Exact Mass: 383.1818

Exact Mass Matches: 383.1818

Found 172 metabolites which its exact mass value is equals to given mass value 383.1818, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Dihydrozeatin-O-glucoside

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2S)-2-methyl-4-[(3H-purin-6-yl)amino]butoxy]oxane-3,4,5-triol

C16H25N5O6 (383.1805)


Dihydrozeatin-O-glucoside belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. Fatty acyl glycosides of mono- and disaccharides are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol, a phosphorylated alcohol (phosphoprenol), or a hydroxy fatty acid, or to one carboxyl group of a fatty acid (ester linkage) or an amino alcohol. Dihydrozeatin-O-glucoside is an extremely weak basic (essentially neutral) compound (based on its pKa). Dihydrozeatin-O-glucoside is the product of the O-glucosylation of dihydrozeatin in the cytokinin O-glucosylation. The O-glucosylation is reversible and resistant to beta-glucosidases. This reaction only shuts the physiological activity of the molecule temporarily, and is a way to store a molecule. A human metabolite taken as a putative food compound of mammalian origin [HMDB]. Dihydrozeatin-O-glucoside is found in many foods, some of which are tarragon, swede, mamey sapote, and oil-seed camellia.

   

Deoxyaureothin

Deoxyaureothin

C22H25NO5 (383.1733)


A 4-pyranone that is 2-methoxy-3,5-dimethyl-4H-pyran-4-one which is substituted at position 6 by a 2,4-dimethyl-1-(p-nitrophenyl)hexa-1,3-dien-6-yl group (the E,E isomer).

   

Sacubitrilat

Sacubitrilat

C22H25NO5 (383.1733)


C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent

   

Dihydrozeatin-9-N-glucoside

(2R,3R,4S,5S,6R)-2-(6-{[(3S)-4-hydroxy-3-methylbutyl]amino}-9H-purin-9-yl)-6-(hydroxymethyl)oxane-3,4,5-triol

C16H25N5O6 (383.1805)


Dihydrozeatin-9-N-glucoside belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Dihydrozeatin-9-N-glucoside is possibly neutral. Dihydrozeatin-9-N-glucoside is involved in cytokinin 9-N-glucoside biosynthesis and is also involved in cytokinin-O-glucoside biosynthesis as a precursor to dihydrozeatin-9-N-glucoside-O-glucoside. N-Glucosylation at the 9-position is similar to the N-glucosylation at the 7-position. A human metabolite taken as a putative food compound of mammalian origin [HMDB]. Dihydrozeatin-9-N-glucoside is found in many foods, some of which are tronchuda cabbage, pear, persian lime, and turmeric.

   

Dihydrozeatin-7-N-glucoside

(2R,3R,4S,5S,6R)-2-(6-{[(3S)-4-hydroxy-3-methylbutyl]amino}-7H-purin-7-yl)-6-(hydroxymethyl)oxane-3,4,5-triol

C16H25N5O6 (383.1805)


Dihydrozeatin-7-N-glucoside (CAS: 91599-03-0) belongs to the class of organic compounds known as glycosylamines. Glycosylamines are compounds consisting of an amine with a beta-N-glycosidic bond to a carbohydrate, thus forming a cyclic hemiaminal ether bond (alpha-amino ether). Dihydrozeatin-7-N-glucoside is a strong basic compound (based on its pKa). Dihydrozeatin-7-N-glucoside is involved in cytokinin 7-N glucoside biosynthesis in plants as a product of the N-glucosylation of dihydrozeatin by UDP-glucose. When plants are exposed to a high concentration of cytokinins many are conjugated into 7-N glucosides. The addition to the N position decreases the physiological activity of the cytokine. Therefore, N-glucosylation may be a strategy of detoxification for plants. N-Glucosylation is common in radish.

   

Sacubitrilat

5-{[1,1-biphenyl]-4-yl}-4-[(3-carboxy-1-hydroxypropylidene)amino]-2-methylpentanoate

C22H25NO5 (383.1733)


   

N'-[2-(Oxidanylcarbamoyl)phenyl]-N-phenyl-octanediamide

N-[2-(dihydroxycarbonimidoyl)phenyl]-N-phenyloctanediimidate

C21H25N3O4 (383.1845)


   

Dihydrozeatin O-beta-D-Glucoside

2-(hydroxymethyl)-6-{2-methyl-4-[(7H-purin-6-yl)amino]butoxy}oxane-3,4,5-triol

C16H25N5O6 (383.1805)


Dihydrozeatin o-beta-d-glucoside is a member of the class of compounds known as fatty acyl glycosides of mono- and disaccharides. Fatty acyl glycosides of mono- and disaccharides are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol or of a phosphorylated alcohol (phosphoprenols), a hydroxy fatty acid or to one carboxyl group of a fatty acid (ester linkage) or to an amino alcohol. Dihydrozeatin o-beta-d-glucoside is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). Dihydrozeatin o-beta-d-glucoside can be found in soy bean, which makes dihydrozeatin o-beta-d-glucoside a potential biomarker for the consumption of this food product.

