a,13b-dodecahydro-10-hydroxy-5,5,7a,10,12,13b-hexamethyl-14-methylene-3,9,11-trioxo-, methyl ester
2,7,7,11,15,17-hexamethyl-18-methylidene-5,13,16-trioxo-6,14-dioxatetracyclo[9.8.0.0²,⁸.0¹²,¹⁷]nonadec-3-en-10-yl acetate
2,7,7,11,15,17-hexamethyl-18-methylidene-5,13,16-trioxo-6,14-dioxatetracyclo[9.8.0.0²,⁸.0¹²,¹⁷]nonadec-3-en-10-yl acetate_major
2,7,7,11,15,17-hexamethyl-18-methylidene-5,13,16-trioxo-6,14-dioxatetracyclo[9.8.0.0²,?.0¹²,¹?]nonadec-3-en-10-yl acetate
Phe Gly His Val
Phe Gly Val His
Phe His Gly Val
Phe His Val Gly
Phe Val Gly His
Phe Val His Gly
Gly Phe His Val
Gly Phe Val His
Gly His Phe Val
Gly His Val Phe
Gly Val Phe His
Gly Val His Phe
His Phe Gly Val
His Phe Val Gly
His Gly Phe Val
His Gly Val Phe
His Thr Thr Thr
His Val Phe Gly
His Val Gly Phe
Asn Pro Gln Thr
Asn Pro Thr Gln
Asn Gln Pro Thr
Asn Gln Thr Pro
Asn Thr Pro Gln
Asn Thr Gln Pro
Pro Asn Gln Thr
Pro Asn Thr Gln
Pro Gln Asn Thr
Pro Gln Gln Ser
Pro Gln Ser Gln
Pro Gln Thr Asn
Pro Ser Gln Gln
Pro Thr Asn Gln
Pro Thr Gln Asn
Gln Asn Pro Thr
Gln Asn Thr Pro
Gln Pro Asn Thr
Gln Pro Gln Ser
Gln Pro Ser Gln
Gln Pro Thr Asn
Gln Gln Pro Ser
Gln Gln Ser Pro
Gln Ser Pro Gln
Gln Ser Gln Pro
Gln Thr Asn Pro
Gln Thr Pro Asn
Ser Pro Gln Gln
Ser Gln Pro Gln
Ser Gln Gln Pro
Thr His Thr Thr
Thr Asn Pro Gln
Thr Asn Gln Pro
Thr Pro Asn Gln
Thr Pro Gln Asn
Thr Gln Asn Pro
Thr Gln Pro Asn
Thr Thr His Thr
Thr Thr Thr His
Val Phe Gly His
Val Phe His Gly
Val Gly Phe His
Val Gly His Phe
Val His Phe Gly
Val His Gly Phe
17-trifluoromethylphenyl-13,14-dihydro trinor PGF2&alpha
C24H33F3O5 (458.22799640000005)
decanedioic acid,dimethyl benzene-1,4-dicarboxylate,ethane-1,2-diol
5-[(1R)-1-Hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-8-(phenylmethoxy)-2(1H)-quinolinone
4-(8-((4-((1S,4S)-5-Isopropyl-2,5-diazabicyclo(2.2.1)heptan-2-yl)phenyl)amino)-(1,2,4)triazolo(1,5-a)pyrazin-5-yl)furan-2-carboxamide
N-hydroxy-N-[(E)-[4-(N-phenylanilino)phenyl]methylideneamino]octanediamide
C27H30N4O3 (458.23177899999996)
D004791 - Enzyme Inhibitors > D056572 - Histone Deacetylase Inhibitors D000970 - Antineoplastic Agents
3-[(3-Aminomethyl-biphenyl-4-carbonyl)-amino]-2-(3-carbamimidoyl-benzyl)-butyric acid methyl ester
C27H30N4O3 (458.23177899999996)
4-(4-Hydroxy-2-methoxy-6-pentylbenzoyl)oxy-2-methoxy-6-pentylbenzoic acid
2-amino-N-[5-[(6-dimethylamino-9H-purin-9-yl)]-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]-3-(4-hydroxyphenyl)-propanamid
C21H28N7O5+ (458.21518180000004)
Fumagilina
Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
Berkeleytrione
A meroterpenoid found in Penicillium rubrum and has been shown to exhibit inhibitory activity against caspase-1.
O-demethylpuromycin(1+)
C21H28N7O5+ (458.21518180000004)
The conjugate acid of O-demethylpuromycin; major species at pH 7.3.
N-[[(2R,4S,5R)-5-[2-methyl-6-[4-(triluoromethyl)phenyl]pyrimidin-4-yl]-1-azabicyclo[2.2.2]octan-2-yl]methyl]cyclobutanecarboxamide
(6R,7S,8S)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7S,8S)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7R,8S)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7R,8R)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7R,8R)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6S,7S,8R)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7R,8S)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
(6R,7S,8R)-8-(hydroxymethyl)-4-[4-oxanyl(oxo)methyl]-7-[4-(3-phenylprop-1-ynyl)phenyl]-1,4-diazabicyclo[4.2.0]octan-2-one
L-alanyl-L-phenylalanyl-L-proline 2-naphthylamide
C27H30N4O3 (458.23177899999996)
6-hydroxy-6-(hydroxymethyl)-1,1,4a-trimethyl-5-{[(2-oxo-2H-chromen-7-yl)oxy]methyl}-decahydronaphthalen-2-yl acetate
6,8a-dihydroxy-1,1,4a,6-tetramethyl-5-{[(2-oxo-2H-chromen-7-yl)oxy]methyl}-decahydronaphthalen-2-yl acetate
6,7-dihydroxy-1,1,4a,6-tetramethyl-5-{[(2-oxo-2H-chromen-7-yl)oxy]methyl}-decahydronaphthalen-2-yl acetate
CID 14203
Cinobufotalin is a cardiotonic steroids or bufadienolides, is extracted from the skin secretions of the giant toads. Cinobufotalin has been used as a cardiotonic, diuretic and a hemostatic agent, Cinobufotalin is also a potential anti-lung cancer agent[1].
methyl (2Z,3E,5Z)-6-[4,4-dimethyl-3-(3-methylbut-2-enoxy)-2,3-dihydro-1,5-benzodioxepin-7-yl]-3-(hydroxymethyl)-2-(methoxymethylidene)hexa-3,5-dienoate
(1r,2r,4s,7s,8s,11r,12r,13r,16r)-7-(furan-3-yl)-13-(methoxymethyl)-1,8,12,15,15-pentamethyl-3,6,14-trioxapentacyclo[9.7.0.0²,⁴.0²,⁸.0¹²,¹⁶]octadecane-5,18-dione
3-{[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-en-1-yl)-5-(2-methylbutanoyl)phenyl]methyl}-6-ethyl-4-hydroxy-5-methylpyran-2-one
(1s,2r,5s,6s,7s,9r,12r)-7,12-bis(acetyloxy)-2,6,10,10-tetramethyl-11-oxatricyclo[7.2.1.0¹,⁶]dodecan-5-yl benzoate
methyl (2e,3z,5e)-6-(3-{[(2r)-3,3-dimethyloxiran-2-yl]methoxy}-4,4-dimethyl-2,3-dihydro-1,5-benzodioxepin-7-yl)-2-(methoxymethylidene)-3-methylhexa-3,5-dienoate
(2z,6e)-2-[(3r)-3-chloro-4-methylpent-4-en-1-yl]-9-[(2r)-6-hydroxy-2,8-dimethylchromen-2-yl]-6-methylnona-2,6-dienoic acid
C27H35ClO4 (458.22237400000006)