Ezetimibe (BioDeep_00000018453)
human metabolite blood metabolite Chemicals and Drugs
代谢物信息卡片
(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
化学式: C24H21F2NO3 (409.1489)
中文名称: 依泽替米贝
谱图信息:
最多检出来源 Homo sapiens(blood) 40.06%
分子结构信息
SMILES: C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
InChI: InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1
描述信息
Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.
D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents
C - Cardiovascular system > C10 - Lipid modifying agents > C10A - Lipid modifying agents, plain
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
D009676 - Noxae > D000963 - Antimetabolites
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
同义名列表
11 个代谢物同义名
(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; (1-(4-Fluorophenyl)-(3R)-(3-(4-fluorophenyl)-(3S)-hydroxypropyl)-(4S)-(4-hydroxyphenyl)-2-azetidinone); (3R)-Ezetimibe; Ezetimibum; Ezetimiba; Ezetimibe; Ezetimib; Ezetrol; Ezedoc; Zetia; SCH 58235
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:49040
- PubChem: 150311
- HMDB: HMDB0015108
- DrugBank: DB00973
- ChEMBL: CHEMBL1138
- Wikipedia: Ezetimibe
- MeSH: Ezetimibe
- chemspider: 132493
- CAS: 163222-33-1
- PMhub: MS000008145
- medchemexpress: HY-17376
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
6 个相关的代谢反应过程信息。
Reactome(6)
- Digestion and absorption:
H2O + limit dextrin ⟶ Glc + Mal + maltotriose - Intestinal absorption:
EZE + Homologues of NPC1L1-1 ⟶ NPC1L1:ezetimibe complex - Intestinal lipid absorption:
EZE + Homologues of NPC1L1-1 ⟶ NPC1L1:ezetimibe complex - Digestion and absorption:
H2O + limit dextrin ⟶ Glc + Mal + maltotriose - Intestinal absorption:
EZE + NPC1L1-1 ⟶ NPC1L1:ezetimibe complex - Intestinal lipid absorption:
EZE + NPC1L1-1 ⟶ NPC1L1:ezetimibe complex
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Wolfgang Koenig, Elke S Lorenz, Lea Beier, Ioanna Gouni-Berthold. Retrospective real-world analysis of adherence and persistence to lipid-lowering therapy in Germany.
Clinical research in cardiology : official journal of the German Cardiac Society.
2024 Jun; 113(6):812-821. doi:
10.1007/s00392-023-02257-6. [PMID: 37603070] - Lusheng Miao, Taosheng Miao, Ying Zhang, Jin Hao. Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study.
BMC cancer.
2024 May; 24(1):602. doi:
10.1186/s12885-024-12366-8. [PMID: 38760735] - Ishaque Hameed, Syeda Ayesha Shah, Ashnah Aijaz, Hasan Mushahid, Syed Husain Farhan, Muhammad Dada, Adam Bilal Khan, Reeha Amjad, Fawad Alvi, Mustafa Murtaza, Zaid Zuberi, Mohammad Hamza. Comparative Safety and Efficacy of Low/Moderate-Intensity Statin plus Ezetimibe Combination Therapy vs. High-Intensity Statin Monotherapy in Patients with Atherosclerotic Cardiovascular Disease: An Updated Meta-Analysis.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
2024 May; 24(3):419-431. doi:
10.1007/s40256-024-00642-8. [PMID: 38578578] - Frederick J Raal, Robert A Hegele, Andrea Ruzza, J Antonio G López, Ajay K Bhatia, Johnny Wu, Huei Wang, Daniel Gaudet, Albert Wiegman, Jian Wang, Raul D Santos. Evolocumab Treatment in Pediatric Patients With Homozygous Familial Hypercholesterolemia: Pooled Data From Three Open-Label Studies.
Arteriosclerosis, thrombosis, and vascular biology.
2024 May; 44(5):1156-1164. doi:
10.1161/atvbaha.123.320268. [PMID: 38545781] - Chanho Lee, Se Hyun Kwak, Jisu Han, Ju Hye Shin, Byunghun Yoo, Yu Seol Lee, Jeong Su Park, Beom Jin Lim, Jin Gu Lee, Young Sam Kim, Song Yee Kim, Soo Han Bae. Repositioning of ezetimibe for the treatment of idiopathic pulmonary fibrosis.
The European respiratory journal.
2024 May; 63(5):. doi:
10.1183/13993003.00580-2023. [PMID: 38359963] - Ching-Chih Chang, Hui-Chun Huang, Shao-Jung Hsu, Chon-Kit Pun, Chiao-Lin Chuang, Ming-Chih Hou, Fa-Yauh Lee. Ezetimibe treatment reduces oxidized low-density lipoprotein in biliary cirrhotic rats.
Journal of the Chinese Medical Association : JCMA.
2024 May; 87(5):463-470. doi:
10.1097/jcma.0000000000001075. [PMID: 38380910] - Xuxian Lv, Xudong Liu, Yanfang Peng, Wenbin Li, Jianing Wang, Xiaofeng Chen, Junjie Lei, Chaogang Tang, Shijian Luo, Weihua Mai, Yiming Cai, Qian Fan, Chenhao Liu, Lei Zhang. Medium-intensity statin with ezetimibe versus high-intensity statin in acute ischemic cerebrovascular disease (MESIA): A randomized clinical trial.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.
2024 May; 33(5):107647. doi:
10.1016/j.jstrokecerebrovasdis.2024.107647. [PMID: 38431112] - Antoine Fayol, François Schiele, Jean Ferrières, Etienne Puymirat, Vincent Bataille, Victoria Tea, Chekrallah Chamandi, Franck Albert, Gilles Lemesle, Guillaume Cayla, Orianne Weizman, Tabassome Simon, Nicolas Danchin. Association of Use and Dose of Lipid-Lowering Therapy Post Acute Myocardial Infarction With 5-Year Survival in Older Adults.
Circulation. Cardiovascular quality and outcomes.