   

SCHEMBL13131860

SCHEMBL13131860

C22H25NO5 (383.1733)


   

Dehydrothalicsimidine

Dehydrothalicsimidine

C22H25NO5 (383.1733)


   

Antibiotic BN 186B

Antibiotic BN 186B

C14H29N3O9 (383.1904)


   
   

(+)-trans-Erioaustralasine

(+)-trans-Erioaustralasine

C22H25NO5 (383.1733)


   

Chlorolissoclimide

Chlorolissoclimide

C20H30ClNO4 (383.1863)


   
   
   

N,N-Dimethyl-2-(1,2,3-trimethoxynaphtho(2,1-f)(1,3)benzodioxol-4-yl)ethanamine

N,N-Dimethyl-2-(1,2,3-trimethoxynaphtho(2,1-f)(1,3)benzodioxol-4-yl)ethanamine

C22H25NO5 (383.1733)


   

Dihydrozeatin O-glucoside

Dihydrozeatin O-glucoside

C16H25N5O6 (383.1805)


   
   

2-(2,3-Dimethoxyphenyl)-5,8-dimethoxy-3-propyl-4(1H)-quinolinone

2-(2,3-Dimethoxyphenyl)-5,8-dimethoxy-3-propyl-4(1H)-quinolinone

C22H25NO5 (383.1733)


   

SCHEMBL15444611

SCHEMBL15444611

C22H25NO5 (383.1733)


   
   

3,4-dimethoxy-6,13-dimethyl-5,7,8,15-tetrahydro-6H-benzo[c][1,3]dioxolo[4,5:4,5]benzo[1,2-g]azecin-14-one

3,4-dimethoxy-6,13-dimethyl-5,7,8,15-tetrahydro-6H-benzo[c][1,3]dioxolo[4,5:4,5]benzo[1,2-g]azecin-14-one

C22H25NO5 (383.1733)


   

daphnicyclidin C

daphnicyclidin C

C22H25NO5 (383.1733)


   
   

(+/-)-raddeanamine

(+/-)-raddeanamine

C22H25NO5 (383.1733)


   

scaevodimerine A

scaevodimerine A

C21H25N3O4 (383.1845)


   

(+/-)-Corycavidine

(+/-)-Corycavidine

C22H25NO5 (383.1733)


   

5,8-dimethoxy-2-(3,4-dimethoxyphenyl)-3-propyl-1h-quinolin-4-one

5,8-dimethoxy-2-(3,4-dimethoxyphenyl)-3-propyl-1h-quinolin-4-one

C22H25NO5 (383.1733)


   

(7Xi,8S)-8,6,7-trimethoxy-2-methyl-6,8,3,4-tetrahydro-2H-spiro[indeno[4,5-d][1,3]dioxole-7,1-isoquinoline]|Fumaritrin

(7Xi,8S)-8,6,7-trimethoxy-2-methyl-6,8,3,4-tetrahydro-2H-spiro[indeno[4,5-d][1,3]dioxole-7,1-isoquinoline]|Fumaritrin

C22H25NO5 (383.1733)


   

Me glycoside,N,4-O-dibenzoyl-beta-L-Pyranose-3-Amino-2,3,6-trideoxy-3-C-methyl-xylo-hexose

Me glycoside,N,4-O-dibenzoyl-beta-L-Pyranose-3-Amino-2,3,6-trideoxy-3-C-methyl-xylo-hexose

C22H25NO5 (383.1733)


   

Antibiotic LL-AM 31gammar

Antibiotic LL-AM 31gammar

C14H29N3O9 (383.1904)


   

N-[2-(7-Hydroxy-3,4,6-trimethoxyphenanthren-1-yl)ethyl]-N-methylacetamide

N-[2-(7-Hydroxy-3,4,6-trimethoxyphenanthren-1-yl)ethyl]-N-methylacetamide

C22H25NO5 (383.1733)


   
   

Me glycoside,N,4-dibenzoyl-alpha-L-Pyranose-3-Amino-2,3,6-trideoxy-3-C-methyl-xylo-hexose

Me glycoside,N,4-dibenzoyl-alpha-L-Pyranose-3-Amino-2,3,6-trideoxy-3-C-methyl-xylo-hexose

C22H25NO5 (383.1733)


   
   
   
   
   
   
   
   
   
   
