MgADP (BioDeep_00000840753)
代谢物信息卡片
MgADP
化学式: C10H13MgN5O10P2 (448.99881580000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)(O)[O-])O)O)N.[Mg+2]
InChI: /q
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jin Huang, Xuewen Liang, Minrui Zhao, Yue Zhang, Ziyang Chen. Metabolomics and network pharmacology reveal the mechanism of antithrombotic effect of Asperosaponin VI.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2024 Apr; 173(?):116355. doi:
10.1016/j.biopha.2024.116355. [PMID: 38493592] - Andrzej M Woyda-Ploszczyca. Direct and indirect targets of carboxyatractyloside, including overlooked toxicity toward nucleoside diphosphate kinase (NDPK) and mitochondrial H+ leak.
Pharmaceutical biology.
2023 Dec; 61(1):372-390. doi:
10.1080/13880209.2023.2168704. [PMID: 36799406] - Mohammed M Jalal, Claire S Whyte, Fraser P Coxon, Nicola J Mutch. Atorvastatin-mediated inhibition of prenylation of Rab27b and Rap1a in platelets attenuates their prothrombotic capacity and modulates clot structure.
Platelets.
2023 Dec; 34(1):2206921. doi:
10.1080/09537104.2023.2206921. [PMID: 37139869] - Zhongsuzhi Chen, Meiying He, Yijie Zhou, Xi Chen, Hong Zhu, Bao Yang, Yueming Jiang, Hongxia Qu. Degradation of water-soluble polysaccharides in pulp of litchi during storage.
Food chemistry.
2023 Feb; 402(?):134289. doi:
10.1016/j.foodchem.2022.134289. [PMID: 36150360] - Dongsheng Yao, Heba Ahmed, Junqi Song. A Clickable NAD+ Analog-Based Assay of Poly(ADP-Ribosyl)ated Proteins.
Methods in molecular biology (Clifton, N.J.).
2023; 2609(?):147-155. doi:
10.1007/978-1-0716-2891-1_10. [PMID: 36515835] - Leszek A Kleczkowski, Abir U Igamberdiev. Magnesium and cell energetics: At the junction of metabolism of adenylate and non-adenylate nucleotides.
Journal of plant physiology.
2023 Jan; 280(?):153901. doi:
10.1016/j.jplph.2022.153901. [PMID: 36549033] - Zahra Amri, Ikram Ben Amor, Amira Zarrouk, Raja Chaaba, Jalel Gargouri, Mohamed Hammami, Sonia Hammami. Anti-glycation, antiplatelet and antioxidant effects of different pomegranate parts.
BMC complementary medicine and therapies.
2022 Dec; 22(1):339. doi:
10.1186/s12906-022-03824-6. [PMID: 36575459] - Viacheslav V Dolgikh, Igor V Senderskiy, Sergej A Timofeev, Vladimir S Zhuravlyov, Alexandra V Dolgikh, Elena V Seliverstova, Diloram A Ismatullaeva, Bakhtiyar A Mirzakhodjaev. Construction of scFv Antibodies against the Outer Loops of the Microsporidium Nosema bombycis ATP/ADP-Transporters and Selection of the Fragment Efficiently Inhibiting Parasite Growth.
International journal of molecular sciences.
2022 Dec; 23(23):. doi:
10.3390/ijms232315307. [PMID: 36499634] - Jixing Lyu, Chang Liu, Tianqi Zhang, Samantha Schrecke, Nicklaus P Elam, Charles Packianathan, Georg K A Hochberg, David Russell, Minglei Zhao, Arthur Laganowsky. Structural basis for lipid and copper regulation of the ABC transporter MsbA.
Nature communications.
2022 11; 13(1):7291. doi:
10.1038/s41467-022-34905-2. [PMID: 36435815] - Pan Wang, Xingrong Peng, Tao Hou, Fangfang Xu, Han Zhou, Yancheng Yu, Minghua Qiu, Yanfang Liu, Yaopeng Zhao, Zhimou Guo, Jixia Wang, Xinmiao Liang. Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay.
Chemico-biological interactions.
2022 Nov; 367(?):110199. doi:
10.1016/j.cbi.2022.110199. [PMID: 36174740] - Zhang Yong, Wang Ruiqi, Yang Yanan, Ma Ning, Zhou Zhi, Tan Yinfeng, Dong Lin, Li Yiying, Lu Weiying, Wu Chongming, Zhang Xiaopo. Laurolitsine ameliorates type 2 diabetes by regulating the hepatic LKB1-AMPK pathway and gut microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Nov; 106(?):154423. doi:
10.1016/j.phymed.2022.154423. [PMID: 36075181] - Ping-An Yao, Ke-Zhao Wei, Jia-Hua Feng, Xiao-Ning Liu, Xu Xu, Hong-Yan Cui, Xiao-Chen Zhang, Jian-Ping Gao. Sodium houttuyfonate protects against cardiac injury by regulating cardiac energy metabolism in diabetic rats.
European journal of pharmacology.
2022 Oct; 932(?):175236. doi:
10.1016/j.ejphar.2022.175236. [PMID: 36044971] - Daniel Mouzo, Raquel Rodríguez-Vázquez, Carlos Barrio, Lucio García, Carlos Zapata. Comparative Proteomics of Potato Cultivars with a Variable Dormancy Period.
Molecules (Basel, Switzerland).
2022 Oct; 27(19):. doi:
10.3390/molecules27196621. [PMID: 36235158] - Jun Gyou Park, Songwon Kim, Eunhong Jang, Seung Hun Choi, Hyunsu Han, Seulgi Ju, Ji Won Kim, Da Sol Min, Mi Sun Jin. The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase.
