Exact Mass: 379.32120280000004

Exact Mass Matches: 379.32120280000004

Found 58 metabolites which its exact mass value is equals to given mass value 379.32120280000004, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Leukotriene B4 ethanolamide

(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide

C22H37NO4 (379.27224420000005)


Leukotriene B4 ethanolamide is a synthetic agonist of leukotriene B4 (LTB4), that interacts with both leukotriene B4 receptors and Vanilloid TRPV1 receptors. Leukotriene B4 is the major metabolite in neutrophil polymorphonuclear leukocytes. Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO is LTA4 (leukotriene A4), which is enzymatically converted into either LTB4 (leukotriene B4) by LTA4 hydrolase or LTC4 (leukotriene C4) by LTC4 synthase. The regulation of leukotriene production occurs at various levels, including expression of 5-LO, translocation of 5-LO to the perinuclear region and phosphorylation to either enhance or inhibit the activity of 5-LO. Biologically active LTB4 is metabolized by w-oxidation carried out by specific cytochrome P450s (CYP4F) followed by beta-oxidation from the w-carboxy position and after CoA ester formation. Other specific pathways of leukotriene metabolism include the 12-hydroxydehydrogenase/ 15-oxo-prostaglandin-13-reductase that form a series of conjugated diene metabolites that have been observed to be excreted into human urine. Metabolism of LTC4 occurs by sequential peptide cleavage reactions involving a gamma-glutamyl transpeptidase that forms LTD4 (leukotriene D4) and a membrane-bound dipeptidase that converts LTD4 into LTE4 (leukotriene E4) before w-oxidation. These metabolic transformations of the primary leukotrienes are critical for termination of their biological activity, and defects in expression of participating enzymes may be involved in specific genetic disease. (PMID 17623009, 16207832)Leukotrienes are eicosanoids. The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs), leukotrienes (LTs), and lipoxins (LXs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes), and leukotrienes from leukocytes, hence the derivation of their names. All mammalian cells except erythrocytes synthesize eicosanoids. These molecules are extremely potent, able to cause profound physiological effects at very dilute concentrations. All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signalling pathways. Leukotriene B4 ethanolamide is a synthetic agonist of leukotriene B4 (LTB4), that interacts with both leukotriene B4 receptors and Vanilloid TRPV1 receptors. Leukotriene B4 is the major metabolite in neutrophil polymorphonuclear leukocytes. Leukotrienes are metabolites of arachidonic acid derived from the action of 5-LO (5-lipoxygenase). The immediate product of 5-LO is LTA4 (leukotriene A4), which is enzymatically converted into either LTB4 (leukotriene B4) by LTA4 hydrolase or LTC4 (leukotriene C4) by LTC4 synthase. The regulation of leukotriene production occurs at various levels, including expression of 5-LO, translocation of 5-LO to the perinuclear region and phosphorylation to either enhance or inhibit the activity of 5-LO. Biologically active LTB4 is metabolized by w-oxidation carried out by specific cytochrome P450s (CYP4F) followed by beta-oxidation from the w-carboxy position and after CoA ester formation. Other specific pathways of leukotriene metabolism include the 12-hydroxydehydrogenase/ 15-oxo-prostaglandin-13-reductase that form a series of conjugated diene metabolites that have been observed to be excreted into human urine. Metabolism of LTC4 occurs by sequential peptide cleavage reactions involving a gamma-glutamyl transpeptidase that forms LTD4 (leukotriene D4) and a membrane-bound dipeptidase that converts LTD4 into LTE4 (leukotriene E4) before w-oxidation. These metabolic transformations of the primary leukotrienes are critical for termination of their biological activity, and defects in expression of participating enzymes may be involved in specific genetic disease. (PMID 17623009, 16207832)

   

N-Linoleoyl Valine

2-[(1-Hydroxyoctadeca-9,12-dien-1-ylidene)amino]-3-methylbutanoate

C23H41NO3 (379.3086276)


