Exact Mass: 377.30603940000003

Exact Mass Matches: 377.30603940000003

Found 79 metabolites which its exact mass value is equals to given mass value 377.30603940000003, within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error 0.01 dalton.

Karacoline

(1S,2R,3R,4S,5S,6S,8S,9S,13R,16S,17R)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8,16-triol

C22H35NO4 (377.25659500000006)

Karakoline is an organonitrogen heterocyclic compound that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methyl, and methoxy groups, respectively. It has a role as a phytotoxin. It is a tertiary amino compound, a tertiary alcohol, a secondary alcohol, an alkaloid, an organonitrogen heterocyclic compound and a bridged compound. It derives from a hydride of an aconitane. Carmicheline is a natural product found in Aconitum karakolicum, Euglena gracilis, and Aconitum carmichaelii with data available. Origin: Plant; Formula(Parent): C22H35NO4; Bottle Name:Karakoline hydrochloride; PRIME Parent Name:Karakoline; PRIME in-house No.:V0337; SubCategory_DNP: Terpenoid alkaloids, Diterpene alkaloid, Aconitum alkaloid

NCIOpen2_008730

6beta-(Dimethylamino)-3beta,5-dihydroxy-5alpha-pregnan-20-one

C23H39NO3 (377.29297840000004)

17-(Bis(2-hydroxyethyl)amino)androst-5-en-3-ol

17beta-[Bis(2-hydroxyethyl)amino]androst-5-en-3beta-ol

C23H39NO3 (377.29297840000004)

Arachidonoyl Serinol

(5Z,8Z,11Z,14Z)-N-(1,3-dihydroxypropan-2-yl)icosa-5,8,11,14-tetraenamide

C23H39NO3 (377.29297840000004)

2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor (PMID: 8954083, 9399597). Replacement of the sn-2 oxygen in the glycerol moiety of 2-AG with a nitrogen atom gives arachidonoyl serinol (PMID: 8893848). Arachidonoyl serinol is much more stable than 2-AG. However, it is at least a log less potent as a CB1 receptor agonist than 2-AG (PMID: 9399597). 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.1,2 Replacement of the sn-2 oxygen in the glycerol moiety of 2-AG with a nitrogen atom gives arachidonoyl serinol.3 Arachidonoyl serinol is much more stable than 2-AG. However, it is at least a log less potent as a CB1 receptor agonist than 2-AG. [HMDB]

N-Linoleoyl Proline

1-(octadeca-9,12-dienoyl)pyrrolidine-2-carboxylic acid

C23H39NO3 (377.29297840000004)

N-linoleoyl proline belongs to the class of compounds known as N-acylamides. These are molecules characterized by a fatty acyl group linked to a primary amine by an amide bond. More specifically, it is a Linoleic acid amide of Proline. It is believed that there are more than 800 types of N-acylamides in the human body. N-acylamides fall into several categories: amino acid conjugates (e.g., those acyl amides conjugated with amino acids), neurotransmitter conjugates (e.g., those acylamides conjugated with neurotransmitters), ethanolamine conjugates (e.g., those acylamides conjugated to ethanolamine), and taurine conjugates (e.g., those acyamides conjugated to taurine). N-Linoleoyl Proline is an amino acid conjugate. N-acylamides can be classified into 9 different categories depending on the size of their acyl-group: 1) short-chain N-acylamides; 2) medium-chain N-acylamides; 3) long-chain N-acylamides; and 4) very long-chain N-acylamides; 5) hydroxy N-acylamides; 6) branched chain N-acylamides; 7) unsaturated N-acylamides; 8) dicarboxylic N-acylamides and 9) miscellaneous N-acylamides. N-Linoleoyl Proline is therefore classified as a long chain N-acylamide. N-acyl amides have a variety of signaling functions in physiology, including in cardiovascular activity, metabolic homeostasis, memory, cognition, pain, motor control and others (PMID: 15655504). N-acyl amides have also been shown to play a role in cell migration, inflammation and certain pathological conditions such as diabetes, cancer, neurodegenerative disease, and obesity (PMID: 23144998; PMID: 25136293; PMID: 28854168).N-acyl amides can be synthesized both endogenously and by gut microbiota (PMID: 28854168). N-acylamides can be biosynthesized via different routes, depending on the parent amine group. N-acyl ethanolamines (NAEs) are formed via the hydrolysis of an unusual phospholipid precursor, N-acyl-phosphatidylethanolamine (NAPE), by a specific phospholipase D. N-acyl amino acids are synthesized via a circulating peptidase M20 domain containing 1 (PM20D1), which can catalyze the bidirectional the condensation and hydrolysis of a variety of N-acyl amino acids. The degradation of N-acylamides is largely mediated by an enzyme called fatty acid amide hydrolase (FAAH), which catalyzes the hydrolysis of N-acylamides into fatty acids and the biogenic amines. Many N-acylamides are involved in lipid signaling system through interactions with transient receptor potential channels (TRP). TRP channel proteins interact with N-acyl amides such as N-arachidonoyl ethanolamide (Anandamide), N-arachidonoyl dopamine and others in an opportunistic fashion (PMID: 23178153). This signaling system has been shown to play a role in the physiological processes involved in inflammation (PMID: 25136293). Other N-acyl amides, including N-oleoyl-glutamine, have also been characterized as TRP channel antagonists (PMID: 29967167). N-acylamides have also been shown to have G-protein-coupled receptors (GPCRs) binding activity (PMID: 28854168). The study of N-acylamides is an active area of research and it is likely that many novel N-acylamides will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered for these molecules.