Nature communications.
2022 10; 13(1):5851. doi:
10.1038/s41467-022-33593-2. [PMID: 36195619] - Xiao Chang, Yanhong He, Ling Wang, Chuanjin Luo, Yuntao Liu, Rong Li. Puerarin Alleviates LPS-Induced H9C2 Cell Injury by Inducing Mitochondrial Autophagy.
Journal of cardiovascular pharmacology.
2022 10; 80(4):600-608. doi:
10.1097/fjc.0000000000001315. [PMID: 35881898] - Archana Yadav, Chetna Singh. Cyclooxygenase-2 activates the free radical-mediated apoptosis of polymorphonuclear leukocytes in the maneb- and paraquat-intoxicated rats.
Pesticide biochemistry and physiology.
2022 Oct; 187(?):105202. doi:
10.1016/j.pestbp.2022.105202. [PMID: 36127053] - Iehor A Hudz, Volodymyr O Chernyshenko, Ludmila O Kasatkina, Lesia P Urvant, Vitaliy M Klimashevskyi, Oksana S Tkachenko, Halyna V Kosiakova, Nadiia M Hula, Tetyana M Platonova. N-Stearoylethanolamine Inhibits Integrin-Mediated Activation, Aggregation, and Adhesion of Human Platelets.
The Journal of pharmacology and experimental therapeutics.
2022 Oct; 383(1):2-10. doi:
10.1124/jpet.122.001084. [PMID: 35963618] - Sangsang Tang, Yuanming Shen, Xinyi Wei, Zhangjin Shen, Weiguo Lu, Junfen Xu. Olaparib synergizes with arsenic trioxide by promoting apoptosis and ferroptosis in platinum-resistant ovarian cancer.
Cell death & disease.
2022 09; 13(9):826. doi:
10.1038/s41419-022-05257-y. [PMID: 36163324] - Maryna Stasevych, Viktor Zvarych, Olena Yaremkevych, Mykhaylo Vovk, Alla Vaskevych, Tetiana Halenova, Olexii Savchuk. N-(9,10-Dioxo-9,10-dihydroanthracen-1(2)-yl)-2-(R-thio) Acetamides: Synthesis, Antioxidant and Antiplatelet Activity.
Acta chimica Slovenica.
2022 Sep; 69(3):584-595. doi:
10.17344/acsi.2022.7463. [PMID: 36196813] - Lyanne Rodríguez, Andrés Trostchansky, Hermine Vogel, Irene Wood, Iván Palomo, Sergio Wehinger, Eduardo Fuentes. A Comprehensive Literature Review on Cardioprotective Effects of Bioactive Compounds Present in Fruits of Aristotelia chilensis Stuntz (Maqui).
Molecules (Basel, Switzerland).
2022 Sep; 27(19):. doi:
10.3390/molecules27196147. [PMID: 36234679] - Nikolaos Fragakis, Antonios P Antoniadis, Melani Sotiriadou, Christina Virgiliou, Iris Ballauri, Helen G Gika, Dimitrios Bougiouklis, Spyros Gerou, Charalampos Lazaridis, Stavros Vergopoulos, Constantinos Bakogiannis, Georgios Giannopoulos, Georgios A Theodoridis, Christodoulos E Papadopoulos, Theodoros D Karamitsos, Vassilios Vassilikos. Syncope without prodromes is associated with excessive plasma release of adenosine at the time of syncope during head-up tilt table test.
International journal of cardiology.
2022 Sep; 363(?):43-48. doi:
10.1016/j.ijcard.2022.06.045. [PMID: 35716941] - Phong T Nguyen, Christine Deisl, Michael Fine, Trevor S Tippetts, Emiko Uchikawa, Xiao-Chen Bai, Beth Levine. Structural basis for gating mechanism of the human sodium-potassium pump.
Nature communications.
2022 09; 13(1):5293. doi:
10.1038/s41467-022-32990-x. [PMID: 36075933] - Robert Wolf, Sophie Grammbauer, Raghavendra Palankar, Céline Tolksdorf, Eileen Moritz, Andreas Böhm, Mahmoud Hasan, Annika Hafkemeyer, Andreas Greinacher, Mladen V Tzvetkov, Bernhard H Rauch, Gabriele Jedlitschky. Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets.
Haematologica.
2022 09; 107(9):2206-2217. doi:
10.3324/haematol.2021.279761. [PMID: 35295075] - Zalina I Iskhakova, Darya E Zhuravleva, Christopher Heim, Marcus D Hartmann, Aleksandr V Laykov, Karl Forchhammer, Airat R Kayumov. PotN represents a novel energy-state sensing PII subfamily, occurring in firmicutes.
The FEBS journal.
2022 09; 289(17):5305-5321. doi:
10.1111/febs.16431. [PMID: 35285159] - Piyas Gargari, Pradip Mukhopadhyay, Banshi Saboo, Anoop Misra, Sujoy Ghosh. Fabkin and glucose homeostasis.
Diabetes & metabolic syndrome.
2022 Aug; 16(8):102565. doi:
10.1016/j.dsx.2022.102565. [PMID: 35850074] - Douglas Jardim-Messeder, Márcia Margis-Pinheiro, Gilberto Sachetto-Martins. Salicylic acid and adenine nucleotides regulate the electron transport system and ROS production in plant mitochondria.
Biochimica et biophysica acta. Bioenergetics.