2024 May; 17(5):e010685. doi:
10.1161/circoutcomes.123.010685. [PMID: 38682335] - Nimish N Shah, Lama Ghazi, Yu Yamamoto, Sanchit Kumar, Melissa Martin, Michael Simonov, Ralph J Riello Iii, Kamil F Faridi, Tariq Ahmad, F Perry Wilson, Nihar R Desai. Pragmatic Trial of Messaging to Providers About Treatment of Hyperlipidemia (PROMPT-LIPID): A Randomized Clinical Trial.
Circulation. Cardiovascular quality and outcomes.
2024 May; 17(5):e010335. doi:
10.1161/circoutcomes.123.010335. [PMID: 38634282] - Furio Colivicchi, Marcello Arca, Stefania Angela Di Fusco, Angela Pirillo, Alberico L Catapano. [STEP-RCV Project - A scientific expert panel for patients at high and very high cardiovascular risk: how to streamline lipid-lowering therapy].
Giornale italiano di cardiologia (2006).
2024 May; 25(5):318-326. doi:
10.1714/4252.42295. [PMID: 38639122] - Noel Peretti, Alexandre Vimont, Emmanuel Mas, Julie Lemale, Rachel Reynaud, Patrick Tounian, Pierre Poinsot, Liora Restier, François Paillard, Alain Pradignac, Yann Pucheu, Jean-Pierre Rabès, Eric Bruckert, Antonio Gallo, Sophie Béliard. Treatment of pediatric heterozygous familial hypercholesterolemia 7 years after the EAS recommendations: Real-world results from a large French cohort.
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.
2024 Apr; 31(3):188-194. doi:
10.1016/j.arcped.2024.01.004. [PMID: 38538465] - Sining Xie, Federica Galimberti, Elena Olmastroni, Thomas F Luscher, Stefano Carugo, Alberico L Catapano, Manuela Casula. Effect of lipid-lowering therapies on C-reactive protein levels: a comprehensive meta-analysis of randomized controlled trials.
Cardiovascular research.
2024 Mar; 120(4):333-344. doi:
10.1093/cvr/cvae034. [PMID: 38373008] - Xiangqi Kong, Gang He, Xiaoqing Quan, Zhixiong Tan, Fengjuan Yan, Xiehui Chen. The impact of the 2019 ESC/EAS dyslipidaemia guidelines on real-world initial lipid-lowering therapy in patients with acute myocardial infarction.
Medicine.
2024 Mar; 103(12):e37637. doi:
10.1097/md.0000000000037637. [PMID: 38517999] - Rui Gu, Hui Wang, Chun-Lin Wang, Mei Lu, Miao Miao, Meng-Na Huang, Yi Chen, Yang-Li Dai, Ming-Qiang Zhu, Qiong Zhou, Chao-Chun Zou. Gene variants and clinical characteristics of children with sitosterolemia.
Lipids in health and disease.
2024 Mar; 23(1):83. doi:
10.1186/s12944-024-02077-1. [PMID: 38509578] - Satyavir Yadav, Jitendra Pal Singh Sawhney. Treatment of dyslipidemia in acute coronary syndrome.
Indian heart journal.
2024 Mar; 76 Suppl 1(?):S51-S57. doi:
10.1016/j.ihj.2024.01.011. [PMID: 38307382] - Ashwani Mehta. Managing dyslipidaemia in patients with chronic kidney disease.
Indian heart journal.
2024 Mar; 76 Suppl 1(?):S90-S92. doi:
10.1016/j.ihj.2024.01.012. [PMID: 38278323] - Liang Qiao, Shun Lv, Kai Meng, Jianmei Yang. Genetically proxied therapeutic inhibition of lipid-lowering drug targets and risk of rheumatoid arthritis disease: a Mendelian randomization study.
Clinical rheumatology.
2024 Mar; 43(3):939-947. doi:
10.1007/s10067-023-06837-9. [PMID: 38198113] - Lauren E Passero, Megan C Roberts. Measuring Costs of Cardiovascular Disease Prevention for Patients with Familial Hypercholesterolemia in Administrative Claims Data.
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension.
2024 Mar; 31(2):215-219. doi:
10.1007/s40292-024-00624-6. [PMID: 38308804] - Sylvain Bétrisey, Moa Lina Haller, Orestis Efthimiou, Alexandre Speierer, Cinzia Del Giovane, Elisavet Moutzouri, Manuel R Blum, Drahomir Aujesky, Nicolas Rodondi, Baris Gencer. Lipid-Lowering Therapy and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Journal of the American Heart Association.
2024 Feb; 13(4):e030714. doi:
10.1161/jaha.123.030714. [PMID: 38323514] - Masanari Kuwabara, Jun Sasaki, Yasuyoshi Ouchi, Shinichi Oikawa, Kiyotaka Nakagawa, Masao Sato, Shinji Koba, Suminori Kono, Tetsunori Saikawa, Hidenori Arai. Higher Cholesterol Absorption Marker at Baseline Predicts Fewer Cardiovascular Events in Elderly Patients Receiving Hypercholesterolemia Treatment: The KEEP Study.
Journal of the American Heart Association.
2024 Feb; 13(3):e031865. doi:
10.1161/jaha.123.031865. [PMID: 38240241] - Christoph Ebenbichler, Heinz Drexel, Ursula Hanusch, Hermann Toplak, Nafeesa N Dhalwani, Ian Bridges, Robert Hoelzl, Margit Hemetsberger, Kausik K Ray. Evolocumab effectiveness in the real-world setting: Austrian data from the pan-European observational HEYMANS study.
Wiener klinische Wochenschrift.
2024 Feb; 136(3-4):77-86. doi:
10.1007/s00508-023-02245-w. [PMID: 37525072] - John J P Kastelein, Andrew Hsieh, Mary R Dicklin, Marc Ditmarsch, Michael H Davidson. Obicetrapib: Reversing the Tide of CETP Inhibitor Disappointments.
Current atherosclerosis reports.
