Exact Mass: 414.2031

Exact Mass Matches: 414.2031

Found 1 metabolites which its exact mass value is equals to given mass value 414.2031, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

JNJ-46281222

JNJ-46281222

C23H25F3N4 (414.2031)


JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator) with nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50?= 7.71)[1].