2022 08; 1863(6):148559. doi:
10.1016/j.bbabio.2022.148559. [PMID: 35413247] - Aolin Jia, Shijia Huang, Wen Song, Junli Wang, Yonggang Meng, Yue Sun, Lina Xu, Henriette Laessle, Jan Jirschitzka, Jiao Hou, Tiantian Zhang, Wenquan Yu, Giuliana Hessler, Ertong Li, Shoucai Ma, Dongli Yu, Jan Gebauer, Ulrich Baumann, Xiaohui Liu, Zhifu Han, Junbiao Chang, Jane E Parker, Jijie Chai. TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity.
Science (New York, N.Y.).
2022 07; 377(6605):eabq8180. doi:
10.1126/science.abq8180. [PMID: 35857644] - Shijia Huang, Aolin Jia, Wen Song, Giuliana Hessler, Yonggang Meng, Yue Sun, Lina Xu, Henriette Laessle, Jan Jirschitzka, Shoucai Ma, Yu Xiao, Dongli Yu, Jiao Hou, Ruiqi Liu, Huanhuan Sun, Xiaohui Liu, Zhifu Han, Junbiao Chang, Jane E Parker, Jijie Chai. Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity.
Science (New York, N.Y.).
2022 07; 377(6605):eabq3297. doi:
10.1126/science.abq3297. [PMID: 35857645] - Yue Hong, Hui Xia, Xiao Li, Ruyi Fan, Qing Li, Zhewen Ouyang, Shan Tang, Liang Guo. Brassica napus BnaNTT1 modulates ATP homeostasis in plastids to sustain metabolism and growth.
Cell reports.
2022 07; 40(2):111060. doi:
10.1016/j.celrep.2022.111060. [PMID: 35830794] - Shaojie Yang, Yan Qu, Juan Wang, Feng Gao, Manman Ji, Pan Xie, Aisong Zhu, Bei Tan, Xuncui Wang, Guoqi Zhu. Anshen Dingzhi prescription in the treatment of PTSD in mice: Investigation of the underlying mechanism from the perspective of hippocampal synaptic function.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2022 Jul; 101(?):154139. doi:
10.1016/j.phymed.2022.154139. [PMID: 35523115] - Guilherme Ruiz Leonardi, Caroline Honaiser Lescano, Jose Luiz Costa, Bruna Mazetto, Fernanda Andrade Orsi, Fabiola Zakia Monica. Adenosine diphosphate-induced aggregation is enhanced in platelets obtained from patients with thrombotic primary antiphospholipid syndrome (t-PAPS): Role of P2Y12 -cAMP signaling pathway.
Journal of thrombosis and haemostasis : JTH.
2022 07; 20(7):1699-1711. doi:
10.1111/jth.15724. [PMID: 35395698] - Yicong Bian, Jian Meng, Sheng Ma, Guangze Li, Yuya Wang, Shaorong Li, Linsheng Liu, Chenrong Huang, Hua Zhang, Dafang Zhong, Liyan Miao. Metabolite profiles and mass balance of fuzuloparib, a novel poly (ADP-ribose) polymerase inhibitor, in subjects with advanced solid cancers.
British journal of clinical pharmacology.
2022 07; 88(7):3307-3320. doi:
10.1111/bcp.15256. [PMID: 35112382] - Anja Eckelt, Franziska Wichmann, Franziska Bayer, John Eckelt, Jonathan Groß, Till Opatz, Kerstin Jurk, Christoph Reinhardt, Klytaimnistra Kiouptsi. Ethyl Hydroxyethyl Cellulose-A Biocompatible Polymer Carrier in Blood.
International journal of molecular sciences.
2022 Jun; 23(12):. doi:
10.3390/ijms23126432. [PMID: 35742876] - Edward Valera-Vera, Chantal Reigada, Melisa Sayé, Fabio A Digirolamo, Facundo Galceran, Mariana R Miranda, Claudio A Pereira. Trypanocidal activity of the anthocyanidin delphinidin, a non-competitive inhibitor of arginine kinase.
Natural product research.
2022 Jun; 36(12):3153-3157. doi:
10.1080/14786419.2021.1947270. [PMID: 34219561] - Natália Pontes Bona, Mayara Sandrielly Pereira Soares, Nathalia Stark Pedra, Luiza Spohr, Francieli da Silva Dos Santos, Alana Seixas de Farias, Fernando Lopez Alvez, Bernardo de Moraes Meine, Karina Pereira Luduvico, Roselia Maria Spanevello, Francieli Moro Stefanello. Tannic Acid Attenuates Peripheral and Brain Changes in a Preclinical Rat Model of Glioblastoma by Modulating Oxidative Stress and Purinergic Signaling.
Neurochemical research.
2022 Jun; 47(6):1541-1552. doi:
10.1007/s11064-022-03547-7. [PMID: 35178643] - Qiuzi Yi, Shihao Yao, Boyuan Ma, Xiaohui Cang. The effects of cardiolipin on the structural dynamics of the mitochondrial ADP/ATP carrier in its cytosol-open state.
Journal of lipid research.
2022 06; 63(6):100227. doi:
10.1016/j.jlr.2022.100227. [PMID: 35569528] - Carola Ledderose, Eleftheria-Angeliki Valsami, Wolfgang G Junger. Optimized HPLC method to elucidate the complex purinergic signaling dynamics that regulate ATP, ADP, AMP, and adenosine levels in human blood.
Purinergic signalling.