2024 Feb; 26(2):35-44. doi:
10.1007/s11883-023-01184-1. [PMID: 38133847] - Awad Alshahrani, Naji Kholaif, Mutaz Al-Khnifsawi, Hawazen Zarif, Moeber Mahzari. The Effect of PCSK9 Inhibitors on LDL-C Target Achievement in Patients with Homozygous Familial Hypercholesterolemia: A Retrospective Cohort Analysis.
Advances in therapy.
2024 Feb; 41(2):837-846. doi:
10.1007/s12325-023-02764-y. [PMID: 38169062] - Michishige Terasaki, Mikiko Izumi, Sho-Ichi Yamagishi. A Clinical Case of Probable Sitosterolemia.
International journal of molecular sciences.
2024 Jan; 25(3):. doi:
10.3390/ijms25031535. [PMID: 38338819] - Julius L Katzmann, Paulina E Stürzebecher, Silvia Kruppert, Ulrich Laufs. LDL cholesterol target attainment in cardiovascular high- and very-high-risk patients with statin intolerance: a simulation study.
Scientific reports.
2024 01; 14(1):474. doi:
10.1038/s41598-023-50847-1. [PMID: 38172531] - Francesco Sbrana, Beatrice Dal Pino, Federico Bigazzi, Tiziana Sampietro. Widespread xanthomas regression by personalized lipid lowering therapy in heterozygous familial hypercholesterolemia.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis.
2024 Jan; 36(1):35-37. doi:
10.1016/j.arteri.2023.11.002. [PMID: 38016879] - Isabella Sudano, Stephan Krähenbühl, François Mach, Anne Anstett, Nafeesa Dhalwani, Ian Bridges, Mahendra Sibartie, Kausik K Ray. Evolocumab use in clinical practice in Switzerland: final data of the observational HEYMANS cohort study.
Therapeutic advances in cardiovascular disease.
2024 Jan; 18(?):17539447231213288. doi:
10.1177/17539447231213288. [PMID: 38183273] - Daniel A Gomes, Mariana Sousa Paiva, Pedro Freitas, Francisco Albuquerque, Maria Rita Lima, Rita Reis Santos, João Presume, Marisa Trabulo, Carlos Aguiar, Jorge Ferreira, António M Ferreira, Miguel Mendes. Attainment of LDL-Cholesterol Goals in Patients with Previous Myocardial Infarction: A Real-World Cross-Sectional Analysis.
Arquivos brasileiros de cardiologia.
2024; 121(1):e20230242. doi:
10.36660/abc.20230242. [PMID: 38477763] - Ji Hye Han, Kyong Hye Joung, Jun Choul Lee, Ok Soon Kim, Sorim Choung, Ji Min Kim, Yea Eun Kang, Hyon-Seung Yi, Ju Hee Lee, Bon Jeong Ku, Hyun Jin Kim. Comparative Efficacy of Rosuvastatin Monotherapy and Rosuvastatin/Ezetimibe Combination Therapy on Insulin Sensitivity and Vascular Inflammatory Response in Patients with Type 2 Diabetes Mellitus.
Diabetes & metabolism journal.
2024 Jan; 48(1):112-121. doi:
10.4093/dmj.2022.0402. [PMID: 38173371] - Heinz Drexel, Arthur Mader. Bempedoic Acid: How Will It Shape the Future Lipid-Lowering Landscape? Mode of Action, Evidence, and Clinical Use.
Cardiology.
2024; 149(1):71-77. doi:
10.1159/000535372. [PMID: 37989119] - Lucy Bolt, Alexandre Speierer, Sylvain Bétrisey, Martina Aeschbacher-Germann, Manuel R Blum, Baris Gencer, Cinzia Del Giovane, Drahomir Aujseky, Elisavet Moutzouri, Nicolas Rodondi. Is there a shift from cardiovascular to cancer death in lipid-lowering trials? A systematic review and meta-analysis.
PloS one.
2024; 19(2):e0297852. doi:
10.1371/journal.pone.0297852. [PMID: 38329982] - Jedidiah I Morton, Clara Marquina, Melanie Lloyd, Gerald F Watts, Sophia Zoungas, Danny Liew, Zanfina Ademi. Lipid-Lowering Strategies for Primary Prevention of Coronary Heart Disease in the UK: A Cost-Effectiveness Analysis.
PharmacoEconomics.
2024 Jan; 42(1):91-107. doi:
10.1007/s40273-023-01306-2. [PMID: 37606881] - Yura Kang, Jung Mi Park, Sang-Hak Lee. Moderate-Intensity Rosuvastatin/Ezetimibe Combination versus Quadruple-Dose Rosuvastatin Monotherapy: A Meta-Analysis and Systemic Review.
Yonsei medical journal.
2024 Jan; 65(1):19-26. doi:
10.3349/ymj.2023.0285. [PMID: 38154476] - Sang-Hyeon Ju, Joung Youl Lim, Minchul Song, Ji Min Kim, Yea Eun Kang, Hyon-Seung Yi, Kyong Hye Joung, Ju Hee Lee, Hyun Jin Kim, Bon Jeong Ku. Distinct effects of rosuvastatin and rosuvastatin/ezetimibe on senescence markers of CD8+ T cells in patients with type 2 diabetes mellitus: a randomized controlled trial.
Frontiers in endocrinology.
2024; 15(?):1336357. doi:
10.3389/fendo.2024.1336357. [PMID: 38586464] - Zhiquan Wang, Zhe Wang, Miao Lin, Bowen Zheng, Jinlan Zhang. A study on cholesterol-cholesteryl ester metabolic homeostasis and drug intervention in hyperlipidemic hamsters using UHPLC-MS/MS.
Journal of pharmaceutical and biomedical analysis.
2023 Dec; 240(?):115933. doi:
10.1016/j.jpba.2023.115933. [PMID: 38154368] - Yuting Yin, Chun Wu, Yufeng Zhou, Meiyin Zhang, Shijuan Mai, Minshan Chen, Hui-Yun Wang. Ezetimibe Induces Paraptosis through Niemann-Pick C1-like 1 Inhibition of Mammalian-Target-of-Rapamycin Signaling in Hepatocellular Carcinoma Cells.
Genes.
