Exact Mass: 414.2031

Exact Mass Matches: 414.2031

Found 1 metabolites which its exact mass value is equals to given mass value 414.2031, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

JNJ-46281222

JNJ-46281222

C23H25F3N4 (414.2031)


JNJ-46281222 is an metabotropic glutamate (mGlu) 2-selective, highly potent PAM (positive allosteric modulator) with nanomolar affinity (Kd = 1.7 nM) and a high modulatory potency (pEC50?= 7.71)[1].