   
   
   
   
   

Dehydrocorydaline (hydroxyl)

Dehydrocorydaline (hydroxyl)

C22H25NO5 (383.1733)


   

dihydrozeatin-9-b-D-glucoside

dihydrozeatin-9-b-D-glucoside

C16H25N5O6 (383.1805)


   

(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-3-carbaldehyde

(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-3-carbaldehyde

C22H25NO5 (383.1733)


relative retention time with respect to 9-anthracene Carboxylic Acid is 0.778 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.773

   

6,7-Dimethoxy-1-[2-(2,3,4-trimethoxy-phenyl)-vinyl]-3,4-dihydro-isoquinoline

"NCGC00160170-01!6,7-Dimethoxy-1-[2-(2,3,4-trimethoxy-phenyl)-vinyl]-3,4-dihydro-isoquinoline"

C22H25NO5 (383.1733)


   

Peniprequinolone_120176

Peniprequinolone_120176

C22H25NO5 (383.1733)


   

C22H25NO5_(3R,4R)-4,5-Dihydroxy-3-methoxy-4-(4-methoxyphenyl)-6-(3-methyl-2-buten-1-yl)-3,4-dihydro-2(1H)-quinolinone

NCGC00169912-03_C22H25NO5_(3R,4R)-4,5-Dihydroxy-3-methoxy-4-(4-methoxyphenyl)-6-(3-methyl-2-buten-1-yl)-3,4-dihydro-2(1H)-quinolinone

C22H25NO5 (383.1733)


   

peniprequinolone

peniprequinolone

C22H25NO5 (383.1733)


   

Gly Asn Pro Pro

(2S)-1-{[(2S)-1-[(2S)-2-(2-aminoacetamido)-3-carbamoylpropanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

C16H25N5O6 (383.1805)


   

Gly Pro Asn Pro

(2S)-1-[(2S)-2-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]formamido}-3-carbamoylpropanoyl]pyrrolidine-2-carboxylic acid

C16H25N5O6 (383.1805)


   

Gly Pro Pro Asn

(2S)-2-{[(2S)-1-{[(2S)-1-(2-aminoacetyl)pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}-3-carbamoylpropanoic acid

C16H25N5O6 (383.1805)


   
   
   
   

Asn Gly Pro Pro

(2S)-1-{[(2S)-1-{2-[(2S)-2-amino-3-carbamoylpropanamido]acetyl}pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carboxylic acid

C16H25N5O6 (383.1805)


   

Asn Pro Gly Pro

(2S)-1-(2-{[(2S)-1-[(2S)-2-amino-3-carbamoylpropanoyl]pyrrolidin-2-yl]formamido}acetyl)pyrrolidine-2-carboxylic acid

C16H25N5O6 (383.1805)


   

Asn Pro Pro Gly

2-{[(2S)-1-{[(2S)-1-[(2S)-2-amino-3-carbamoylpropanoyl]pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}acetic acid

C16H25N5O6 (383.1805)


   
   
   

Pro Gly Asn Pro

(2S)-1-[(2S)-3-carbamoyl-2-{2-[(2S)-pyrrolidin-2-ylformamido]acetamido}propanoyl]pyrrolidine-2-carboxylic acid

C16H25N5O6 (383.1805)


   

Pro Gly Pro Asn

(2S)-3-carbamoyl-2-{[(2S)-1-{2-[(2S)-pyrrolidin-2-ylformamido]acetyl}pyrrolidin-2-yl]formamido}propanoic acid

C16H25N5O6 (383.1805)


   

Pro Asn Gly Pro

(2S)-1-{2-[(2S)-3-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]acetyl}pyrrolidine-2-carboxylic acid

C16H25N5O6 (383.1805)


   

Pro Asn Pro Gly

2-{[(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-pyrrolidin-2-ylformamido]propanoyl]pyrrolidin-2-yl]formamido}acetic acid

C16H25N5O6 (383.1805)


   

Pro Pro Gly Asn

(2S)-3-carbamoyl-2-(2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}acetamido)propanoic acid

C16H25N5O6 (383.1805)


   

Pro Pro Asn Gly

2-[(2S)-3-carbamoyl-2-{[(2S)-1-{[(2S)-pyrrolidin-2-yl]carbonyl}pyrrolidin-2-yl]formamido}propanamido]acetic acid

C16H25N5O6 (383.1805)


   
   
   

Dihydrozeatin-7-N-dihydrozeatin

Dihydrozeatin-7-N-dihydrozeatin

C16H25N5O6 (383.1805)


   

Dihydrozeatin-9-N-glucoside

Dihydrozeatin-9-N-glucoside

C16H25N5O6 (383.1805)


   

