Exact Mass: 422.1537
Exact Mass Matches: 422.1537
Found 345 metabolites which its exact mass value is equals to given mass value 422.1537
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Losartan
Losartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. Losartan and its longer acting metabolite, E-3174, lower blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); they compete with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Losartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure. C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09C - Angiotensin ii receptor blockers (arbs), plain > C09CA - Angiotensin ii receptor blockers (arbs), plain C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C66930 - Angiotensin II Receptor Antagonist COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map D057911 - Angiotensin Receptor Antagonists > D047228 - Angiotensin II Type 1 Receptor Blockers D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents CONFIDENCE standard compound; EAWAG_UCHEM_ID 2794 CONFIDENCE standard compound; INTERNAL_ID 8189 CONFIDENCE standard compound; INTERNAL_ID 8607 CONFIDENCE standard compound; INTERNAL_ID 2280 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
9-Bromo-11beta-hydroxy-16alpha-methylpregn-4-ene-3,20-dione
3-(1,1-Dimethylallyl)scopoletin 7-glucoside
3-(1,1-Dimethylallyl)scopoletin 7-glucoside is found in herbs and spices. 3-(1,1-Dimethylallyl)scopoletin 7-glucoside is a constituent of Ruta graveolens (rue). Constituent of Ruta graveolens (rue). 3-(1,1-Dimethylallyl)scopoletin 7-glucoside is found in herbs and spices.
Riociguat
C - Cardiovascular system > C02 - Antihypertensives > C02K - Other antihypertensives > C02KX - Antihypertensives for pulmonary arterial hypertension C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D020536 - Enzyme Activators
Calealactone B
8alpha-(4-hydroxymethacryloyloxy)-hirsutinolide-13-O-acetate
1alpha-(4-hydroxymethacryloyloxy)-2beta-acetoxy-3alpha,4alpha-epoxy-8alpha-hydroxyeudesm-11(13)-en-6alpha,12-olide
(2R*,4R*,5R*,6S*,8S*,10R*)-1-oxo-2-hydroxy-4,5-epoxy-8-methacryloxy-13-acetoxygermacr-7(11)-en-6,12-olide
alpha,alpha-dihydro-3,3-dihydroxy-5beta-D-O-glucopyranosyloxy-4-methoxystilbene|alpha,beta-dihydrorhaponticin
8alpha-epoxymethacryloyloxy-hirsutinolide-13-O-acetate
6beta-Hydroxyvernopappolid-8-O-methacrylat|8-(2-Methylpropenoyl),13-Ac-6,8,9,13-Tetrahydroxy-1-oxo-4,7(11)-germacradien-12,6-olide
kwansonine A|N2-(1-beta-D-fructopyranosyl)-N5-(2,5-dihydro-2-furyl-3-hydroxymethyl)-gamma-hydroxyglutamine
3(S)-hydroxy-2,2-dimethyl-dihydropyranocoumarin-8-beta-D-glucopyranosyl|corsicarin
4alpha,5beta-epoxy-4-hydroxypectoralide-14-O-acetate
1-Desoxy-8-(2,3-epoxyisobutyryloxy)-10alpha-hydroxyhirsutinolid|8-(2,3-Epoxy-2-mehylpropanoyl)-13-Ac-1,4-Epoxy-8,10,13-trihydroxy-5,7(11)-germacradien-12,6-olide
11,13-dehydrolactuside C|9alpha-hydroxy-11,13-dehydroleucodin-9-O-beta-glucopyranoside
