Exact Mass: 419.0250680000001

Exact Mass Matches: 419.0250680000001

Found 2 metabolites which its exact mass value is equals to given mass value 419.0250680000001, within given mass tolerance error 1.6E-6 dalton. Try search metabolite list with more accurate mass tolerance error 3.2E-7 dalton.

(Rac)-PT2399

(Rac)-PT2399

C17H10F5NO4S (419.0250680000001)


(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM[1].

   

PT2399

PT2399

C17H10F5NO4S (419.0250680000001)


PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC50 of 6 nM. PT2399 displays potent antitumor activity in vivo[1][2][3].