Exact Mass: 449.00757920000007
Exact Mass Matches: 449.00757920000007
Found 11 metabolites which its exact mass value is equals to given mass value 449.00757920000007,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
K-Ras(G12C) inhibitor 12
C15H17ClIN3O3 (449.00031520000005)
K-Ras(G12C) inhibitor 12 is a K-Ras(G12C) inhibitor. K-Ras(G12C) inhibitor 12 acts on H1792 cells with an EC50 of 0.32 μM.
2-[2-CHLORO-6-(2-PYRIDYLTHIO)-4-PYRIDYL]-4-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE
1-Ethyl ester Methyl-3-Methylimidazolium bis(trifluoromethylsulfonyl)imide
1-(4-Iodobenzoyl)-5-methoxy-2-methyl indole-3-acetic acid
Adenosine 5-phosphosulfate (sodium salt)
C10H13N5NaO10PS (449.0018448000001)
Kobe0065
C15H11ClF3N5O4S (449.0172352000001)
Kobe0065 is a novel and effective inhibitor of Ras-Raf interaction, competitively inhibiting the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46±13 μM.
MIPS521
C19H10ClF6NOS (449.00757920000007)
MIPS521 is a positive allosteric modulator of adenosine A1 receptor (A1AR). MIPS521 also has a lower A1R allosteric affinity (pKB=4.95; KB=11?μM). MIPS521 exhibits pain-relieving effects in vivo through modulation of the increased levels of endogenous adenosine[1][2].