Dihydrozeatin-O-glucoside

Dihydrozeatin-O-glucoside

C16H25N5O6 (383.1805)


   

N-Boc-4-[2-(4-Toluenesulfonyloxy)ethyl]piperidine

N-Boc-4-[2-(4-Toluenesulfonyloxy)ethyl]piperidine

C19H29NO5S (383.1766)


   

1-(diphenylmethyl)azetidin-3-yl 2-carbamimidoylacetate acetate

1-(diphenylmethyl)azetidin-3-yl 2-carbamimidoylacetate acetate

C21H25N3O4 (383.1845)


   

nalpha-fmoc-l-serine tert-butyl ester

nalpha-fmoc-l-serine tert-butyl ester

C22H25NO5 (383.1733)


   

FMOC-(2S,3S)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID

FMOC-(2S,3S)-3-AMINO-2-HYDROXY-5-METHYLHEXANOIC ACID

C22H25NO5 (383.1733)


   

1-(Diphenylmethyl)-3-azetidinyl 3,3-diaminoacrylate acetate (1:1)

1-(Diphenylmethyl)-3-azetidinyl 3,3-diaminoacrylate acetate (1:1)

C21H25N3O4 (383.1845)


   

Fmoc-Ser(tBu)-OH

Fmoc-Ser(tBu)-OH

C22H25NO5 (383.1733)


   

N-(1-(2-(1H-INDOL-3-YL)ETHYL)PIPERIDIN-4-YL)BENZAMIDE HYDROCHLORIDE

N-(1-(2-(1H-INDOL-3-YL)ETHYL)PIPERIDIN-4-YL)BENZAMIDE HYDROCHLORIDE

C22H26ClN3O (383.1764)


   

4-Cyanobiphenyl-4-hexylbenzoate

4-Cyanobiphenyl-4-hexylbenzoate

C26H25NO2 (383.1885)


   

Fmoc-D-Ser(tBu)-OH

Fmoc-D-Ser(tBu)-OH

C22H25NO5 (383.1733)


   

N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide

N-((1-(2-(tert-Butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide

C19H27ClFN3O2 (383.1776)


C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators C93038 - Cation Channel Blocker

   

L-Alanyl-L-phenylalanyl-L-phenylalanine

L-Alanyl-L-phenylalanyl-L-phenylalanine

C21H25N3O4 (383.1845)


   

(2s)-1-{[5-(1h-Indazol-5-Yl)pyridin-3-Yl]oxy}-3-[(7as)-7ah-Indol-3-Yl]propan-2-Amine

(2s)-1-{[5-(1h-Indazol-5-Yl)pyridin-3-Yl]oxy}-3-[(7as)-7ah-Indol-3-Yl]propan-2-Amine

C23H21N5O (383.1746)


   

dihydrozeatin-7-N-glucose

dihydrozeatin-7-N-glucose

C16H25N5O6 (383.1805)


   

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-2-methyl-4-(7H-purin-6-ylamino)butoxy]oxane-3,4,5-triol

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-2-methyl-4-(7H-purin-6-ylamino)butoxy]oxane-3,4,5-triol

C16H25N5O6 (383.1805)


   

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[6-[[(3S)-4-hydroxy-3-methylbutyl]amino]purin-9-yl]oxane-3,4,5-triol

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[6-[[(3S)-4-hydroxy-3-methylbutyl]amino]purin-9-yl]oxane-3,4,5-triol

C16H25N5O6 (383.1805)


   

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2S)-2-methyl-4-(7H-purin-6-ylamino)butoxy]oxane-3,4,5-triol

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2S)-2-methyl-4-(7H-purin-6-ylamino)butoxy]oxane-3,4,5-triol

C16H25N5O6 (383.1805)


   

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[6-[[(3S)-4-hydroxy-3-methylbutyl]amino]purin-9-yl]oxane-3,4,5-triol

(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[6-[[(3S)-4-hydroxy-3-methylbutyl]amino]purin-9-yl]oxane-3,4,5-triol

C16H25N5O6 (383.1805)


   

Dihydrozeatin O-beta-D-glucoside

Dihydrozeatin O-beta-D-glucoside

C16H25N5O6 (383.1805)


   

Dihydrozeatin-7-N-glucoside

Dihydrozeatin-7-N-glucoside

C16H25N5O6 (383.1805)


   

Torrubiellone D

Torrubiellone D

C22H25NO5 (383.1733)


A natural product found in Torrubiella species.