2alpha3beta4alpha-trihydroxy-4beta-(acetoxymethyl)-8alpha(4-methacrylate)-1alphaH,5alphaH,6betaH,7alphaH-guai-10(14),11(13)-dien-6,12-olide
(rel-3R,3aS,9aR)-3,3a,9,9a-tetrahydro-6-hydroxy-3a,8-dimethoxy-3,7,9a-trimethyl-1-oxo-5-(1-oxobutyl)-1H-furo-[3,4-b]-1-benzopyran-3-carboxylic acid|pallenic acid
2alpha-hydroxycyclohex-4-en-1beta-yl 2-O-[(Z)-p-coumaroyl]-beta-D-glucopyranoside
15-deschloro-3beta-acetoxy-15-hydroxychlorojanerin
1beta,10alpha-epoxy-4-hydroxypectoralide-14-O-acetate
C21H26O9_(1aS,3R,4R,5S,5aS,8aR,10R,10aS)-4-Acetoxy-3-hydroxy-3,10-dimethyl-6-methylene-2,7-dioxododecahydrooxireno[7,8]cyclodeca[1,2-b]furan-5-yl methacrylate
losartan
C - Cardiovascular system > C09 - Agents acting on the renin-angiotensin system > C09C - Angiotensin ii receptor blockers (arbs), plain > C09CA - Angiotensin ii receptor blockers (arbs), plain C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C66930 - Angiotensin II Receptor Antagonist COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, COVID-19 Disease Map D057911 - Angiotensin Receptor Antagonists > D047228 - Angiotensin II Type 1 Receptor Blockers D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
(1R,3R,4S,6S,8R,9R,10S,11S)-9-(acetyloxy)-8-hydroxy-3,8-dimethyl-12-methylidene-7,13-dioxo-5,14-dioxatricyclo[9.3.0.0⁴,⁶]tetradecan-10-yl 2-methylprop-2-enoate
(1R,3R,4S,6S,8R,9R,10S,11S)-9-(acetyloxy)-8-hydroxy-3,8-dimethyl-12-methylidene-7,13-dioxo-5,14-dioxatricyclo[9.3.0.0⁴,⁶]tetradecan-10-yl 2-methylprop-2-enoate_major
Ala Cys Glu Thr
Ala Cys Thr Glu
Loxoprofen Metabolite (b-D-Glucopyranuronic acid, 1-[a-methyl-4-[(2-oxocyclopentyl)methyl]benzeneace
Ala Asp Met Ser
Ala Asp Ser Met
Ala Glu Cys Thr
Ala Glu Thr Cys
Ala Met Asp Ser
Ala Met Ser Asp
Ala Ser Asp Met
Ala Ser Met Asp
Ala Thr Cys Glu
Ala Thr Glu Cys
Cys Ala Glu Thr
Cys Ala Thr Glu
Cys Asp Ser Val
Cys Asp Val Ser
Cys Glu Ala Thr
Cys Glu Thr Ala
Cys Phe Gly Pro
Cys Phe Pro Gly
Cys Gly Phe Pro
Cys Gly Pro Phe
Cys Pro Phe Gly
Cys Pro Gly Phe
Cys Ser Asp Val
Cys Ser Val Asp
Cys Thr Ala Glu
Cys Thr Glu Ala
Cys Val Asp Ser
Cys Val Ser Asp
Asp Ala Met Ser
Asp Ala Ser Met
Asp Cys Ser Val
Asp Cys Val Ser
Asp Gly Met Thr
Asp Gly Thr Met
Asp Met Ala Ser
Asp Met Gly Thr
Asp Met Ser Ala
Asp Met Thr Gly
Asp Ser Ala Met
Asp Ser Cys Val
Asp Ser Met Ala
Asp Ser Val Cys
Asp Thr Gly Met
Asp Thr Met Gly
Asp Val Cys Ser
Asp Val Ser Cys
Glu Ala Cys Thr
Glu Ala Thr Cys
Glu Cys Ala Thr
Glu Cys Thr Ala
Glu Gly Met Ser
Glu Gly Ser Met
Glu Met Gly Ser
Glu Met Ser Gly
Glu Ser Gly Met
Glu Ser Met Gly
Glu Thr Ala Cys
Glu Thr Cys Ala
Phe Cys Gly Pro
Phe Cys Pro Gly
Phe Gly Cys Pro
Phe Gly Pro Cys
Phe Pro Cys Gly
Phe Pro Gly Cys
Gly Cys Phe Pro
Gly Cys Pro Phe
Gly Asp Met Thr
Gly Asp Thr Met
Gly Glu Met Ser
Gly Glu Ser Met
Gly Phe Cys Pro
Gly Phe Pro Cys
Gly Met Asp Thr
Gly Met Glu Ser
Gly Met Ser Glu
Gly Met Thr Asp
Gly Pro Cys Phe
Gly Pro Phe Cys
Gly Ser Glu Met
Gly Ser Met Glu
Gly Thr Asp Met
Gly Thr Met Asp
Met Ala Asp Ser
Met Ala Ser Asp
Met Asp Ala Ser
Met Asp Gly Thr
