Exact Mass: 387.0018618

Exact Mass Matches: 387.0018618

Found 1 metabolites which its exact mass value is equals to given mass value 387.0018618, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

ERK5-IN-2

ERK5-IN-2

C17H11BrFN3O2 (387.0018618)


ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis[1].