2022 06; 18(2):223-239. doi:
10.1007/s11302-022-09842-w. [PMID: 35132577] - Bongsoo Choi, Do Young Hyeon, Juhun Lee, Terri A Long, Daehee Hwang, Inhwan Hwang. E3 ligase BRUTUS Is a Negative Regulator for the Cellular Energy Level and the Expression of Energy Metabolism-Related Genes Encoded by Two Organellar Genomes in Leaf Tissues.
Molecules and cells.
2022 May; 45(5):294-305. doi:
10.14348/molcells.2022.2029. [PMID: 35422451] - Tianyun Fan, Yangyang Cheng, Wei Wei, Qingxuan Zeng, Xixi Guo, Zhihao Guo, Yinghong Li, Liping Zhao, Yulong Shi, Xintong Zhang, Jiandong Jiang, Yanxiang Wang, Weijia Kong, Danqing Song. Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3-Kinase/Akt Phosphorylation.
Journal of medicinal chemistry.
2022 05; 65(10):7399-7413. doi:
10.1021/acs.jmedchem.2c00592. [PMID: 35549263] - Marta Zarà, Mauro Vismara, Gianluca De Dona, Silvia M G Trivigno, Patrizia Amadio, Leonardo Sandrini, Gianni F Guidetti, Silvia S Barbieri. The Impact of Platelet Isolation Protocol on the Release of Extracellular Vesicles.
Frontiers in bioscience (Landmark edition).
2022 05; 27(5):161. doi:
10.31083/j.fbl2705161. [PMID: 35638428] - Ceren Eyileten, Aleksandra Gasecka, Anna Nowak, Joanna Jarosz-Popek, Marta Wolska, Al-Medina Dizdarevic, Irene M Lang, Marek Postula, Marcin Ufnal, Jolanta M Siller-Matula. High concentration of symmetric dimethylarginine is associated with low platelet reactivity and increased bleeding risk in patients with acute coronary syndrome.
Thrombosis research.
2022 05; 213(?):195-202. doi:
10.1016/j.thromres.2022.03.025. [PMID: 35398728] - Andrea Pagano, Lorena Zannino, Paola Pagano, Enrico Doria, Daniele Dondi, Anca Macovei, Marco Biggiogera, Susana de Sousa Araújo, Alma Balestrazzi. Changes in genotoxic stress response, ribogenesis and PAP (3'-phosphoadenosine 5'-phosphate) levels are associated with loss of desiccation tolerance in overprimed Medicago truncatula seeds.
Plant, cell & environment.
2022 05; 45(5):1457-1473. doi:
10.1111/pce.14295. [PMID: 35188276] - Johanna C Clauser, Judith Maas, Ilona Mager, Frank R Halfwerk, Jutta Arens. The porcine abattoir blood model-Evaluation of platelet function for in-vitro hemocompatibility investigations.
Artificial organs.
2022 May; 46(5):922-931. doi:
10.1111/aor.14146. [PMID: 34904246] - Luba Marderfeld, Orith Waisbourd-Zinman, Neta Biran, Michal Rozenfeld Bar-Lev, Ari Silbermintz, Irit Poraz, Dana Reznik, Yifat Jack, Yael Mozer Glassberg, Raanan Shamir. Body composition correlates with laboratory parameters and disease severity in infants with biliary atresia.
Pediatric transplantation.
2022 05; 26(3):e14208. doi:
10.1111/petr.14208. [PMID: 34927330] - Dominique-Maurice Kehlenbeck, Daouda A K Traore, Inokentijs Josts, Simon Sander, Martine Moulin, Michael Haertlein, Sylvain Prevost, V Trevor Forsyth, Henning Tidow. Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination.
The FEBS journal.
2022 05; 289(10):2959-2970. doi:
10.1111/febs.16327. [PMID: 34921499] - Mahmoud F Kamel, Mahmoud Nassar, Amira Elbendary, Abdelrahman Gamal Abdelaziz Mohamed, Mahmoud Gouda Abdullah, Hassan Ramdan Abdelazeem Gomaa, Ebram Medhat Ibrahim Awad, Heba H Mahmoud, Mohamed A Elfiki, Nilly H Abdalla, Rehab M Abd Elkareem, Ayman S Soliman, Riem M Elmessiery. The potential use of urinary transferrin, urinary adiponectin, urinary Retinol Binding Protein, and serum zinc alpha 2 glycoprotein levels as novel biomarkers for early diagnosis of diabetic nephropathy: A case-control study.
Diabetes & metabolic syndrome.
2022 Apr; 16(4):102473. doi:
10.1016/j.dsx.2022.102473. [PMID: 35405355] - Sandra C Bulla, Peres R Badial, Camilo Bulla. Canine Cancer Cells Activate Platelets via the Platelet P2Y12 Receptor.
Journal of comparative pathology.
2022 Apr; 192(?):41-49. doi:
10.1016/j.jcpa.2022.01.002. [PMID: 35305713] - Chengcheng Fan, Douglas C Rees. Glutathione binding to the plant AtAtm3 transporter and implications for the conformational coupling of ABC transporters.
eLife.
2022 03; 11(?):. doi:
10.7554/elife.76140. [PMID: 35333177] - Yan-Jun Lin, Kun-Li Jiao, Bo Liu, Lu Fang, Shu Meng. Antiplatelet and myocardial protective effect of Shexiang Tongxin Dropping Pill in patients undergoing percutaneous coronary intervention: A randomized controlled trial.
Journal of integrative medicine.
2022 03; 20(2):126-134. doi:
10.1016/j.joim.2022.01.001. [PMID: 35101369] - Mingyi Lv, Dengmei Xie, Xiaofeng Long. The effect of fenofibrate, a peroxisome proliferator-activated receptor α agonist, on cardiac damage from sepsis in BALB/c mice.