   

2-(1-Imidazolyl)-4-phenyl-6-(4-phenyl-1-piperazinyl)-1,3,5-triazine

2-(1-Imidazolyl)-4-phenyl-6-(4-phenyl-1-piperazinyl)-1,3,5-triazine

C22H21N7 (383.1858)


   

7-(Diethylaminomethyl)-1-(4-methoxyphenyl)-2-methyl-3-nitro-6-indolol

7-(Diethylaminomethyl)-1-(4-methoxyphenyl)-2-methyl-3-nitro-6-indolol

C21H25N3O4 (383.1845)


   

6,7-dimethoxy-1-[(E)-2-(2,3,4-trimethoxyphenyl)ethenyl]-3,4-dihydroisoquinoline

6,7-dimethoxy-1-[(E)-2-(2,3,4-trimethoxyphenyl)ethenyl]-3,4-dihydroisoquinoline

C22H25NO5 (383.1733)


   
   

1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(dimethylamino)methyl]-N-(3-phenylpropylideneamino)-4-triazolecarboxamide

1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(dimethylamino)methyl]-N-(3-phenylpropylideneamino)-4-triazolecarboxamide

C17H21N9O2 (383.1818)


   

N-(1-tert-butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide

N-(1-tert-butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide

C21H25N3O4 (383.1845)


   
   

N-[[(2R,3R,4R)-4-(hydroxymethyl)-1-(2-methoxy-1-oxoethyl)-3-phenyl-2-azetidinyl]methyl]-N-methyl-4-pyridinecarboxamide

N-[[(2R,3R,4R)-4-(hydroxymethyl)-1-(2-methoxy-1-oxoethyl)-3-phenyl-2-azetidinyl]methyl]-N-methyl-4-pyridinecarboxamide

C21H25N3O4 (383.1845)


   

N-[[(2R,3S,4S)-4-(hydroxymethyl)-1-(2-methoxy-1-oxoethyl)-3-phenyl-2-azetidinyl]methyl]-N-methyl-4-pyridinecarboxamide

N-[[(2R,3S,4S)-4-(hydroxymethyl)-1-(2-methoxy-1-oxoethyl)-3-phenyl-2-azetidinyl]methyl]-N-methyl-4-pyridinecarboxamide

C21H25N3O4 (383.1845)


   

N-[[(2S,3S,4S)-4-(hydroxymethyl)-1-(2-methoxy-1-oxoethyl)-3-phenyl-2-azetidinyl]methyl]-N-methyl-4-pyridinecarboxamide

N-[[(2S,3S,4S)-4-(hydroxymethyl)-1-(2-methoxy-1-oxoethyl)-3-phenyl-2-azetidinyl]methyl]-N-methyl-4-pyridinecarboxamide

C21H25N3O4 (383.1845)


   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   
   

7-(alpha-D-glucosyl)dihydrozeatin

7-(alpha-D-glucosyl)dihydrozeatin

C16H25N5O6 (383.1805)


An N-glycosyldihydrozeatin in which the glycosyl fragment is an alpha-D-glucopyranosyl residue located at position 7.

   
   

BAY1125976

BAY1125976

C23H21N5O (383.1746)


BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively.

   

Dehydrocorydaline (hydroxyl)

Dehydrocorydaline (hydroxyl)

C22H25NO5 (383.1733)


Dehydrocorydaline (13-Methylpalmatine) hydroxyl is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline hydroxyl elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline hydroxyl shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90\%) using P. falciparum 3D7 strain.

   

n-[(2s,3s,4s,5r,6r)-6-{[(2s,3s,4r,5s)-1,4-diamino-2,5,6-trihydroxyhexan-3-yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]ethanimidic acid

n-[(2s,3s,4s,5r,6r)-6-{[(2s,3s,4r,5s)-1,4-diamino-2,5,6-trihydroxyhexan-3-yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]ethanimidic acid

C14H29N3O9 (383.1904)


   

7-(hepta-1,3,5-trien-1-yl)-2,6,8-trioxatricyclo[5.3.1.0⁴,¹¹]undecan-4-yl 2-aminobenzoate

7-(hepta-1,3,5-trien-1-yl)-2,6,8-trioxatricyclo[5.3.1.0⁴,¹¹]undecan-4-yl 2-aminobenzoate

C22H25NO5 (383.1733)


   

(3s,4s)-3-methoxy-4-(4-methoxyphenyl)-6-(3-methylbut-2-en-1-yl)-3h-quinoline-2,4,5-triol

(3s,4s)-3-methoxy-4-(4-methoxyphenyl)-6-(3-methylbut-2-en-1-yl)-3h-quinoline-2,4,5-triol

C22H25NO5 (383.1733)


   

4-({2-imino-5-[(4-methoxyphenyl)methyl]-3-methyl-1h-imidazol-4-yl}methyl)-2,6-dimethoxyphenol

