Exact Mass: 409.1492

Exact Mass Matches: 409.1492

Found 29 metabolites which its exact mass value is equals to given mass value 409.1492, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Ezetimibe

(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one

C24H21F2NO3 (409.1489)


Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes. D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent D009676 - Noxae > D000963 - Antimetabolites Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.

   

(3R,4S)-1-(4-Fluorophenyl)-4-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-Fluorophenyl)-4-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)azetidin-2-one

C24H21F2NO3 (409.1489)


   

Fluoxetine Succinamic Acid

Fluoxetine Succinamic Acid

C21H22F3NO4 (409.1501)


CONFIDENCE Tentative identification: most likely structure (Level 3); INTERNAL_ID 702

   
   
   
   
   
   
   

Ezetimibe

Ezetimibe

C24H21F2NO3 (409.1489)


D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent D009676 - Noxae > D000963 - Antimetabolites Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.

   

Thioridazine-d3 (hydrochloride)

Thioridazine-d3 (hydrochloride)

C21H24ClD3N2S2 (409.1492)


   

Ezetimibe Tetrahydropyran Impurity

Ezetimibe Tetrahydropyran Impurity

C24H21F2NO3 (409.1489)


   
   

[2-(diethylcarbamoyl)-4-(2,4-difluorophenyl)phenyl] benzoate

[2-(diethylcarbamoyl)-4-(2,4-difluorophenyl)phenyl] benzoate

C24H21F2NO3 (409.1489)


   

(3S)-ent-Ezetimibe

(3S)-ent-Ezetimibe

C24H21F2NO3 (409.1489)


   

ent-Ezetimibe

ent-Ezetimibe

C24H21F2NO3 (409.1489)


ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent?Nrf2 activator[1].

   

Ezetimibe 3-Fluoro Impurity

Ezetimibe 3-Fluoro Impurity

C24H21F2NO3 (409.1489)


   

trans-1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

trans-1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

C24H21F2NO3 (409.1489)


   

1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

C24H21F2NO3 (409.1489)


   

N-[4-({[5-(Dimethylamino)-1-Naphthyl]sulfonyl}amino)butyl]-3-Sulfanylpropanamide

N-[4-({[5-(Dimethylamino)-1-Naphthyl]sulfonyl}amino)butyl]-3-Sulfanylpropanamide

C19H27N3O3S2 (409.1494)


   

(3R,4S)-1-(4-Fluorophenyl)-4-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)azetidin-2-one

(3R,4S)-1-(4-Fluorophenyl)-4-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-3-(4-hydroxyphenyl)azetidin-2-one

C24H21F2NO3 (409.1489)