Exact Mass: 445.1899

Exact Mass Matches: 445.1899

Found 1 metabolites which its exact mass value is equals to given mass value 445.1899, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Samelisant

Samelisant

C21H33Cl2N3O3 (445.1899)


Samelisant (SUVN-G3031) is a potent and selective histamine H3 receptor (H3R) inverse agonist with good brain penetration and oral bioavailability. Samelisant has a similar binding affinity towards human (hH3R; Ki=8.7 nM) and rat (rH3R;Ki=9.8 nM) H3R indicating no inter-species differences. Samelisant can be used for the research of sleep-related disorders[1].