4-({2-imino-5-[(4-methoxyphenyl)methyl]-3-methyl-1h-imidazol-4-yl}methyl)-2,6-dimethoxyphenol

C21H25N3O4 (383.1845)


   

3-[2-(7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

3-[2-(7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl)-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

C20H30ClNO4 (383.1863)


   

1-hydroxy-3,5,6-trimethoxy-10-methyl-4-(3-methylbut-2-en-1-yl)acridin-9-one

1-hydroxy-3,5,6-trimethoxy-10-methyl-4-(3-methylbut-2-en-1-yl)acridin-9-one

C22H25NO5 (383.1733)


   

3-{[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

3-{[2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

C21H25N3O4 (383.1845)


   

dimethyl(2-{1,2,3-trimethoxy-9h-phenanthro[2,3-d][1,3]dioxol-4-yl}ethyl)amine

dimethyl(2-{1,2,3-trimethoxy-9h-phenanthro[2,3-d][1,3]dioxol-4-yl}ethyl)amine

C22H25NO5 (383.1733)


   

(1s,9r,14s)-15-hydroxy-2,11-dimethoxy-14-methyl-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.0¹,¹³.0³,⁸]hexadeca-3,5,7,10,15-pentaen-12-one

(1s,9r,14s)-15-hydroxy-2,11-dimethoxy-14-methyl-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.0¹,¹³.0³,⁸]hexadeca-3,5,7,10,15-pentaen-12-one

C21H25N3O4 (383.1845)


   
   

(1s,4s,7s,11r)-7-[(1e,3e,5e)-hepta-1,3,5-trien-1-yl]-2,6,8-trioxatricyclo[5.3.1.0⁴,¹¹]undecan-4-yl 2-aminobenzoate

(1s,4s,7s,11r)-7-[(1e,3e,5e)-hepta-1,3,5-trien-1-yl]-2,6,8-trioxatricyclo[5.3.1.0⁴,¹¹]undecan-4-yl 2-aminobenzoate

C22H25NO5 (383.1733)


   

n-[(3s,6r)-6-{[(2s,3s,4r,5s)-1,4-diamino-2,5,6-trihydroxyhexan-3-yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]ethanimidic acid

n-[(3s,6r)-6-{[(2s,3s,4r,5s)-1,4-diamino-2,5,6-trihydroxyhexan-3-yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]ethanimidic acid

C14H29N3O9 (383.1904)


   

(12s,16s,17s,19r,20s)-17,22-dihydroxy-16,20-dimethyl-4-oxa-14-azahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹²,²⁰.0¹⁴,¹⁹]docosa-1(22),2(7),8(21)-triene-3,9-dione

(12s,16s,17s,19r,20s)-17,22-dihydroxy-16,20-dimethyl-4-oxa-14-azahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹²,²⁰.0¹⁴,¹⁹]docosa-1(22),2(7),8(21)-triene-3,9-dione

C22H25NO5 (383.1733)


   

(6r,7r)-6',7'-dimethoxy-2',6-dimethyl-2,3',4',8-tetrahydrospiro[indeno[4,5-d][1,3]dioxole-7,1'-isoquinolin]-6-ol

(6r,7r)-6',7'-dimethoxy-2',6-dimethyl-2,3',4',8-tetrahydrospiro[indeno[4,5-d][1,3]dioxole-7,1'-isoquinolin]-6-ol

C22H25NO5 (383.1733)


   

4-[(2e,4e,6e)-8-ethyl-1,9-dihydroxynona-2,4,6-trien-1-ylidene]-5-hydroxy-2-[(4-hydroxyphenyl)methyl]-2h-pyrrol-3-one

4-[(2e,4e,6e)-8-ethyl-1,9-dihydroxynona-2,4,6-trien-1-ylidene]-5-hydroxy-2-[(4-hydroxyphenyl)methyl]-2h-pyrrol-3-one

C22H25NO5 (383.1733)


   

(4z)-4-[(2e,4e,6e)-8-ethyl-1,9-dihydroxynona-2,4,6-trien-1-ylidene]-5-hydroxy-2-[(4-hydroxyphenyl)methyl]-2h-pyrrol-3-one

(4z)-4-[(2e,4e,6e)-8-ethyl-1,9-dihydroxynona-2,4,6-trien-1-ylidene]-5-hydroxy-2-[(4-hydroxyphenyl)methyl]-2h-pyrrol-3-one

C22H25NO5 (383.1733)


   

2-(3,4-dimethoxyphenyl)-5,8-dimethoxy-3-propyl-1h-quinolin-4-one

2-(3,4-dimethoxyphenyl)-5,8-dimethoxy-3-propyl-1h-quinolin-4-one

C22H25NO5 (383.1733)


   

