Exact Mass: 443.103

Exact Mass Matches: 443.103

Found 2 metabolites which its exact mass value is equals to given mass value 443.103, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

N-debutylhalofantrine

3-(butylamino)-1-[1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl]propan-1-ol

C22H22Cl2F3NO (443.103)


N-debutylhalofantrine is a metabolite of halofantrine. Halofantrine is a drug used to treat malaria. Halofantrines structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown. A crystallographic study have shown that halofantrine binds to hematin in vitro, suggesting a possible mechanism of action. (Wikipedia) D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents

   

Desmethylhalofantrine

1,3-dichloro-6-trifluoromethyl-9-phenanthryl-3-(n-butyl)aminopropanol

C22H22Cl2F3NO (443.103)