2023 Dec; 15(1):. doi:
10.3390/genes15010004. [PMID: 38275586] - Achim Leo Burger, Nora Beran, Edita Pogran, Christoph C Kaufmann, David Zweiker, Marie Muthspiel, Benjamin Panzer, Bernhard Jäger, Miklos Rohla, Kurt Huber. Low-density lipoprotein cholesterol reduction with immediate combination therapy of statin and ezetimibe compared to statin monotherapy after percutaneous coronary intervention.
Wiener klinische Wochenschrift.
2023 Dec; 135(23-24):674-679. doi:
10.1007/s00508-023-02296-z. [PMID: 37874347] - Julia Brandts, Sascha R Tittel, Peter Bramlage, Thomas Danne, Johanna M Brix, Stefan Zimny, Christoph H J Heyer, Reinhard W Holl, Dirk Müller-Wieland. Low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol in type 1 diabetes and type 2 diabetes: Lipid goal attainment in a large German-Austrian diabetes registry.
Diabetes, obesity & metabolism.
2023 12; 25(12):3700-3708. doi:
10.1111/dom.15264. [PMID: 37694759] - Jing Gu, Andreas Kuznik, Peter Quon, Ankita Chauhan, Tupili S Sravya, Frederick J Raal. Modelling the potential long-term survival benefit of evinacumab treatment vs. standard of care in patients with homozygous familial hypercholesterolaemia.
European journal of preventive cardiology.
2023 11; 30(17):1874-1880. doi:
10.1093/eurjpc/zwad203. [PMID: 37314419] - Seung-Ah Lee, Soon Jun Hong, Jung-Hoon Sung, Kyung-Soo Kim, Seong Hwan Kim, Jin Man Cho, Sung Wan Chun, Sang Rok Lee, Chul Sik Kim, Tae Nyun Kim, Dae Hyeok Kim, Hwan-Cheol Park, Byung Jin Kim, Hyun-Sook Kim, Ji-Yong Choi, Young Joon Hong, Joong Wha Chung, Seong Bo Yoon, Sang-Hak Lee, Cheol Whan Lee. Effectiveness of low-intensity atorvastatin 5 mg and ezetimibe 10 mg combination therapy compared with moderate-intensity atorvastatin 10 mg monotherapy: A randomized, double-blinded, multi-center, phase III study.
Medicine.
2023 Nov; 102(47):e36122. doi:
10.1097/md.0000000000036122. [PMID: 38013289] - Chang-Jiang Deng, Ju Yan, Ying-Ying Zheng, Ting-Ting Wu, Ying Pan, Xian-Geng Hou, Si-Fan Wang, Subinur Sirajidin, Mikereyi Aimaitijiang, Xiang Xie. Effectiveness of lipid-lowering therapy on mortality and major adverse cardiovascular event outcomes in patients undergoing percutaneous coronary intervention: a network meta-analysis of randomised controlled trials.
BMJ open.
2023 11; 13(11):e070827. doi:
10.1136/bmjopen-2022-070827. [PMID: 37967998] - Ryuk Jun Kwon, Young Hye Cho, Eun Ju Park, Youngin Lee, Sae Rom Lee, Jung In Choi, Sang Yeoup Lee, Soo Min Son. Effect of Combination Therapy with Ezetimibe and Statins versus Statin Monotherapy on Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Medicina (Kaunas, Lithuania).
2023 Nov; 59(11):. doi:
10.3390/medicina59111980. [PMID: 38004029] - Carlos Escobar, Vivencio Barrios, Angel Cequier, Juan Cosin-Sales, Jose Seijas, Juan José Gómez Doblas, Vicente Arrarte, Jose Tuñon, Maciej Banach. Impact of the Spanish consensus for improving lipid control on patients admitted for an acute coronary syndrome.
Journal of clinical lipidology.
2023 Nov; 17(6):756-764. doi:
10.1016/j.jacl.2023.10.002. [PMID: 37838521] - M M Schreuder, S Hamkour, K E Siegers, K B Holven, A K Johansen, M A van de Ree, B Imholz, E Boersma, L Louters, M P Bogsrud, K Retterstøl, F L J Visseren, J E Roeters van Lennep, C Koopal. LDL cholesterol targets rarely achieved in familial hypercholesterolemia patients: A sex and gender-specific analysis.
Atherosclerosis.
2023 11; 384(?):117117. doi:
10.1016/j.atherosclerosis.2023.03.022. [PMID: 37080805] - Jun Sung Moon, Il Rae Park, Sang Soo Kim, Hye Soon Kim, Nam Hoon Kim, Sin Gon Kim, Seung Hyun Ko, Ji Hyun Lee, Inkyu Lee, Bo Kyeong Lee, Kyu Chang Won. The Efficacy and Safety of Moderate-Intensity Rosuvastatin with Ezetimibe versus High-Intensity Rosuvastatin in High Atherosclerotic Cardiovascular Disease Risk Patients with Type 2 Diabetes Mellitus: A Randomized, Multicenter, Open, Parallel, Phase 4 Study.
Diabetes & metabolism journal.
2023 11; 47(6):818-825. doi:
10.4093/dmj.2023.0171. [PMID: 38043782] - Katja Sibylle Mühlberg. [Update on lipid lowering therapy in peripheral artery disease].
Deutsche medizinische Wochenschrift (1946).
2023 11; 148(22):1406-1411. doi:
10.1055/a-1956-9891. [PMID: 37918423] - Hélène Singeisen, Frida Renström, Markus Laimer, Roger Lehmann, Stefan Bilz, Michael Brändle. An estimation of the consequences of reinforcing the 2016 and 2019 European Society of Cardiology/European Atherosclerosis Society guidelines on current lipid-lowering treatment in patients with type 2 diabetes in tertiary care-a SwissDiab study.
European journal of preventive cardiology.