3-{[2,6-dihydroxy-3-(2-methylbut-3-en-2-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

3-{[2,6-dihydroxy-3-(2-methylbut-3-en-2-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

C21H25N3O4 (383.1845)


   

(4as,6s,7r,7as)-4-(methoxycarbonyl)-7-methyl-1h,2h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyridin-6-yl (1s)-1-methyl-1,2-dihydro-2,7-naphthyridine-4-carboxylate

(4as,6s,7r,7as)-4-(methoxycarbonyl)-7-methyl-1h,2h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyridin-6-yl (1s)-1-methyl-1,2-dihydro-2,7-naphthyridine-4-carboxylate

C21H25N3O4 (383.1845)


   

4-(methoxycarbonyl)-7-methyl-1h,2h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyridin-6-yl 1-methyl-1,2-dihydro-2,7-naphthyridine-4-carboxylate

4-(methoxycarbonyl)-7-methyl-1h,2h,4ah,5h,6h,7h,7ah-cyclopenta[c]pyridin-6-yl 1-methyl-1,2-dihydro-2,7-naphthyridine-4-carboxylate

C21H25N3O4 (383.1845)


   

2-[(3e,5e)-3,5-dimethyl-6-(4-nitrophenyl)hexa-3,5-dien-1-yl]-6-methoxy-3,5-dimethylpyran-4-one

2-[(3e,5e)-3,5-dimethyl-6-(4-nitrophenyl)hexa-3,5-dien-1-yl]-6-methoxy-3,5-dimethylpyran-4-one

C22H25NO5 (383.1733)


   

[(2s,3s,5r,8r)-5,9,9-trimethyl-19-oxo-4,10-dioxa-18-azapentacyclo[9.8.0.0²,⁸.0³,⁵.0¹²,¹⁷]nonadeca-1(11),12,14,16-tetraen-18-yl]methyl acetate

[(2s,3s,5r,8r)-5,9,9-trimethyl-19-oxo-4,10-dioxa-18-azapentacyclo[9.8.0.0²,⁸.0³,⁵.0¹²,¹⁷]nonadeca-1(11),12,14,16-tetraen-18-yl]methyl acetate

C22H25NO5 (383.1733)


   

6',7'-dimethoxy-2',6-dimethyl-2,3',4',8-tetrahydrospiro[indeno[4,5-d][1,3]dioxole-7,1'-isoquinolin]-6-ol

6',7'-dimethoxy-2',6-dimethyl-2,3',4',8-tetrahydrospiro[indeno[4,5-d][1,3]dioxole-7,1'-isoquinolin]-6-ol

C22H25NO5 (383.1733)


   

4-(8-ethyl-1,9-dihydroxynona-2,4,6-trien-1-ylidene)-5-hydroxy-2-[(4-hydroxyphenyl)methyl]-2h-pyrrol-3-one

4-(8-ethyl-1,9-dihydroxynona-2,4,6-trien-1-ylidene)-5-hydroxy-2-[(4-hydroxyphenyl)methyl]-2h-pyrrol-3-one

C22H25NO5 (383.1733)


   

(3r)-3-[(1s)-2-[(1r,3s,4as,7s,8ar)-7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

(3r)-3-[(1s)-2-[(1r,3s,4as,7s,8ar)-7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

C20H30ClNO4 (383.1863)


   

(12s,16r,17s,19r,20s)-17,22-dihydroxy-16,20-dimethyl-4-oxa-14-azahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹²,²⁰.0¹⁴,¹⁹]docosa-1(22),2(7),8(21)-triene-3,9-dione

(12s,16r,17s,19r,20s)-17,22-dihydroxy-16,20-dimethyl-4-oxa-14-azahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹²,²⁰.0¹⁴,¹⁹]docosa-1(22),2(7),8(21)-triene-3,9-dione

C22H25NO5 (383.1733)


   

(3r)-3-[(1s)-2-[(1r,3s,4as,7s,8as)-7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

(3r)-3-[(1s)-2-[(1r,3s,4as,7s,8as)-7-chloro-3-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

C20H30ClNO4 (383.1863)


   

tert-butyl 3-{[(3s,8as)-1-hydroxy-4-oxo-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-3-yl]methyl}indole-1-carboxylate

tert-butyl 3-{[(3s,8as)-1-hydroxy-4-oxo-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-3-yl]methyl}indole-1-carboxylate

C21H25N3O4 (383.1845)


   

6-({2-imino-5-[(4-methoxyphenyl)methyl]-3-methyl-1h-imidazol-4-yl}methyl)-2,3-dimethoxyphenol

6-({2-imino-5-[(4-methoxyphenyl)methyl]-3-methyl-1h-imidazol-4-yl}methyl)-2,3-dimethoxyphenol