Cellular and molecular biology (Noisy-le-Grand, France).
2022 Feb; 67(6):260-266. doi:
10.14715/cmb/2021.67.6.34. [PMID: 35818188] - D-L Wang, X Li, R-N Wang, Y Sun, X-S Xia, W-J Tian, L Wang. A study of microRNA-223 in evaluating platelet reactivity in patients with acute ischemic stroke.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2022 Feb; 73(1):. doi:
10.26402/jpp.2022.1.11. [PMID: 35793763] - Abderrahim Nemmar, Marc F Hoylaerts. Neutrophil Cathepsin G Enhances Thrombogenicity of Mildly Injured Arteries via ADP-Mediated Platelet Sensitization.
International journal of molecular sciences.
2022 Jan; 23(2):. doi:
10.3390/ijms23020744. [PMID: 35054930] - Fabrice Lucien, Eduardo E Benarroch, Aidan Mullan, Farwa Ali, Bradley F Boeve, Michelle M Mielke, Ronald C Petersen, Yohan Kim, Cole Stang, Emanuele Camerucci, Owen A Ross, Zbigniew K Wszolek, David Knopman, James Bower, Wolfgang Singer, Rodolfo Savica. Poly (ADP-Ribose) and α-synuclein extracellular vesicles in patients with Parkinson disease: A possible biomarker of disease severity.
PloS one.
2022; 17(4):e0264446. doi:
10.1371/journal.pone.0264446. [PMID: 35395000] - Kai Jakobs, Leander Reinshagen, Marianna Puccini, Julian Friebel, Anne-Christin Beatrice Wilde, Ayman Alsheik, Andi Rroku, Ulf Landmesser, Arash Haghikia, Nicolle Kränkel, Ursula Rauch-Kröhnert. Disease Severity in Moderate-to-Severe COVID-19 Is Associated With Platelet Hyperreactivity and Innate Immune Activation.
Frontiers in immunology.
2022; 13(?):844701. doi:
10.3389/fimmu.2022.844701. [PMID: 35359931] - Elena Díaz-García, Sara García-Tovar, Enrique Alfaro, Ester Zamarrón, Alberto Mangas, Raúl Galera, José Juan Ruíz-Hernández, Jordi Solé-Violán, Carlos Rodríguez-Gallego, Ana Van-Den-Rym, Rebeca Pérez-de-Diego, Kapil Nanwani-Nanwani, Eduardo López-Collazo, Francisco García-Rio, Carolina Cubillos-Zapata. Role of CD39 in COVID-19 Severity: Dysregulation of Purinergic Signaling and Thromboinflammation.
Frontiers in immunology.
2022; 13(?):847894. doi:
10.3389/fimmu.2022.847894. [PMID: 35173744] - Natalia Rukoyatkina, Valentina Shpakova, Alina Bogoutdinova, Alexandra Kharazova, Igor Mindukshev, Stepan Gambaryan. Curcumin by activation of adenosine A2A receptor stimulates protein kinase a and potentiates inhibitory effect of cangrelor on platelets.
Biochemical and biophysical research communications.
2022 01; 586(?):20-26. doi:
10.1016/j.bbrc.2021.11.006. [PMID: 34823218] - Tatiana R Rosenstock, Congxin Sun, Georgina Wynne Hughes, Katherine Winter, Sovan Sarkar. Analysis of Mitochondrial Dysfunction by Microplate Reader in hiPSC-Derived Neuronal Cell Models of Neurodegenerative Disorders.
Methods in molecular biology (Clifton, N.J.).
2022; 2549(?):1-21. doi:
10.1007/7651_2021_451. [PMID: 35347693] - Fangfei Li, Xiaoqiu Wu, Xuekun Fu, Jin Liu, Wangze Song, Gary Guishan Xiao, Aiping Lu, Ge Zhang. Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation.
International journal of biological sciences.
2022; 18(3):1238-1253. doi:
10.7150/ijbs.58784. [PMID: 35173550] - Monica Hoang, Emelien Jentz, Sarah M Janssen, Daniela Nasteska, Federica Cuozzo, David J Hodson, A Russell Tupling, Guo-Hua Fong, Jamie W Joseph. Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
Endocrinology.
2022 01; 163(1):. doi:
10.1210/endocr/bqab226. [PMID: 34718519] - Devaraja Sannaningaiah, Ashwini Shivaiah, Jayanna Kengaiah, Chandramma Srinivasa, Sharath Kumar M Nandish, Chethana Ramachandraiah, Sujatha Hanumegowda, Bhagyalakshmi Manjappa, Sebastin Santosh Martin, Ramesh Komalapura Laxmaiah, Manohar Shinde. Sorghum Protein Extract Protects RBC from Sodium Nitrite-Induced Oxidative Stress and Exhibits Anticoagulant and Antiplatelet Activity.
Folia medica.
2021 Dec; 63(6):884-894. doi:
10.3897/folmed.63.e57713. [PMID: 35851225] - Yang Zhou, Chun Dai, Bing Zhang, Jianjun Ge. Adiponectin Prevents Restenosis Through Inhibiting Cell Proliferation in a Rat Vein Graft Model.
Arquivos brasileiros de cardiologia.
2021 12; 117(6):1179-1188. doi:
10.36660/abc.20200761. [PMID: 35613174] - Chen Zhao, Roderick MacKinnon. Molecular structure of an open human KATP channel.
Proceedings of the National Academy of Sciences of the United States of America.
