Exact Mass: 457.286

Exact Mass Matches: 457.286

Found 3 metabolites which its exact mass value is equals to given mass value 457.286, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Nevanimibe hydrochloride

Nevanimibe hydrochloride

C27H40ClN3O (457.286)


C471 - Enzyme Inhibitor Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1].

   

(4E,8E,12E)-2-(decanoylamino)-3-hydroxytetradeca-4,8,12-triene-1-sulfonic acid

(4E,8E,12E)-2-(decanoylamino)-3-hydroxytetradeca-4,8,12-triene-1-sulfonic acid

C24H43NO5S (457.2862)