Exact Mass: 447.14058360000007
Exact Mass Matches: 447.14058360000007
Found 1 metabolites which its exact mass value is equals to given mass value 447.14058360000007,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
Glucosylceramide synthase-IN-2
Glucosylceramide synthase-IN-2
C22H20F3N3O4 (447.14058360000007)
Glucosylceramide synthase-IN-2 (compound T-690) is a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC50s of 15 nM and 190 nM for human GCS and mouse GCS, respectively.Glucosylceramide synthase-IN-2 exhibits noncompetitive type inhibition with C8-ceramide and UDP-glucose.Glucosylceramide synthase-IN-2 can be used for Gaucher's disease research[1].