Exact Mass: 431.166739

Exact Mass Matches: 431.166739

Found 2 metabolites which its exact mass value is equals to given mass value 431.166739, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

   

NVP 231

NVP 231

C25H25N3O2S (431.166739)


NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK[1]. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage[2].