Exact Mass: 427.25364740000003

Exact Mass Matches: 427.25364740000003

Found 58 metabolites which its exact mass value is equals to given mass value 427.25364740000003, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Ranolazine

N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide

C24H33N3O4 (427.2470938000001)


Ranolazine is only found in individuals that have used or taken this drug. It is an antianginal medication. On January 31, 2006, ranolazine was approved for use in the United States by the FDA for the treatment of chronic angina. [Wikipedia]The mechanism of action of ranolazine is unknown. It does not increase the rate-pressure product, a measure of myocardial work, at maximal exercise. In vitro studies suggest that ranolazine is a P-gp inhibitor. Ranolazine is believed to have its effects via altering the trans-cellular late sodium current. It is by altering the intracellular sodium level that ranolazine affects the sodium-dependent calcium channels during myocardial ischemia. Thus, ranolazine indirectly prevents the calcium overload that causes cardiac ischemia. C78274 - Agent Affecting Cardiovascular System > C78322 - Cardiotonic Agent D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers C - Cardiovascular system > C01 - Cardiac therapy D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

   

Pimavanserin

Urea, N-((4-fluorophenyl)methyl)-N-(1-methyl-4-piperidinyl)-n-((4-(2-methylpropoxy)phenyl)methyl)-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)

C25H34FN3O2 (427.2634916)


D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.

   

Arachidonoyl ethanolamide phosphate

Arachidonoyl ethanolamide phosphate

C22H38NO5P (427.24874680000005)


   

RANOLAZINE

N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide

C24H33N3O4 (427.2470938000001)


C78274 - Agent Affecting Cardiovascular System > C78322 - Cardiotonic Agent D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers C - Cardiovascular system > C01 - Cardiac therapy D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

   

Gly Pro Arg Val

(2S)-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]-3-methylbutanoic acid

C18H33N7O5 (427.2543048)


   

Gly Pro Val Arg

(2S)-2-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-methylbutanamido]-5-carbamimidamidopentanoic acid

C18H33N7O5 (427.2543048)


   

Gly Arg Pro Val

(2S)-2-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanoic acid

C18H33N7O5 (427.2543048)


   

Gly Arg Val Pro

(2S)-1-[(2S)-2-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanamido]-3-methylbutanoyl]pyrrolidine-2-carboxylic acid

C18H33N7O5 (427.2543048)


   

Gly Val Pro Arg

(2S)-2-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-3-methylbutanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoic acid

C18H33N7O5 (427.2543048)


   

Gly Val Arg Pro

(2S)-1-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-methylbutanamido]-5-carbamimidamidopentanoyl]pyrrolidine-2-carboxylic acid

C18H33N7O5 (427.2543048)


   

Pro Gly Arg Val

(2S)-2-[(2S)-5-carbamimidamido-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}pentanamido]-3-methylbutanoic acid

C18H33N7O5 (427.2543048)


   

Pro Gly Val Arg

(2S)-5-carbamimidamido-2-[(2S)-3-methyl-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}butanamido]pentanoic acid

C18H33N7O5 (427.2543048)


   

Pro Arg Gly Val

(2S)-2-{2-[(2S)-5-carbamimidamido-2-[(2S)-pyrrolidin-2-ylformamido]pentanamido]acetamido}-3-methylbutanoic acid

C18H33N7O5 (427.2543048)


   

Pro Arg Val Gly

2-[(2S)-2-[(2S)-5-carbamimidamido-2-[(2S)-pyrrolidin-2-ylformamido]pentanamido]-3-methylbutanamido]acetic acid

C18H33N7O5 (427.2543048)


   

Pro Val Gly Arg

(2S)-5-carbamimidamido-2-{2-[(2S)-3-methyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]acetamido}pentanoic acid

C18H33N7O5 (427.2543048)


   

Pro Val Arg Gly

2-[(2S)-5-carbamimidamido-2-[(2S)-3-methyl-2-[(2S)-pyrrolidin-2-ylformamido]butanamido]pentanamido]acetic acid

C18H33N7O5 (427.2543048)


   

Arg Gly Pro Val

(2S)-2-{[(2S)-1-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetyl}pyrrolidin-2-yl]formamido}-3-methylbutanoic acid

C18H33N7O5 (427.2543048)


   

Arg Gly Val Pro

(2S)-1-[(2S)-2-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}-3-methylbutanoyl]pyrrolidine-2-carboxylic acid

C18H33N7O5 (427.2543048)


   

Arg Pro Gly Val

(2S)-2-(2-{[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetamido)-3-methylbutanoic acid

C18H33N7O5 (427.2543048)


   

Arg Pro Val Gly

2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}-3-methylbutanamido]acetic acid

C18H33N7O5 (427.2543048)


   

Arg Val Gly Pro

(2S)-1-{2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanamido]acetyl}pyrrolidine-2-carboxylic acid

C18H33N7O5 (427.2543048)


   