Met Asp Ser Ala
Met Asp Thr Gly
Met Glu Gly Ser
Met Glu Ser Gly
Met Gly Asp Thr
Met Gly Glu Ser
Met Gly Ser Glu
Met Gly Thr Asp
Met Ser Ala Asp
Met Ser Asp Ala
Met Ser Glu Gly
Met Ser Gly Glu
Met Thr Asp Gly
Met Thr Gly Asp
Pro Cys Phe Gly
Pro Cys Gly Phe
Pro Phe Cys Gly
Pro Phe Gly Cys
Pro Gly Cys Phe
Pro Gly Phe Cys
Ser Ala Asp Met
Ser Ala Met Asp
Ser Cys Asp Val
Ser Cys Val Asp
Ser Asp Ala Met
Ser Asp Cys Val
Ser Asp Met Ala
Ser Asp Val Cys
Ser Glu Gly Met
Ser Glu Met Gly
Ser Gly Glu Met
Ser Gly Met Glu
Ser Met Ala Asp
Ser Met Asp Ala
Ser Met Glu Gly
Ser Met Gly Glu
Ser Val Cys Asp
Ser Val Asp Cys
Thr Ala Cys Glu
Thr Ala Glu Cys
Thr Cys Ala Glu
Thr Cys Glu Ala
Thr Asp Gly Met
Thr Asp Met Gly
Thr Glu Ala Cys
Thr Glu Cys Ala
Thr Gly Asp Met
Thr Gly Met Asp
Thr Met Asp Gly
Thr Met Gly Asp
Val Cys Asp Ser
Val Cys Ser Asp
Val Asp Cys Ser
Val Asp Ser Cys
Val Ser Cys Asp
Val Ser Asp Cys
3-(1,1-Dimethylallyl)scopoletin 7-glucoside
[2-butyl-5-chloro-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
3-[5-(3-METHYL-5-ISOXAZOLYL)-2-(METHYLSULFONYL)-4-PYRIMIDINYL]-1-PIPERIDINECARBOXYLIC ACID,1,1-DIMETHYLETHYL ESTER
olodaterol hydrochloride
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents Olodaterol (BI1744) hydrochloride is a selective, long acting β2-adrenoceptor (β2-AR) agonist (EC50=0.1 nM and pKi= 9.14 for human β2-adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis[1][2][3].
1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D065147 - Viral Fusion Protein Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents D065147 - Viral Fusion Protein Inhibitors > D023581 - HIV Fusion Inhibitors
Mavatrep
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
Izonsteride
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C242 - Anti-Androgen C471 - Enzyme Inhibitor > C2319 - 5 Alpha-Reductase Inhibitor C1892 - Chemopreventive Agent
9-(3-(3,5-Dinitrobenzoylamino)propyl)-1,2,3,4-tetrahydrocarbazole
2-Hydroxy-5-({1-[(2-Naphthyloxy)Methyl]-3-Oxoprop-1-Enyl}Amino)Tyrosine
Riociguat
C - Cardiovascular system > C02 - Antihypertensives > C02K - Other antihypertensives > C02KX - Antihypertensives for pulmonary arterial hypertension C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent D020536 - Enzyme Activators
2-amino-4-[3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-methyl-9-oxo-5H-imidazo[1,2-a]purin-7-yl]butanoic acid
3-[[1-(dimethylsulfamoyl)-4-piperidinyl]oxy]-N-[(3-methyl-5-isoxazolyl)methyl]benzamide
2-acetamido-2-deoxy-alpha-L-galactopyranuronosyl-(1->3)-N-acetyl-D-quinovosamine
A disaccharide formed by an alpha1->3 glycosidic linkage between N-acetyl-L-galactosaminuronic acid and N-acetylquinovosamine.
5-[6-hydroxy-2-phenyl-4-[(E)-2-phenylethenyl]-2,3-dihydro-1-benzouran-3-yl]benzene-1,3-diol
CID 5702111
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D018373 - Peripheral Nervous System Agents > D009465 - Neuromuscular Agents D002491 - Central Nervous System Agents > D000700 - Analgesics