2021 11; 118(48):. doi:
10.1073/pnas.2112267118. [PMID: 34815345] - Liang Kong, Baomin Feng, Yan Yan, Chao Zhang, Jun Hyeok Kim, Lahong Xu, Johannes Gregor Matthias Rack, Ying Wang, Jyan-Chyun Jang, Ivan Ahel, Libo Shan, Ping He. Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity.
Molecular cell.
2021 11; 81(22):4591-4604.e8. doi:
10.1016/j.molcel.2021.09.006. [PMID: 34592134] - Benjamin A Heitz, Robert Bränström, Wei Yang, Yiding Huang, Tilo Moede, Ingo B Leibiger, Barbara Leibiger, Liu Qi Chen, Jia Yu, Shao-Nian Yang, Olof Larsson, S Scott Saavedra, Per-Olof Berggren, Craig A Aspinwall. Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K+ channels.
Scientific reports.
2021 11; 11(1):21539. doi:
10.1038/s41598-021-00988-y. [PMID: 34728728] - Casey Whyte, Ting Fung Ma, Jeffrey Sindelar, Scott Rankin. Rapid Hygiene Assay Sensitive to Cumulative Adenylate Homologues Exhibits Equal or Higher Frequencies of Soil Contamination Detection than Assay Limited to ATP Detection.
Journal of food protection.
2021 11; 84(11):1937-1944. doi:
10.4315/jfp-21-028. [PMID: 34265064] - Chigusa Kobayashi, Yasuhiro Matsunaga, Jaewoon Jung, Yuji Sugita. Structural and energetic analysis of metastable intermediate states in the E1P-E2P transition of Ca2+-ATPase.
Proceedings of the National Academy of Sciences of the United States of America.
2021 10; 118(40):. doi:
10.1073/pnas.2105507118. [PMID: 34593638] - Yuuma Ishikawa, Cedric Cassan, Aikeranmu Kadeer, Koki Yuasa, Nozomu Sato, Kintake Sonoike, Yasuko Kaneko, Atsuko Miyagi, Hiroko Takahashi, Toshiki Ishikawa, Masatoshi Yamaguchi, Yoshitaka Nishiyama, Yukako Hihara, Yves Gibon, Maki Kawai-Yamada. The NAD Kinase Slr0400 Functions as a Growth Repressor in Synechocystis sp. PCC 6803.
Plant & cell physiology.
2021 Sep; 62(4):668-677. doi:
10.1093/pcp/pcab023. [PMID: 33560438] - Wayne Willis, Elizabeth Willis, Sarah Kuzmiak-Glancy, Katon Kras, Jamie Hudgens, Neusha Barakati, Jennifer Stern, Lawrence Mandarino. Oxidative phosphorylation K0.5ADP in vitro depends on substrate oxidative capacity: Insights from a luciferase-based assay to evaluate ADP kinetic parameters.
Biochimica et biophysica acta. Bioenergetics.
2021 08; 1862(8):148430. doi:
10.1016/j.bbabio.2021.148430. [PMID: 33887230] - Henver S Brunetta, Heather L Petrick, Bayley Vachon, Everson A Nunes, Graham P Holloway. Insulin rapidly increases skeletal muscle mitochondrial ADP sensitivity in the absence of a high lipid environment.
The Biochemical journal.
2021 07; 478(13):2539-2553. doi:
10.1042/bcj20210264. [PMID: 34129667] - Xiao Zuo, Qing Li, Fuli Ya, Li-Juan Ma, Zezhong Tian, Mingzhu Zhao, Die Fan, Yimin Zhao, Yu-Heng Mao, Jian-Bo Wan, Yan Yang. Ginsenosides Rb2 and Rd2 isolated from Panax notoginseng flowers attenuate platelet function through P2Y12-mediated cAMP/PKA and PI3K/Akt/Erk1/2 signaling.
Food & function.
2021 Jul; 12(13):5793-5805. doi:
10.1039/d1fo00531f. [PMID: 34041517] - A A Savchenko, A G Borisov, V D Belenyuk, A V Moshev. Changes in the Subpopulation Composition and Phagocytic Activity of Monocytes in Patients with Kidney Cancer under the Influence of Metabolites In Vitro.
Bulletin of experimental biology and medicine.
2021 Jul; 171(3):362-366. doi:
10.1007/s10517-021-05228-x. [PMID: 34297298] - Bérengère Papegay, Vincent Nuyens, Adelin Albert, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Oberdan Leo, Véronique Kruys, Jean G Boogaerts, Joseph Vamecq. Adenosine Diphosphate and the P2Y13 Receptor Are Involved in the Autophagic Protection of Ex Vivo Perfused Livers From Fasted Rats: Potential Benefit for Liver Graft Preservation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
2021 07; 27(7):997-1006. doi:
10.1002/lt.25970. [PMID: 33306256] - Changping Zhou, Huigang Shi, Manfeng Zhang, Lijun Zhou, Le Xiao, Shasha Feng, Wonpil Im, Min Zhou, Xinzheng Zhang, Yihua Huang. Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa.
Journal of molecular biology.
2021 06; 433(13):166986. doi:
10.1016/j.jmb.2021.166986. [PMID: 33845086] - Stephanie C Lüthi, Anna Howald, Kathrin Nowak, Robert Graage, Giody Bartolomei, Christine Neupert, Xaver Sidler, Deena Leslie Pedrioli, Michael O Hottiger. Establishment of a Mass-Spectrometry-Based Method for the Identification of the In Vivo Whole Blood and Plasma ADP-Ribosylomes.