N-linoleoyl valine belongs to the class of compounds known as N-acylamides. These are molecules characterized by a fatty acyl group linked to a primary amine by an amide bond. More specifically, it is a Linoleic acid amide of Valine. It is believed that there are more than 800 types of N-acylamides in the human body. N-acylamides fall into several categories: amino acid conjugates (e.g., those acyl amides conjugated with amino acids), neurotransmitter conjugates (e.g., those acylamides conjugated with neurotransmitters), ethanolamine conjugates (e.g., those acylamides conjugated to ethanolamine), and taurine conjugates (e.g., those acyamides conjugated to taurine). N-Linoleoyl Valine is an amino acid conjugate. N-acylamides can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain N-acylamides; 2) medium-chain N-acylamides; 3) long-chain N-acylamides; and 4) very long-chain N-acylamides; 5) hydroxy N-acylamides; 6) branched chain N-acylamides; 7) unsaturated N-acylamides; 8) dicarboxylic N-acylamides and 9) miscellaneous N-acylamides. N-Linoleoyl Valine is therefore classified as a long chain N-acylamide. N-acyl amides have a variety of signaling functions in physiology, including in cardiovascular activity, metabolic homeostasis, memory, cognition, pain, motor control and others (PMID: 15655504). N-acyl amides have also been shown to play a role in cell migration, inflammation and certain pathological conditions such as diabetes, cancer, neurodegenerative disease, and obesity (PMID: 23144998; PMID: 25136293; PMID: 28854168).N-acyl amides can be synthesized both endogenously and by gut microbiota (PMID: 28854168). N-acylamides can be biosynthesized via different routes, depending on the parent amine group. N-acyl ethanolamines (NAEs) are formed via the hydrolysis of an unusual phospholipid precursor, N-acyl-phosphatidylethanolamine (NAPE), by a specific phospholipase D. N-acyl amino acids are synthesized via a circulating peptidase M20 domain containing 1 (PM20D1), which can catalyze the bidirectional the condensation and hydrolysis of a variety of N-acyl amino acids. The degradation of N-acylamides is largely mediated by an enzyme called fatty acid amide hydrolase (FAAH), which catalyzes the hydrolysis of N-acylamides into fatty acids and the biogenic amines. Many N-acylamides are involved in lipid signaling system through interactions with transient receptor potential channels (TRP). TRP channel proteins interact with N-acyl amides such as N-arachidonoyl ethanolamide (Anandamide), N-arachidonoyl dopamine and others in an opportunistic fashion (PMID: 23178153). This signaling system has been shown to play a role in the physiological processes involved in inflammation (PMID: 25136293). Other N-acyl amides, including N-oleoyl-glutamine, have also been characterized as TRP channel antagonists (PMID: 29967167). N-acylamides have also been shown to have G-protein-coupled receptors (GPCRs) binding activity (PMID: 28854168). The study of N-acylamides is an active area of research and it is likely that many novel N-acylamides will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered for these molecules.

   

Homopseudopteroxazole

Homopseudopteroxazole

C26H37NO (379.2874992)


   
   

(+-)-Oncinotin|(+/-)-Oncinotin|(-)-oncinotine|(R)-(-)-oncinotine|(R)-8-(4-amino-butyl)-octadecahydro-4a,8-diaza-benzocycloheptadecen-9-one|(R)-Oncinotine|(??)-Oncinotine|Oncinotin|oncinotine

(+-)-Oncinotin|(+/-)-Oncinotin|(-)-oncinotine|(R)-(-)-oncinotine|(R)-8-(4-amino-butyl)-octadecahydro-4a,8-diaza-benzocycloheptadecen-9-one|(R)-Oncinotine|(??)-Oncinotine|Oncinotin|oncinotine

C23H45N3O (379.356244)


   
   

(()-Neooncinotine

(()-Neooncinotine

C23H45N3O (379.356244)


   
   
   

Solanida-3,5-dien|solanida-3,5-diene|Solanthrene

Solanida-3,5-dien|solanida-3,5-diene|Solanthrene

C27H41N (379.32388260000005)


   

(-)-isooncinotine|docosahydro-4a,9,13-triaza-benzocyclodocosen-14-one|Isooncinotin

(-)-isooncinotine|docosahydro-4a,9,13-triaza-benzocyclodocosen-14-one|Isooncinotin

C23H45N3O (379.356244)


   

(6Z,9Z,12Z,15Z)-1-(phenethylamino)octadeca-6,9,12,15-tetraen-3-one|(6Z,9Z,12Z,15Z)-1-[(2-phenylethyl)amino]octadeca-6,9,12,15-tetraen-3-one

(6Z,9Z,12Z,15Z)-1-(phenethylamino)octadeca-6,9,12,15-tetraen-3-one|(6Z,9Z,12Z,15Z)-1-[(2-phenylethyl)amino]octadeca-6,9,12,15-tetraen-3-one

C26H37NO (379.2874992)


   

Solanthren

(1S,2S,10R,11S,14S,15R,16S,17R,20S,23S)-10,14,16,20-tetramethyl-22-azahexacyclo[12.10.0.02,11.05,10.015,23.017,22]tetracosa-4,6-diene

C27H41N (379.32388260000005)


   

LTB4 ethanol amide

N-(2-hydroxyethyl)-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraen-1-amide

C22H37NO4 (379.27224420000005)


   
   

N-oleoyl proline

N-(9Z-octadecenoyl)-proline

C23H41NO3 (379.3086276)


   

N-linoleoyl valine

N-(9Z,12Z-octadecadienoyl)-valine

C23H41NO3 (379.3086276)


   

NA 23:3;O2

N-(9Z,12Z-octadecadienoyl)-valine

C23H41NO3 (379.3086276)


   

3O-C18:1-HSL

N-(3-oxo-11Z-octadecenoyl)-homoserine lactone

C22H37NO4 (379.27224420000005)


   
   

N,N,N-Tributyl-1-butanaminium salicylate

N,N,N-Tributyl-1-butanaminium salicylate

C23H41NO3 (379.3086276)


   

Lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride

Lithium tris[(3-ethyl-3-pentyl)oxy]aluminohydride

C21H45AlLiO3 (379.33439799999996)


   

