Exact Mass: 387.0018618

Exact Mass Matches: 387.0018618

Found 1 metabolites which its exact mass value is equals to given mass value 387.0018618, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

ERK5-IN-2

ERK5-IN-2

C17H11BrFN3O2 (387.0018618)


ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis[1].