Journal of proteome research.
2021 06; 20(6):3090-3101. doi:
10.1021/acs.jproteome.0c00923. [PMID: 34032442] - Pedro H Doleski, Fernanda L Cabral, Stephen A Adefegha, Matheus H Jantsch, Renan S Ebone, Daniela B R Leal, Maria R C Schetinger. Distinct kinetics for nucleotide hydrolysis in lymphocytes isolated from blood, spleen and cervical lymph nodes: Characterization of ectonucleotidase activity.
Cell biochemistry and function.
2021 Jun; 39(4):511-520. doi:
10.1002/cbf.3616. [PMID: 33783015] - Abir U Igamberdiev, Leszek A Kleczkowski. Pyrophosphate as an alternative energy currency in plants.
The Biochemical journal.
2021 04; 478(8):1515-1524. doi:
10.1042/bcj20200940. [PMID: 33881486] - Xiaoliang Liu, Ling Hu, Yuan Zhang, Hongtao Li. Expression of adenylate kinase fused mouse ubiquitin active enzyme in Escherichia coli and its application in ubiquitination.
Bioscience, biotechnology, and biochemistry.
2021 Apr; 85(5):1140-1146. doi:
10.1093/bbb/zbab026. [PMID: 33599725] - Ying Xue, Zi Wang, Hongyi Wu, Xiaoye Li, Jiahui Chen, Qianzhou Lv. Cilostazol increases adenosine plasma concentration in patients with acute coronary syndrome.
Journal of clinical pharmacy and therapeutics.
2021 Apr; 46(2):328-332. doi:
10.1111/jcpt.13284. [PMID: 33052628] - Asami Kamada, Mie Shimizu, Kazumasa Oura, Makiko Yoshida, Keisuke Tsuda, Kiyotaka Oi, Yoko Ishigaku, Tatsunori Natori, Shinsuke Narumi, Ryo Itabashi, Tetsuya Maeda, Yasuo Terayama. Inhibitory Effects of P2Y12 Receptor Antagonist on PAR1- and PAR4-AP-Induced Platelet Aggregation in Patients with Stroke or TIA.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.
2021 Mar; 30(3):105547. doi:
10.1016/j.jstrokecerebrovasdis.2020.105547. [PMID: 33360254] - Toshihiro Kishikawa, Yuichi Maeda, Takuro Nii, Noriko Arase, Jun Hirata, Ken Suzuki, Kenichi Yamamoto, Tatsuo Masuda, Kotaro Ogawa, Shigeyoshi Tsuji, Masato Matsushita, Hidetoshi Matsuoka, Maiko Yoshimura, Shinichiro Tsunoda, Shiro Ohshima, Masashi Narazaki, Atsushi Ogata, Yukihiko Saeki, Hidenori Inohara, Atsushi Kumanogoh, Kiyoshi Takeda, Yukinori Okada. Increased levels of plasma nucleotides in patients with rheumatoid arthritis.
International immunology.
2021 01; 33(2):119-124. doi:
10.1093/intimm/dxaa059. [PMID: 32866240] - Caroline Honaiser Lescano, Fernando Freitas de Lima, Claudia Andrea Lima Cardoso, Silvia Cristina Heredia Vieira, Fabíola Zakia Mónica, Ivan Pires de Oliveira. Rutin present in Alibertia edulis extract acts on human platelet aggregation through inhibition of cyclooxygenase/thromboxane.
Food & function.
2021 Jan; 12(2):802-814. doi:
10.1039/d0fo02276d. [PMID: 33393955] - Juan Carlos Gil-Redondo, Jagoba Iturri, Felipe Ortega, Raquel Pérez-Sen, Andreas Weber, María Teresa Miras-Portugal, José Luis Toca-Herrera, Esmerilda G Delicado. Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy.
International journal of molecular sciences.
2021 Jan; 22(2):. doi:
10.3390/ijms22020624. [PMID: 33435130] - Amirah Mohammad-Sidik, Jian Sun, Ryoung Shin, Zhizhong Song, Youzheng Ning, Elsa Matthus, Katie A Wilkins, Julia M Davies. Annexin 1 Is a Component of eATP-Induced Cytosolic Calcium Elevation in Arabidopsis thaliana Roots.
International journal of molecular sciences.
2021 Jan; 22(2):. doi:
10.3390/ijms22020494. [PMID: 33419052] - Harald Haidl, Johanna Gaugler, Gerhard Cvirn, Hildegard Jasser-Nitsche, Wolfgang Schwinger, Sina Pohl, Egbert Bisping, Siegfried Gallistl, Axel Schlagenhauf. Impact of electric cardioversion on platelet activation.
PloS one.
2021; 16(4):e0250353. doi:
10.1371/journal.pone.0250353. [PMID: 33886660] - Xue Peng, Zhang Yong, Wang Xiaoyan, Cui Yuanshan, Wei Guangzhu, Liu Xuehuan. Mechanism of Graft Damage Caused by NTPDase1-activated Macrophages in Acute Antibody-Mediated Rejection.
Transplantation proceedings.
2021 Jan; 53(1):436-442. doi:
10.1016/j.transproceed.2020.06.033. [PMID: 32773283] - Rajat Srivastava, Akash, Adwaita Prasad Parida, Pankaj Kumar Chauhan, Rahul Kumar. Identification, structure analysis, and transcript profiling of purple acid phosphatases under Pi deficiency in tomato (Solanum lycopersicum L.) and its wild relatives.
International journal of biological macromolecules.