(S)-3-cyclohexylpropyl 1-(3,3-diMethyl-2-oxopentanoyl)piperidine-2-carboxylate

(S)-3-cyclohexylpropyl 1-(3,3-diMethyl-2-oxopentanoyl)piperidine-2-carboxylate

C22H37NO4 (379.27224420000005)


   

N-(4-butylphenyl)-1-(4-nonoxyphenyl)methanimine

N-(4-butylphenyl)-1-(4-nonoxyphenyl)methanimine

C26H37NO (379.2874992)


   

3-(dodecenyl)-2,5-dioxo-1-Pyrrolidinehexanoic acid

3-(dodecenyl)-2,5-dioxo-1-Pyrrolidinehexanoic acid

C22H37NO4 (379.27224420000005)


   

N-[12-(1h-Imidazol-1-Yl)dodecanoyl]-L-Leucine

N-[12-(1h-Imidazol-1-Yl)dodecanoyl]-L-Leucine

C21H37N3O3 (379.2834772)


   
   
   
   
   

3-methyl-2-[[(9E,12E)-octadeca-9,12-dienoyl]amino]butanoic acid

3-methyl-2-[[(9E,12E)-octadeca-9,12-dienoyl]amino]butanoic acid

C23H41NO3 (379.3086276)


   

(13Z,16Z)-N-(2-hydroxyethyl)docosa-13,16-dienamide

(13Z,16Z)-N-(2-hydroxyethyl)docosa-13,16-dienamide

C24H45NO2 (379.345011)


   

N-[(4E,8E,12E)-1,3-dihydroxytetradeca-4,8,12-trien-2-yl]nonanamide

N-[(4E,8E,12E)-1,3-dihydroxytetradeca-4,8,12-trien-2-yl]nonanamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxypentadeca-4,8,12-trien-2-yl]octanamide

N-[(4E,8E,12E)-1,3-dihydroxypentadeca-4,8,12-trien-2-yl]octanamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxyoctadeca-4,8,12-trien-2-yl]pentanamide

N-[(4E,8E,12E)-1,3-dihydroxyoctadeca-4,8,12-trien-2-yl]pentanamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxyicosa-4,8,12-trien-2-yl]propanamide

N-[(4E,8E,12E)-1,3-dihydroxyicosa-4,8,12-trien-2-yl]propanamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxynonadeca-4,8,12-trien-2-yl]butanamide

N-[(4E,8E,12E)-1,3-dihydroxynonadeca-4,8,12-trien-2-yl]butanamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxyhenicosa-4,8,12-trien-2-yl]acetamide

N-[(4E,8E,12E)-1,3-dihydroxyhenicosa-4,8,12-trien-2-yl]acetamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxyheptadeca-4,8,12-trien-2-yl]hexanamide

N-[(4E,8E,12E)-1,3-dihydroxyheptadeca-4,8,12-trien-2-yl]hexanamide

C23H41NO3 (379.3086276)


   

N-[(4E,8E,12E)-1,3-dihydroxyhexadeca-4,8,12-trien-2-yl]heptanamide

N-[(4E,8E,12E)-1,3-dihydroxyhexadeca-4,8,12-trien-2-yl]heptanamide

C23H41NO3 (379.3086276)


   
   
   

N-(3-oxo-11Z-octadecenoyl)-homoserine lactone

N-(3-oxo-11Z-octadecenoyl)-homoserine lactone

C22H37NO4 (379.27224420000005)


   

pentacosenoate

pentacosenoate

C25H47O2 (379.35758619999996)


A monounsaturated fatty acid anion with a chain that is composed of 25 carbons and 1 double bond (position unspecified).

   

2-hydroxytetracosadienoate

2-hydroxytetracosadienoate

C24H43O3 (379.32120280000004)


A 2-hydroxy fatty acid anion with a chain that is composed of 24 carbons and 2 double bond (positions unspecified).

   

NA-Ala 20:2(11Z,14Z)

NA-Ala 20:2(11Z,14Z)

C23H41NO3 (379.3086276)


   
   

NA-Ile 17:2(9Z,12Z)

NA-Ile 17:2(9Z,12Z)

C23H41NO3 (379.3086276)


   

NA-Leu 17:2(9Z,12Z)

NA-Leu 17:2(9Z,12Z)

C23H41NO3 (379.3086276)


   
   
   

NA-Val 18:2(9E,12E)

NA-Val 18:2(9E,12E)

C23H41NO3 (379.3086276)


   

NA-Val 18:2(9Z,12Z)

NA-Val 18:2(9Z,12Z)

C23H41NO3 (379.3086276)


   
   

(21ar)-10-(3-aminopropyl)-octadecahydro-1h-pyrido[1,2-f]1,6-diazacyclooctadecan-11-one

(21ar)-10-(3-aminopropyl)-octadecahydro-1h-pyrido[1,2-f]1,6-diazacyclooctadecan-11-one

C23H45N3O (379.356244)


   

n-(4-{[3-({3-[(3-aminopropyl)amino]propyl}amino)propyl]amino}butyl)-4-hydroxybenzamide

n-(4-{[3-({3-[(3-aminopropyl)amino]propyl}amino)propyl]amino}butyl)-4-hydroxybenzamide

C20H37N5O2 (379.2947102)