Exact Mass: 397.0926

Exact Mass Matches: 397.0926

Found 1 metabolites which its exact mass value is equals to given mass value 397.0926, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

1-[(4-Phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione

1-[(4-Phenylphenyl)methyl]-5-(trifluoromethoxy)indole-2,3-dione

C22H14F3NO3 (397.0926)


VU 0365114 is a selective mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM, and >30 μM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human β-cells[1][2][3].