Exact Mass: 421.00954480000007

Exact Mass Matches: 421.00954480000007

Found 6 metabolites which its exact mass value is equals to given mass value 421.00954480000007, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

   

5-IODO-3-INDOLYL-β -D-GALACTOPYRANOSI

5-IODO-3-INDOLYL-β -D-GALACTOPYRANOSI

C14H16INO6 (421.0022346)


   

6-chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide

6-chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide

C18H13Cl2N3O3S (421.0054648)


   

5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide

5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide

C18H17BrClN3O2 (421.0192592)


   

2-(2,6-Dichlorophenyl)acetic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] ester

2-(2,6-Dichlorophenyl)acetic acid [2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl] ester

C17H12Cl2F3NO4 (421.00954480000007)


   

VU 0364439

VU 0364439

C18H13Cl2N3O3S (421.0054648)


VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM. IC50 Value: 19.8 nM(EC50) Target: mGluR in vitro: in vivo: VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63\% remaining) than RLM (2\% remaining).