2023 10; 30(14):1473-1481. doi:
10.1093/eurjpc/zwad178. [PMID: 37226890] - Yung-An Chua, Sukma Azureen Nazli, Azhari Rosman, Sazzli Shahlan Kasim, Khairul Shafiq Ibrahim, Ahmad Bakhtiar Md Radzi, Noor Alicezah Mohd Kasim, Hapizah Nawawi. Attainment of Low-Density Lipoprotein Cholesterol Targets and Prescribing Pattern of Lipid-Lowering Medications among Patients with Familial Hypercholesterolemia Attending Specialist Clinics.
Journal of atherosclerosis and thrombosis.
2023 Oct; 30(10):1317-1326. doi:
10.5551/jat.63389. [PMID: 36567112] - Nicolas Dugré, Adrienne J Lindblad, Danielle Perry, G Michael Allan, Émélie Braschi, Jamie Falk, Liesbeth Froentjes, Scott R Garrison, Jessica E M Kirkwood, Christina S Korownyk, James P McCormack, Samantha S Moe, Allison Paige, Jen Potter, Betsy S Thomas, Joey Ton, Jennifer Young, Justin Weresch, Michael R Kolber. Lipid-lowering therapies for cardiovascular disease prevention and management in primary care: PEER umbrella systematic review of systematic reviews.
Canadian family physician Medecin de famille canadien.
2023 Oct; 69(10):701-711. doi:
10.46747/cfp.6910701. [PMID: 37833094] - Larry B Goldstein, Peter P Toth, Jennifer L Dearborn-Tomazos, Robert P Giugliano, Benjamin J Hirsh, Jessica M Peña, Magdy H Selim, Daniel Woo. Aggressive LDL-C Lowering and the Brain: Impact on Risk for Dementia and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association.
Arteriosclerosis, thrombosis, and vascular biology.
2023 10; 43(10):e404-e442. doi:
10.1161/atv.0000000000000164. [PMID: 37706297] - Jinhua Jin, Liwen Shan, Manjun Wang, Lu Liu, Tian Xu, Duanbin Li, Zhezhe Chen, Xianglan Liu, Wenbin Zhang, Ya Li. Variability in Plasma Lipids Between Intensive Statin Therapy and Conventional-Dose Statins Combined with Ezetimibe Therapy in Patients with Coronary Atherosclerosis Disease.
International heart journal.
2023 Sep; 64(5):807-815. doi:
10.1536/ihj.23-125. [PMID: 37704407] - Joanna Lewek, Jacek Niedziela, Piotr Desperak, Krzysztof Dyrbuś, Tadeusz Osadnik, Piotr Jankowski, Adam Witkowski, Agata Bielecka-Dąbrowa, Dariusz Dudek, Marek Gierlotka, Mariusz Gąsior, Maciej Banach. Intensive Statin Therapy Versus Upfront Combination Therapy of Statin and Ezetimibe in Patients With Acute Coronary Syndrome: A Propensity Score Matching Analysis Based on the PL-ACS Data.
Journal of the American Heart Association.
2023 09; 12(18):e030414. doi:
10.1161/jaha.123.030414. [PMID: 37671618] - Nicola Ferri, Massimiliano Ruscica, Raul D Santos, Alberto Corsini. Fixed Combination for the Treatment of Dyslipidaemia.
Current atherosclerosis reports.
2023 Sep; ?(?):. doi:
10.1007/s11883-023-01142-x. [PMID: 37715044] - Barak Zafrir, Amir Aker, Ibrahim Naoum, Walid Saliba. Guideline-Directed Low-Density Lipoprotein Cholesterol Management After Acute Ischemic Stroke: Findings from a National Health Care Service.
The American journal of cardiology.
2023 09; 203(?):332-338. doi:
10.1016/j.amjcard.2023.07.032. [PMID: 37517128] - Eun Yi Oh, Chae Eun Haam, Sooyeon Choi, Seonhee Byeon, Soo-Kyoung Choi, Young-Ho Lee. Ezetimibe Induces Vasodilation in Rat Mesenteric Resistance Arteries through Inhibition of Extracellular Ca2+ Influx.
International journal of molecular sciences.
2023 Sep; 24(18):. doi:
10.3390/ijms241813992. [PMID: 37762296] - Seung-Jun Lee, Jung-Joon Cha, Woong Gil Choi, Wang-Soo Lee, Jin-Ok Jeong, Seonghoon Choi, Yoon-Haeng Cho, Woojung Park, Chang-Hwan Yoon, Yong-Joon Lee, Sung-Jin Hong, Chul-Min Ahn, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Soon Jun Hong, Jung-Sun Kim. Moderate-Intensity Statin With Ezetimibe Combination Therapy vs High-Intensity Statin Monotherapy in Patients at Very High Risk of Atherosclerotic Cardiovascular Disease: A Post Hoc Analysis From the RACING Randomized Clinical Trial.
JAMA cardiology.
2023 09; 8(9):853-858. doi:
10.1001/jamacardio.2023.2222. [PMID: 37531130] - Liling Guo, Shuping Zhao, Wang Zhao. The clinical effect of Xuezhikang combined with ezetimibe in the treatment of coronary heart disease in lipid-lowering treatment and its influence on blood lipid level.
Panminerva medica.
2023 09; 65(3):426-427. doi:
10.23736/s0031-0808.21.04624-3. [PMID: 34931509] - B Li, Y Li, W-Z Peng, Y-Q Liu, Z-S Xu, J-K Wen. Effect of Ezetimibe combined with Simvastatin in the treatment of coronary heart disease: a retrospective analysis.
European review for medical and pharmacological sciences.
2023 09; 27(17):8212-8217. doi:
10.26355/eurrev_202309_33581. [PMID: 37750649] - Juan Pedro-Botet, Núria Plana, José María Mostaza, Juan José Gómez-Doblas, María Rosa Fernández Olmo, Carlos Escobar Cervantes, José Luis Díaz-Díaz, Raquel Campuzano Ruiz, Pedro Valdivielso, Juan Cosín-Sales. Hypercholesterolaemia control in Spain: The same situation with different regional realities.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis.