2020 Dec; 165(Pt B):2253-2266. doi:
10.1016/j.ijbiomac.2020.10.080. [PMID: 33098900] - Jian Yang, Ke Li, Chunzhong Li, Jinlou Gu. Intrinsic Apyrase-Like Activity of Cerium-Based Metal-Organic Frameworks (MOFs): Dephosphorylation of Adenosine Tri- and Diphosphate.
Angewandte Chemie (International ed. in English).
2020 12; 59(51):22952-22956. doi:
10.1002/anie.202008259. [PMID: 32902900] - Theodore E Liston, Sonja Hinz, Christa E Müller, Deborah M Holstein, Jay Wendling, Roger J Melton, Mary Campbell, William S Korinek, R Rama Suresh, Dane A Sethre-Hofstad, Zhan-Guo Gao, Dilip K Tosh, Kenneth A Jacobson, James D Lechleiter. Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology.
Purinergic signalling.
2020 12; 16(4):543-559. doi:
10.1007/s11302-020-09732-z. [PMID: 33129204] - Yicong Ye, Xiliang Zhao, Chenchen Tu, Quan Li, Yong Zeng. Elevated Serum Levels of Alkaline Phosphatase and the Risk of Low Responsiveness to Clopidogrel.
International heart journal.
2020 Nov; 61(6):1135-1141. doi:
10.1536/ihj.20-285. [PMID: 33116024] - Cuiting Chen, Yiqing Meng, Jannat Shopan, James Whelan, Zhongyuan Hu, Jinghua Yang, Mingfang Zhang. Identification and characterization of Arabidopsis thaliana mitochondrial F1F0-ATPase inhibitor factor 1.
Journal of plant physiology.
2020 Nov; 254(?):153264. doi:
10.1016/j.jplph.2020.153264. [PMID: 33032063] - Alexander E Conicella, Rui Huang, Zev A Ripstein, Ai Nguyen, Eric Wang, Thomas Löhr, Peter Schuck, Michele Vendruscolo, John L Rubinstein, Lewis E Kay. An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase.
Proceedings of the National Academy of Sciences of the United States of America.
2020 10; 117(42):26226-26236. doi:
10.1073/pnas.2013920117. [PMID: 33028677] - Mei Chou Lai, Wayne Young Liu, Shorong-Shii Liou, I-Min Liu. A Bibenzyl Component Moscatilin Mitigates Glycation-Mediated Damages in an SH-SY5Y Cell Model of Neurodegenerative Diseases through AMPK Activation and RAGE/NF-κB Pathway Suppression.
Molecules (Basel, Switzerland).
2020 Oct; 25(19):. doi:
10.3390/molecules25194574. [PMID: 33036367] - Soumen Bera, Mubasher Rashid, Alexander B Medvinsky, Gui-Quan Sun, Bai-Lian Li, Claudia Acquisti, Adnan Sljoka, Amit Chakraborty. Allosteric regulation of glutamate dehydrogenase deamination activity.
Scientific reports.
2020 10; 10(1):16523. doi:
10.1038/s41598-020-73743-4. [PMID: 33020580] - Manting Huang, Huanlin Wu, Jianping Wu, Qiuxiong Chen, Dezhi Zou, Danping Xu. Prevention of platelet aggregation and arterial thrombosis using a modified Shenzhu Guanxin Formula.
The Journal of international medical research.
2020 Oct; 48(10):300060520941326. doi:
10.1177/0300060520941326. [PMID: 33086881] - Akari Miyazaki, Takeshi Uehara, Yoko Usami, Nau Ishimine, Mitsutoshi Sugano, Minoru Tozuka. Highly oxidized low-density lipoprotein does not facilitate platelet aggregation.
The Journal of international medical research.
2020 Oct; 48(10):300060520958960. doi:
10.1177/0300060520958960. [PMID: 33100088] - N N Drozd, S A Kuznetsova, Yu N Malyar, N Yu Vasilyeva, B N Kuznetsov. Study of the Blood Compatibility of Sulfated Organosolv Lignins Derived from Abies sibirica and Larix sibirica Wood Pulp.
Bulletin of experimental biology and medicine.
2020 Oct; 169(6):815-820. doi:
10.1007/s10517-020-04987-3. [PMID: 33123918] - Klytaimnistra Kiouptsi, Sven Jäckel, Eivor Wilms, Giulia Pontarollo, Jana Winterstein, Cornelia Karwot, Kathrin Groß, Kerstin Jurk, Christoph Reinhardt. The Commensal Microbiota Enhances ADP-Triggered Integrin αIIbβ3 Activation and von Willebrand Factor-Mediated Platelet Deposition to Type I Collagen.
International journal of molecular sciences.
2020 Sep; 21(19):. doi:
10.3390/ijms21197171. [PMID: 32998468] - James Chen, Brandon Malone, Eliza Llewellyn, Michael Grasso, Patrick M M Shelton, Paul Dominic B Olinares, Kashyap Maruthi, Edward T Eng, Hasan Vatandaslar, Brian T Chait, Tarun M Kapoor, Seth A Darst, Elizabeth A Campbell. Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
Cell.
2020 09; 182(6):1560-1573.e13. doi:
10.1016/j.cell.2020.07.033. [PMID: 32783916] - Xiangtang Li, Xun Liao, Yi-Ming Liu. A microfluidic platform integrating paper adsorption-based sample clean-up and voltage-assisted liquid desorption electrospray ionization mass spectrometry for biological sample analysis.
Talanta.
2020 Sep; 217(?):121106. doi:
10.1016/j.talanta.2020.121106. [PMID: 32498849]