Arg Val Pro Gly

2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}acetic acid

C18H33N7O5 (427.2543048)


   

Val Gly Pro Arg

(2S)-2-{[(2S)-1-{2-[(2S)-2-amino-3-methylbutanamido]acetyl}pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoic acid

C18H33N7O5 (427.2543048)


   

Val Gly Arg Pro

(2S)-1-[(2S)-2-{2-[(2S)-2-amino-3-methylbutanamido]acetamido}-5-carbamimidamidopentanoyl]pyrrolidine-2-carboxylic acid

C18H33N7O5 (427.2543048)


   

Val Pro Gly Arg

(2S)-2-(2-{[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]formamido}acetamido)-5-carbamimidamidopentanoic acid

C18H33N7O5 (427.2543048)


   

Val Pro Arg Gly

2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]acetic acid

C18H33N7O5 (427.2543048)


   

Val Arg Gly Pro

(2S)-1-{2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-5-carbamimidamidopentanamido]acetyl}pyrrolidine-2-carboxylic acid

C18H33N7O5 (427.2543048)


   

Val Arg Pro Gly

2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}acetic acid

C18H33N7O5 (427.2543048)


   

Anandamide 0-phosphate

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine-O-phosphate

C22H38NO5P (427.24874680000005)


   

Anandamide O-phosphate

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine-O-phosphate

C22H38NO5P (427.24874680000005)


   

(-)-n-dodecyl-n-methylephedrinium bromide

(-)-n-dodecyl-n-methylephedrinium bromide

C23H42BrNO (427.24495820000004)


   

bis[tris(dimethylamino)-λ5-phosphanylidene]azanium,tetrafluoroborate

bis[tris(dimethylamino)-λ5-phosphanylidene]azanium,tetrafluoroborate

C12H36BF4N7P2 (427.25364740000003)


   

Ivaltinostat

Ivaltinostat

C24H33N3O4 (427.2470938000001)


C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C471 - Enzyme Inhibitor > C1946 - Histone Deacetylase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent

   
   

(2S,3R)-2-[[4-(tert-butylcarbamoyl)piperazine-1-carbonyl]amino]-6-(diaminomethylideneamino)-3-formylhexanoic acid

(2S,3R)-2-[[4-(tert-butylcarbamoyl)piperazine-1-carbonyl]amino]-6-(diaminomethylideneamino)-3-formylhexanoic acid

C18H33N7O5 (427.2543048)


   

4-[(4-Cyclohexyl-1-piperazinyl)-oxomethyl]-2-ethyl-6,7-dimethoxy-1-isoquinolinone

4-[(4-Cyclohexyl-1-piperazinyl)-oxomethyl]-2-ethyl-6,7-dimethoxy-1-isoquinolinone

C24H33N3O4 (427.2470938000001)


   

2-[4-[1-(2-Fluorophenyl)-4-piperidinyl]-1-[(3-methoxyphenyl)methyl]-2-piperazinyl]ethanol

2-[4-[1-(2-Fluorophenyl)-4-piperidinyl]-1-[(3-methoxyphenyl)methyl]-2-piperazinyl]ethanol

C25H34FN3O2 (427.2634916)


   
   

N-(1-cyclohexyl-3-hydroxy-3,4-diphenylbutyl)benzamide

N-(1-cyclohexyl-3-hydroxy-3,4-diphenylbutyl)benzamide

C29H33NO2 (427.25111580000004)


   

N-Benzylidene-1-amino(hepta)ethyleneglycol monomethyl ether

N-Benzylidene-1-amino(hepta)ethyleneglycol monomethyl ether

C22H37NO7 (427.2569892)


   

(2R,3R,3aS,9bS)-N-(cyclohexylmethyl)-1-(2-cyclopropyl-1-oxoethyl)-3-(hydroxymethyl)-6-oxo-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

(2R,3R,3aS,9bS)-N-(cyclohexylmethyl)-1-(2-cyclopropyl-1-oxoethyl)-3-(hydroxymethyl)-6-oxo-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

C24H33N3O4 (427.2470938000001)


   

(2S,3S,3aR,9bR)-N-(cyclohexylmethyl)-1-(2-cyclopropyl-1-oxoethyl)-3-(hydroxymethyl)-6-oxo-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

(2S,3S,3aR,9bR)-N-(cyclohexylmethyl)-1-(2-cyclopropyl-1-oxoethyl)-3-(hydroxymethyl)-6-oxo-3,3a,4,9b-tetrahydro-2H-pyrrolo[2,3-a]indolizine-2-carboxamide

C24H33N3O4 (427.2470938000001)


   

1-[(1S)-2-acetyl-1-(hydroxymethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]-1-butanone

1-[(1S)-2-acetyl-1-(hydroxymethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]-1-butanone

C24H33N3O4 (427.2470938000001)


   

1-[(1R)-2-acetyl-1-(hydroxymethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]-1-butanone