2023 Sep; 35(5):219-225. doi:
10.1016/j.arteri.2023.04.001. [PMID: 37120368] - Umidakhon Makhmudova, Beasat Samadifar, Aurel Maloku, Pellumb Haxhikadrija, Jens-Arndt Geiling, Robert Römer, Bernward Lauer, Sven Möbius-Winkler, Sylvia Otto, P Christian Schulze, Oliver Weingärtner. Intensive lipid-lowering therapy for early achievement of guideline-recommended LDL-cholesterol levels in patients with ST-elevation myocardial infarction ('Jena auf Ziel').
Clinical research in cardiology : official journal of the German Cardiac Society.
2023 Sep; 112(9):1212-1219. doi:
10.1007/s00392-022-02147-3. [PMID: 36602598] - Siyu Zhu, Tehasi Wang, Qingyi Wang, Mengyu Du. Application of Atorvastatin Combined with Ezetimibe in Elderly Patients with Hypertension Combined with T2DM and Analysis of Significance of Changes in Serum Bilirubin Levels During Treatment.
Alternative therapies in health and medicine.
2023 Aug; ?(?):. doi:
. [PMID: 37632947] - Sonia Sawant, Nelson Wang. Under-representation of ethnic and regional minorities in lipid-lowering randomized clinical trials: a systematic review and meta-analysis.
European journal of preventive cardiology.
2023 08; 30(11):1120-1131. doi:
10.1093/eurjpc/zwad030. [PMID: 36748994] - Ann Marie Navar, Ahmed A Kolkailah, Anand Gupta, Kristin Khalaf Gillard, Marc K Israel, Yiqing Wang, Eric D Peterson. Gaps in Guideline-Based Lipid-Lowering Therapy for Secondary Prevention in the United States: A Retrospective Cohort Study of 322 153 Patients.
Circulation. Cardiovascular quality and outcomes.
2023 08; 16(8):533-543. doi:
10.1161/circoutcomes.122.009787. [PMID: 37529931] - Daniel Tobias Michaeli, Julia Caroline Michaeli, Tobias Boch, Thomas Michaeli. Cost-Effectiveness of Lipid-Lowering Therapies for Cardiovascular Prevention in Germany.
Cardiovascular drugs and therapy.
2023 08; 37(4):683-694. doi:
10.1007/s10557-021-07310-y. [PMID: 35015186] - Nick S Nurmohamed, Patrick M Moriarty, Erik Sg Stroes. Considerations for routinely testing for high lipoprotein(a).
Current opinion in lipidology.
2023 08; 34(4):174-179. doi:
10.1097/mol.0000000000000838. [PMID: 35942815] - Christopher P Kovach, Elise C Mesenbring, Prerna Gupta, Thomas J Glorioso, P Michael Ho, Stephen W Waldo, Gregory G Schwartz. Projected Outcomes of Optimized Statin and Ezetimibe Therapy in US Military Veterans with Coronary Artery Disease.
JAMA network open.
2023 08; 6(8):e2329066. doi:
10.1001/jamanetworkopen.2023.29066. [PMID: 37638630] - David Sinning, Ulf Landmesser. [Hypercholesterolemia and cardiovascular risk].
Deutsche medizinische Wochenschrift (1946).
2023 08; 148(16):1025-1032. doi:
10.1055/a-1932-6448. [PMID: 37541292] - Seung-Jun Lee, Jae Hong Joo, Sohee Park, Choongki Kim, Dong-Woo Choi, Sung-Jin Hong, Chul-Min Ahn, Jung-Sun Kim, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Yangsoo Jang, Chung-Mo Nam, Myeong-Ki Hong. Combination Lipid-Lowering Therapy in Patients Undergoing Percutaneous Coronary Intervention.
Journal of the American College of Cardiology.
2023 08; 82(5):401-410. doi:
10.1016/j.jacc.2023.05.042. [PMID: 37495276] - Daniel Tobias Michaeli, Julia Caroline Michaeli, Sebastian Albers, Tobias Boch, Thomas Michaeli. Established and Emerging Lipid-Lowering Drugs for Primary and Secondary Cardiovascular Prevention.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
2023 Jul; ?(?):. doi:
10.1007/s40256-023-00594-5. [PMID: 37486464] - Christie M Ballantyne, Marc Ditmarsch, John Jp Kastelein, Adam J Nelson, Douglas Kling, Andrew Hsieh, Danielle L Curcio, Kevin C Maki, Michael H Davidson, Stephen J Nicholls. Obicetrapib plus ezetimibe as an adjunct to high-intensity statin therapy: A randomized phase 2 trial.
Journal of clinical lipidology.
2023 Jul; 17(4):491-503. doi:
10.1016/j.jacl.2023.05.098. [PMID: 37277261] - David Pinsdorf, Daniel Messiha, Olga Petrikhovich, Mikail Bahar, Martin Steinmetz, Amir Abbas Mahabadi, Iryna Dykun, Julia Lortz, Tienush Rassaf, Christos Rammos. Differences in treatment strategies for LDL-cholesterol reduction in a university lipid clinic vs. standard care apart from the use of PCSK9 inhibitors.
Journal of clinical lipidology.
2023 Jul; 17(4):504-511. doi:
10.1016/j.jacl.2023.05.100. [PMID: 37271601] - Hermann Toplak, Aikaterini Bilitou, Hannes Alber, Johann Auer, Martin Clodi, Christoph Ebenbichler, Evelyn Fließer-Görzer, Carmen Gelsinger, Ursula Hanusch, Bernhard Ludvik, Thomas Maca, Andreas Schober, Reinhard Sock, Walter S Speidl, Thomas M Stulnig, Raimund Weitgasser, Andreas Zirlik, Marina Koch, Sebastian Wienerroither, Sorrel E Wolowacz, Françoise Diamand, Alberico L Catapano. Simulation of bempedoic acid and ezetimibe in the lipid-lowering treatment pathway in Austria using the contemporary SANTORINI cohort of high and very high risk patients.
Wiener klinische Wochenschrift.
2023 Jul; 135(13-14):364-374. doi:
10.1007/s00508-023-02221-4. [PMID: 37286910] - Weiyi Shen, Wentao Shao, Qihan Wang, Bo Wang, Gang Zhao, Aihua Gu, Zhaoyan Jiang, Hai Hu. Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice.
