Exact Mass: 397.0926

Exact Mass Matches: 397.0926

Found 1 metabolites which its exact mass value is equals to given mass value 397.0926, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

1-[(4-Phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione

1-[(4-Phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione

C22H14F3NO3 (397.0926)


VU 0365114 is a selective mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM, and >30 μM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human β-cells[1][2][3].