Exact Mass: 445.1899

Exact Mass Matches: 445.1899

Found 1 metabolites which its exact mass value is equals to given mass value 445.1899, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Samelisant

Samelisant

C21H33Cl2N3O3 (445.1899)


Samelisant (SUVN-G3031) is a potent and selective histamine H3 receptor (H3R) inverse agonist with good brain penetration and oral bioavailability. Samelisant has a similar binding affinity towards human (hH3R; Ki=8.7 nM) and rat (rH3R;Ki=9.8 nM) H3R indicating no inter-species differences. Samelisant can be used for the research of sleep-related disorders[1].