Journal of biomedical science.
2023 Jun; 30(1):44. doi:
10.1186/s12929-023-00933-3. [PMID: 37370162] - Julia L Newton, Joseph Hamed, Helen Williams, Matt Kearney, Alison M Metcalfe, Gary A Ford. Optimizing lipid management-impact of the COVID 19 pandemic upon cardiovascular risk in England.
British medical bulletin.
2023 06; 146(1):19-26. doi:
10.1093/bmb/ldad009. [PMID: 37170945] - Jenny Nguy, Sarah A Hitchen, Nick S R Lan, Girish Dwivedi, Robert Larbalestier, Bu B Yeap, P Gerry Fegan. Barriers to prescribing proprotein convertase subtilisin-kexin type 9 inhibitors after coronary revascularisation.
Internal medicine journal.
2023 Jun; 53(6):994-1001. doi:
10.1111/imj.15700. [PMID: 35112773] - Pierre Sabouret, Etienne Puymirat, Serge Kownator, Kamel Abdennbi, Frédéric Lebeau, Michel Meltz, Denis Angoulvant, François Schiele. Lipid-lowering treatment up to one year after acute coronary syndrome: guidance from a French expert panel for the implementation of guidelines in practice.
Panminerva medica.
2023 Jun; 65(2):244-249. doi:
10.23736/s0031-0808.22.04777-2. [PMID: 36222543] - Juan Cosín-Sales, Raquel Campuzano Ruiz, José Luis Díaz Díaz, Carlos Escobar Cervantes, María Rosa Fernández Olmo, Juan José Gómez-Doblas, José María Mostaza, Juan Pedro-Botet, Núria Plana Gil, Pedro Valdivielso. Impact of physician's perception about LDL cholesterol control in clinical practice when treating patients in Spain.
Atherosclerosis.
2023 06; 375(?):38-44. doi:
10.1016/j.atherosclerosis.2023.04.013. [PMID: 37245425] - Avishay Elis. Current and future options in cholesterol lowering treatments.
European journal of internal medicine.
2023 06; 112(?):1-5. doi:
10.1016/j.ejim.2023.02.010. [PMID: 36813611] - V N Larina, T N Mironova, V G Larin, U V Makhova, D A Orlov, Yu Yu Varlamova, O V Kladovikova. [Current approaches to the treatment of patients with dyslipidemia in the real practice in the outpatient stage].
Kardiologiia.
2023 May; 63(4):11-15. doi:
10.18087/cardio.2023.4.n2396. [PMID: 37165989] - Claudio Bilato, Pasquale Caldarola, Giuseppe Musumeci, Furio Colivicchi. [Managing lipid risk in acute coronary syndrome patients in the real world: results from the BEST consensus].
Giornale italiano di cardiologia (2006).
2023 May; 24(5):383-390. doi:
10.1714/4026.40013. [PMID: 37102352] - Corey K Bradley, Ahmed A Kolkailah, Nishant P Shah, Courtney B Page, Eric D Peterson, Ann Marie Navar. Uptake of non-statin lipid-lowering therapies for secondary prevention in community practice.
Journal of clinical lipidology.
2023 May; 17(3):412-414. doi:
10.1016/j.jacl.2023.03.006. [PMID: 37029056] - Dong Yun Kim, Kyu Sik Chung, Jun Yong Park, Heon Yung Gee. Preventive effect of empagliflozin and ezetimibe on hepatic steatosis in adults and murine models.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 May; 161(?):114445. doi:
10.1016/j.biopha.2023.114445. [PMID: 36842353] - Yoonkyung Chang, Soojeong Eom, Minjeong Kim, Tae-Jin Song. Medical Management of Dyslipidemia for Secondary Stroke Prevention: Narrative Review.
Medicina (Kaunas, Lithuania).
2023 Apr; 59(4):. doi:
10.3390/medicina59040776. [PMID: 37109734] - Sang-Hyup Lee, Yong-Joon Lee, Jung Ho Heo, Seung-Ho Hur, Hyun Hee Choi, Kyung-Jin Kim, Ju Han Kim, Keun-Ho Park, Jung Hee Lee, Yu Jeong Choi, Seung-Jun Lee, Sung-Jin Hong, Chul-Min Ahn, Byeong-Keuk Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang, Jung-Sun Kim. Combination Moderate-Intensity Statin and Ezetimibe Therapy for Elderly Patients With Atherosclerosis.
Journal of the American College of Cardiology.
2023 04; 81(14):1339-1349. doi:
10.1016/j.jacc.2023.02.007. [PMID: 37019580] - Clara François, A M Willems, L Van Calster, E Germonpré, Johan De Sutter. Changes in lipid lowering medication and lipid levels over time in patients with stable coronary artery disease.
Acta clinica Belgica.
2023 Apr; 78(2):135-139. doi:
10.1080/17843286.2022.2084948. [PMID: 35695418] - Michael G Nanna, Adam J Nelson, Kevin Haynes, Sonali Shambhu, Zubin Eapen, Mark J Cziraky, Sara B Calvert, Neha J Pagidipati, Christopher B Granger. Lipid-lowering treatment among older patients with atherosclerotic cardiovascular disease.
Journal of the American Geriatrics Society.
2023 04; 71(4):1243-1249. doi:
10.1111/jgs.18172. [PMID: 36538393] - Clara Marquina, Jedidiah Morton, Ella Zomer, Stella Talic, Sean Lybrand, David Thomson, Danny Liew, Zanfina Ademi. Lost Therapeutic Benefit of Delayed Low-Density Lipoprotein Cholesterol Control in Statin-Treated Patients and Cost-Effectiveness Analysis of Lipid-Lowering Intensification.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.
