Exact Mass: 456.9957

Exact Mass Matches: 456.9957

Found 1 metabolites which its exact mass value is equals to given mass value 456.9957, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

MB710

MB710

C16H16IN3O3S (456.9957)


MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C, with a Kd of 4.1?μM. MB710 shows anticancer activity in p53-Y220C cell lines[1].