Exact Mass: 446.9365

Exact Mass Matches: 446.9365

Found 1 metabolites which its exact mass value is equals to given mass value 446.9365, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

BMS-986122

BMS-986122

C16H15BrClNO3S2 (446.9365)


BMS-986122 is a selective, potent positive allosteric modulator of the mu-opioid receptor (μ-OR). BMS-986122 shows potentiation of orthosteric agonist-mediated β-arrestin recruitment, adenylyl cyclase inhibition, and G protein activation. BMS-986122 potentiates DAMGO-mediated [35S]GTPγS binding in mouse brain membranes[1][2].