Exact Mass: 410.14712760000003

Exact Mass Matches: 410.14712760000003

Found 30 metabolites which its exact mass value is equals to given mass value 410.14712760000003, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Darusentan

2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid

C22H22N2O6 (410.1477792)

Cys Ser Thr Thr

(2S,3R)-2-[(2S,3R)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]-3-hydroxybutanoic acid

C14H26N4O8S (410.14712760000003)

Cys Thr Ser Thr

(2S,3R)-2-[(2S)-2-[(2S,3R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]-3-hydroxybutanoic acid

C14H26N4O8S (410.14712760000003)

Cys Thr Thr Ser

(2S)-2-[(2S,3R)-2-[(2S,3R)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-hydroxypropanoic acid

C14H26N4O8S (410.14712760000003)

Met Ser Ser Ser

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-4-(methylsulfanyl)butanamido]-3-hydroxypropanamido]-3-hydroxypropanamido]-3-hydroxypropanoic acid

C14H26N4O8S (410.14712760000003)

Ser Cys Thr Thr

(2S,3R)-2-[(2S,3R)-2-[(2R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]-3-hydroxybutanoic acid

C14H26N4O8S (410.14712760000003)

Ser Met Ser Ser

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]-3-hydroxypropanamido]-3-hydroxypropanoic acid

C14H26N4O8S (410.14712760000003)

Ser Ser Met Ser

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanamido]-3-hydroxypropanoic acid

C14H26N4O8S (410.14712760000003)

Ser Ser Ser Met

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxypropanamido]-3-hydroxypropanamido]-4-(methylsulfanyl)butanoic acid

C14H26N4O8S (410.14712760000003)

Ser Thr Cys Thr

(2S,3R)-2-[(2R)-2-[(2S,3R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxybutanamido]-3-sulfanylpropanamido]-3-hydroxybutanoic acid

C14H26N4O8S (410.14712760000003)

Ser Thr Thr Cys

(2R)-2-[(2S,3R)-2-[(2S,3R)-2-[(2S)-2-amino-3-hydroxypropanamido]-3-hydroxybutanamido]-3-hydroxybutanamido]-3-sulfanylpropanoic acid

C14H26N4O8S (410.14712760000003)

Thr Cys Ser Thr

(2S,3R)-2-[(2S)-2-[(2R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-sulfanylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanoic acid

C14H26N4O8S (410.14712760000003)

Thr Cys Thr Ser

(2S)-2-[(2S,3R)-2-[(2R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-sulfanylpropanamido]-3-hydroxybutanamido]-3-hydroxypropanoic acid

C14H26N4O8S (410.14712760000003)

Thr Ser Cys Thr

(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxypropanamido]-3-sulfanylpropanamido]-3-hydroxybutanoic acid

C14H26N4O8S (410.14712760000003)

Thr Ser Thr Cys

(2R)-2-[(2S,3R)-2-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]-3-sulfanylpropanoic acid

C14H26N4O8S (410.14712760000003)

Thr Thr Cys Ser

(2S)-2-[(2R)-2-[(2S,3R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxybutanamido]-3-sulfanylpropanamido]-3-hydroxypropanoic acid

C14H26N4O8S (410.14712760000003)

Thr Thr Ser Cys

(2R)-2-[(2S)-2-[(2S,3R)-2-[(2S,3R)-2-amino-3-hydroxybutanamido]-3-hydroxybutanamido]-3-hydroxypropanamido]-3-sulfanylpropanoic acid

C14H26N4O8S (410.14712760000003)

Darusentan

C22H22N2O6 (410.1477792)

C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent D065128 - Endothelin Receptor Antagonists C28313 - Endothelin Receptor Antagonist Darusentan (Lu-135252) is a selective endothelin receptor A (ET-A) receptor antagonist, which binds with a Ki of 1.4 nM to the ET-A receptor and a Ki of 184 nM to ET-B receptor, respectively with a 100-fold selectivity for ETA rather than ETB receptors[1]. Darusentan competes for radiolabeled endothelin binding in rat aortic vascular smooth muscle cells (RAVSMs) membranes with single-site kinetics, exhibiting a Ki of 13 nM[2].

4-(4-PROPYLCYCLOHEXYL)CYCLOHEXYLPHENYL IODIDE

C21H31I (410.14703959999997)

Fmoc-Dap(Alloc)-OH

C22H22N2O6 (410.1477792)

Darusentan, (+/-)-

C22H22N2O6 (410.1477792)

3-(4-fluorophenyl)-4,4,6,8-tetramethyl-5,6-dihydro-4H,4H-spiro[pyrrolo[3,2,1-ij]quinoline-1,2-[1,3]thiazolidine]-2,4-dione

C23H23FN2O2S (410.146419)

(2S)-2-[12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid

C22H22N2O6 (410.1477792)

SN-38 carboxylic acid

C22H22N2O6 (410.1477792)

A 2-hydroxy monocarboxylic acid resulting from the hydrolysis of the delta-lactone ring of SN-38. It is a metabolite of SN-38.

MMV009085

C22H22N2O6 (410.1477792)

MMV009085 is a potent PfHT1 (Plasmodium?falciparum?hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7)[1].

methyl (1r,9r,10r,12r)-4-methoxy-15,20-dioxo-19-oxa-8,16-diazahexacyclo[8.8.2.2⁹,¹².0¹,⁹.0²,⁷.0¹²,¹⁶]docosa-2,4,6,13-tetraene-8-carboxylate

C22H22N2O6 (410.1477792)

methyl (1s,12r,19r,21r,24r)-21-hydroxy-20-oxo-5,7-dioxa-2,15-diazaheptacyclo[17.2.2.1¹²,¹⁵.0¹,¹².0³,¹¹.0⁴,⁸.0¹⁹,²⁴]tetracosa-3,8,10,17-tetraene-21-carboxylate

C22H22N2O6 (410.1477792)