2023 04; 26(4):498-507. doi:
10.1016/j.jval.2022.11.013. [PMID: 36442832] - Ahlia Sekkarie, Soyoun Park, Nicole L Therrien, Sandra L Jackson, Rebecca C Woodruff, Sharon Attipoe-Dorcoo, Peter K Yang, Laurence Sperling, Fleetwood Loustalot, Angela M Thompson-Paul. Trends in Lipid-Lowering Prescriptions: Increasing Use of Guideline-Concordant Pharmacotherapies, U.S., 2017‒2022.
American journal of preventive medicine.
2023 04; 64(4):561-566. doi:
10.1016/j.amepre.2022.10.010. [PMID: 36464556] - Hironobu Mitani, Kota Suzuki, Junya Ako, Kazuma Iekushi, Renata Majewska, Salsabil Touzeni, Shizuya Yamashita. Achievement Rates for Low-Density Lipoprotein Cholesterol Goals in Patients at High Risk of Atherosclerotic Cardiovascular Disease in a Real-World Setting in Japan.
Journal of atherosclerosis and thrombosis.
2023 Mar; ?(?):. doi:
10.5551/jat.63940. [PMID: 36928267] - Walter Oliver, Robert P Giugliano. Benefit of Combination Ezetimibe/Simvastatin Among High-Risk Populations: Lessons from the IMPROVE-IT Trial.
Current atherosclerosis reports.
2023 03; 25(3):85-93. doi:
10.1007/s11883-023-01084-4. [PMID: 36763180] - Juwon Kim, Danbee Kang, Hyejeong Park, Minwoong Kang, Ki Hong Choi, Taek Kyu Park, Joo Myung Lee, Jeong Hoon Yang, Young Bin Song, Jin-Ho Choi, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Eliseo Guallar, Juhee Cho, Joo-Yong Hahn. Moderate-Intensity Statins Plus Ezetimibe vs. High-Intensity Statins After Coronary Revascularization: A Cohort Study.
Cardiovascular drugs and therapy.
2023 02; 37(1):141-150. doi:
10.1007/s10557-021-07256-1. [PMID: 34533691] - Emily C McKinley, Vera A Bittner, Todd M Brown, Ligong Chen, Jason Exter, Michael E Farkouh, Lei Huang, Elizabeth A Jackson, Emily B Levitan, Kate K Orroth, Stephanie R Reading, Robert S Rosenson, Monika M Safford, Mark Woodward, Paul Muntner, Lisandro D Colantonio. The Projected Impact of Population-Wide Achievement of LDL Cholesterol <70 mg/dL on the Number of Recurrent Events Among US Adults with ASCVD.
Cardiovascular drugs and therapy.
2023 02; 37(1):107-116. doi:
10.1007/s10557-021-07268-x. [PMID: 34599698] - Salil Deo, Peter Ueda, Adil Muhammad Sheikh, Salah Altarabsheh, Yakov Elgudin, Joseph Rubelowsky, Brian Cmolik, Neil Hawkins, David McAllister, Marc Ruel, Naveed Sattar, Jill Pell. Lipid Lowering in 'Very High Risk' Patients Undergoing Coronary Artery Bypass Surgery and Its Projected Reduction in Risk for Recurrent Vascular Events: A Monte Carlo Stepwise Simulation Approach.
Journal of cardiovascular pharmacology.
2023 02; 81(2):120-128. doi:
10.1097/fjc.0000000000001374. [PMID: 36315474] - Guoyi Yang, C Mary Schooling. Statins, Type 2 Diabetes, and Body Mass Index: A Univariable and Multivariable Mendelian Randomization Study.
The Journal of clinical endocrinology and metabolism.
2023 01; 108(2):385-396. doi:
10.1210/clinem/dgac562. [PMID: 36184662] - Martina Aeschbacher-Germann, Nathalie Kaiser, Alexandre Speierer, Manuel R Blum, Douglas C Bauer, Cinzia Del Giovane, Drahomir Aujesky, Baris Gencer, Nicolas Rodondi, Elisavet Moutzouri. Lipid-Lowering Trials Are Not Representative of Patients Managed in Clinical Practice: A Systematic Review and Meta-Analysis of Exclusion Criteria.
Journal of the American Heart Association.
2023 01; 12(1):e026551. doi:
10.1161/jaha.122.026551. [PMID: 36565207] - Junko Tomida, Tsugumichi Sato, Tomoji Yoshida, Shoichi Senda, Akira Nakatsuma, Naomi Iihara. Statin, Ezetimibe, or Fibrate Initiation and Subsequent Use for the Primary and Secondary Prevention of Cardiovascular Diseases among Japanese Patients Aged ≥55 Years: A Nationwide Cohort Study.
Biological & pharmaceutical bulletin.
2023; 46(11):1548-1557. doi:
10.1248/bpb.b23-00336. [PMID: 37914357] - Nadeem Qureshi, Sotiris Antoniou, Jan H Cornel, Francois Schiele, Pasquale Perrone-Filardi, Johannes Brachmann, Eduard Sidelnikov, Guillermo Villa, Samara Ferguson, Christina Rowlands, José R González-Juanatey. European Physician Survey Characterizing the Clinical Pathway and Treatment Patterns of Patients Post-Myocardial Infarction.
Advances in therapy.
2023 Jan; 40(1):233-251. doi:
10.1007/s12325-022-02344-6. [PMID: 36289145] - Ewelina Woźniak, Marlena Broncel, Mateusz Niedzielski, Agnieszka Woźniak, Paulina Gorzelak-Pabiś. The effect of lipid-lowering therapies on the pro-inflammatory and anti-inflammatory properties of vascular endothelial cells.
PloS one.
2023; 18(2):e0280741. doi:
10.1371/journal.pone.0280741. [PMID: 36753488] - Pierre Vladimir Ennezat, Raphaëlle-Ashley Guerbaai, Sylvestre Maréchaux, Thierry H Le Jemtel, Patrice François. Extent of Low-density Lipoprotein Cholesterol Reduction and All-cause and Cardiovascular Mortality Benefit: A Systematic Review and Meta-analysis.
Journal of cardiovascular pharmacology.
2023 01; 81(1):35-44. doi:
10.1097/fjc.0000000000001345. [PMID: 36027598]