1-[(1R)-2-acetyl-1-(hydroxymethyl)-7-methoxy-9-methyl-1-spiro[1,3-dihydropyrido[3,4-b]indole-4,4-piperidine]yl]-1-butanone

C24H33N3O4 (427.2470938000001)


   

14-(Methoxycarbonyl)-4,4,8alpha,12,16-pentamethyl-3,17-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-dien-15-olate

14-(Methoxycarbonyl)-4,4,8alpha,12,16-pentamethyl-3,17-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-dien-15-olate

C26H35O5- (427.248436)


   

(1R,9S,10S,11S)-12-acetyl-N-(cyclohexylmethyl)-10-(hydroxymethyl)-6-oxo-5-[(Z)-prop-1-enyl]-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

(1R,9S,10S,11S)-12-acetyl-N-(cyclohexylmethyl)-10-(hydroxymethyl)-6-oxo-5-[(Z)-prop-1-enyl]-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C24H33N3O4 (427.2470938000001)


   

(1S,9R,10R,11R)-12-acetyl-N-(cyclohexylmethyl)-10-(hydroxymethyl)-6-oxo-5-[(Z)-prop-1-enyl]-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

(1S,9R,10R,11R)-12-acetyl-N-(cyclohexylmethyl)-10-(hydroxymethyl)-6-oxo-5-[(Z)-prop-1-enyl]-7,12-diazatricyclo[7.2.1.02,7]dodeca-2,4-diene-11-carboxamide

C24H33N3O4 (427.2470938000001)


   

Pimavanserin

Pimavanserin

C25H34FN3O2 (427.2634916)


D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D018726 - Anti-Dyskinesia Agents > D000978 - Antiparkinson Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.

   

andrastin D(1-)

andrastin D(1-)

C26H35O5 (427.248436)


An enolate anion resulting from the deprotonation of the enol of andrastin D.Major species at pH 7.3. Published in http://dx.doi.org/10.1016/j.tet.2013.07.029

   
   
   
   

n-[(2r,3r,4r,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(1s,4r)-1-methyl-4-[(2s)-6-oxoheptan-2-yl]cyclohex-2-en-1-yl]oxy}oxan-3-yl]ethanimidic acid

n-[(2r,3r,4r,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(1s,4r)-1-methyl-4-[(2s)-6-oxoheptan-2-yl]cyclohex-2-en-1-yl]oxy}oxan-3-yl]ethanimidic acid

C22H37NO7 (427.2569892)


   

(3s,6s)-3-({5-[(2s)-2,3-dihydroxy-3-methylbutyl]-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl}methyl)-6-methyl-3,6-dihydropyrazine-2,5-diol

(3s,6s)-3-({5-[(2s)-2,3-dihydroxy-3-methylbutyl]-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl}methyl)-6-methyl-3,6-dihydropyrazine-2,5-diol

C24H33N3O4 (427.2470938000001)


   

n-[4,5-dihydroxy-6-(hydroxymethyl)-2-{[1-methyl-4-(6-oxoheptan-2-yl)cyclohex-2-en-1-yl]oxy}oxan-3-yl]ethanimidic acid

n-[4,5-dihydroxy-6-(hydroxymethyl)-2-{[1-methyl-4-(6-oxoheptan-2-yl)cyclohex-2-en-1-yl]oxy}oxan-3-yl]ethanimidic acid

C22H37NO7 (427.2569892)


   

n-[(2s,3r,4r,5s,6r)-2-({1-[(2r,4s,4ar,8as)-4,7-dimethyl-3,4,4a,5,6,8a-hexahydro-2h-1-benzopyran-2-yl]propan-2-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]ethanimidic acid

n-[(2s,3r,4r,5s,6r)-2-({1-[(2r,4s,4ar,8as)-4,7-dimethyl-3,4,4a,5,6,8a-hexahydro-2h-1-benzopyran-2-yl]propan-2-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]ethanimidic acid

C22H37NO7 (427.2569892)


   

3-{[5-(2,3-dihydroxy-3-methylbutyl)-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]methyl}-6-methyl-3,6-dihydropyrazine-2,5-diol

3-{[5-(2,3-dihydroxy-3-methylbutyl)-2-(2-methylbut-3-en-2-yl)-1h-indol-3-yl]methyl}-6-methyl-3,6-dihydropyrazine-2,5-diol

C24H33N3O4 (427.2470938000001)


   

n-[(2s,3r,4r,5s,6r)-2-({1-[(2s,4s,4ar,8as)-4,7-dimethyl-3,4,4a,5,6,8a-hexahydro-2h-1-benzopyran-2-yl]propan-2-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]ethanimidic acid

n-[(2s,3r,4r,5s,6r)-2-({1-[(2s,4s,4ar,8as)-4,7-dimethyl-3,4,4a,5,6,8a-hexahydro-2h-1-benzopyran-2-yl]propan-2-yl}oxy)-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]ethanimidic acid

C22H37NO7 (427.2569892)