Exact Mass: 454.1681

Exact Mass Matches: 454.1681

Found 1 metabolites which its exact mass value is equals to given mass value 454.1681, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

SIRT6 activator 12q

SIRT6 activator 12q

C31H22N2O2 (454.1681)


SIRT6 activator 12q is potent, selective and orally active SIRT6 activator with IC50 values of 171.20, >200, >200, >200, 0.58 μM for SIRT1, SIRT2, SIRT3, SIRT5, SIRT6, respectively. SIRT6 activator 12q inhibits cell growth and migration. SIRT6 activator 12q induces Apoptosis and cell cycle arrest at G2 phase. SIRT6 activator 12q shows anticancer activity[1].