C21H25N3O4 (383.1845)


   

(3s,8as)-3-{[(3s)-2,6-dihydroxy-3-(2-methylbut-3-en-2-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

(3s,8as)-3-{[(3s)-2,6-dihydroxy-3-(2-methylbut-3-en-2-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

C21H25N3O4 (383.1845)


   

(2s,3s,4r,5s,6r)-2-(hydroxymethyl)-6-({[(2r)-4-(3h-purin-6-ylamino)butan-2-yl]oxy}methyl)oxane-3,4,5-triol

(2s,3s,4r,5s,6r)-2-(hydroxymethyl)-6-({[(2r)-4-(3h-purin-6-ylamino)butan-2-yl]oxy}methyl)oxane-3,4,5-triol

C16H25N5O6 (383.1805)


   

4,5,14,15,16-pentamethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2(7),3,5,8,13,15-heptaene

4,5,14,15,16-pentamethoxy-10-methyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(17),2(7),3,5,8,13,15-heptaene

C22H25NO5 (383.1733)


   

15-hydroxy-2,11-dimethoxy-14-methyl-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.0¹,¹³.0³,⁸]hexadeca-3,5,7,10,15-pentaen-12-one

15-hydroxy-2,11-dimethoxy-14-methyl-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.0¹,¹³.0³,⁸]hexadeca-3,5,7,10,15-pentaen-12-one

C21H25N3O4 (383.1845)


   

17,22-dihydroxy-16,20-dimethyl-4-oxa-14-azahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹²,²⁰.0¹⁴,¹⁹]docosa-1(22),2(7),8(21)-triene-3,9-dione

17,22-dihydroxy-16,20-dimethyl-4-oxa-14-azahexacyclo[15.4.1.0²,⁷.0⁸,²¹.0¹²,²⁰.0¹⁴,¹⁹]docosa-1(22),2(7),8(21)-triene-3,9-dione

C22H25NO5 (383.1733)


   

3-methoxy-4-(4-methoxyphenyl)-6-(3-methylbut-2-en-1-yl)-3h-quinoline-2,4,5-triol

3-methoxy-4-(4-methoxyphenyl)-6-(3-methylbut-2-en-1-yl)-3h-quinoline-2,4,5-triol

C22H25NO5 (383.1733)


   

(3s,8as)-3-{[(3s)-2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

(3s,8as)-3-{[(3s)-2,6-dihydroxy-3-(3-methylbut-2-en-1-yl)indol-3-yl]methyl}-1-hydroxy-3h,6h,7h,8h,8ah-pyrrolo[1,2-a]pyrazin-4-one

C21H25N3O4 (383.1845)


   

(3r,4r)-3-methoxy-4-(4-methoxyphenyl)-6-(3-methylbut-2-en-1-yl)-3h-quinoline-2,4,5-triol

(3r,4r)-3-methoxy-4-(4-methoxyphenyl)-6-(3-methylbut-2-en-1-yl)-3h-quinoline-2,4,5-triol

C22H25NO5 (383.1733)


   

{5,9,9-trimethyl-19-oxo-4,10-dioxa-18-azapentacyclo[9.8.0.0²,⁸.0³,⁵.0¹²,¹⁷]nonadeca-1(11),12,14,16-tetraen-18-yl}methyl acetate

{5,9,9-trimethyl-19-oxo-4,10-dioxa-18-azapentacyclo[9.8.0.0²,⁸.0³,⁵.0¹²,¹⁷]nonadeca-1(11),12,14,16-tetraen-18-yl}methyl acetate

C22H25NO5 (383.1733)


   

(3r)-3-[(1s)-2-[(1s,4r,4as,7s,8ar)-7-chloro-4-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

(3r)-3-[(1s)-2-[(1s,4r,4as,7s,8ar)-7-chloro-4-hydroxy-5,5,8a-trimethyl-2-methylidene-hexahydro-1h-naphthalen-1-yl]-1-hydroxyethyl]-5-hydroxy-3,4-dihydropyrrol-2-one

C20H30ClNO4 (383.1863)


   

[(2s,3s,5r,8s)-5,9,9-trimethyl-19-oxo-4,10-dioxa-18-azapentacyclo[9.8.0.0²,⁸.0³,⁵.0¹²,¹⁷]nonadeca-1(11),12,14,16-tetraen-18-yl]methyl acetate

[(2s,3s,5r,8s)-5,9,9-trimethyl-19-oxo-4,10-dioxa-18-azapentacyclo[9.8.0.0²,⁸.0³,⁵.0¹²,¹⁷]nonadeca-1(11),12,14,16-tetraen-18-yl]methyl acetate

C22H25NO5 (383.1733)