Madangolide

C23H39NO3 (377.29297840000004)

Aconosine

C22H35NO4 (377.25659500000006)

Origin: Plant; SubCategory_DNP: Terpenoid alkaloids, Diterpene alkaloid, Aconitum alkaloid

Karakoline

(1S,2R,3R,4S,5S,6S,8S,9S,10S,13R,16S,17R)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8,16-triol

C22H35NO4 (377.25659500000006)

An organonitrogen heterocyclic compound that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methyl, and methoxy groups, respectively. Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.396 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.391

MLS002153956-01!Karakoline39089-30-0

C22H35NO4 (377.25659500000006)

AA dihydroxypropylamine

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(1,3-dihydroxy-propyl-2-amine)

C23H39NO3 (377.29297840000004)

15-HETE-Gly

N-(15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-glycine

C22H35NO4 (377.25659500000006)

12-HETE-Gly

N-(12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoyl)-glycine

C22H35NO4 (377.25659500000006)

NA 23:4;O2

N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(1,3-dihydroxy-propyl-2-amine)

C23H39NO3 (377.29297840000004)

NA 22:5;O3

N-(12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoyl)-glycine

C22H35NO4 (377.25659500000006)

NAT 17:0

N-heptadecanoyl taurine

C19H39NO4S (377.25996540000006)

Stieleriacine C

N-(dodecanoyl)-6-methyl-tyrosine

C22H35NO4 (377.25659500000006)

N-Ethyl-N,N-dimethyl-1-hexadecanaminium bromide

C20H44BrN (377.26569240000003)

Tetrabutylphosphonium benzotriazol-1-ide

C22H40N3P (377.29596900000007)

(2-hydroxyethyl)dimethyloctadecylammonium chloride

C22H48ClNO (377.3424228)

HEXADECANOIC ACID 2-NITROPHENYL ESTER

C22H35NO4 (377.25659500000006)

sodium N-methyl-N-(1-oxooctadecyl)aminoacetate

C21H40NNaO3 (377.2905730000001)

CDA

Ethylhexadecyldimethylammonium bromide

C20H44BrN (377.26569240000003)

N,N,N-Tripentyl-1-pentanaminium bromide

C20H44BrN (377.26569240000003)

(2-hexadecoxy-2-oxoethyl)-trimethylazanium,chloride

C21H44ClNO2 (377.30603940000003)

Sodium N-hexadecanoyl-L-valinate

C21H40NNaO3 (377.2905730000001)

4-Nitrophenyl palmitate

C22H35NO4 (377.25659500000006)

Triethanolamine myristate

2-[bis(2-hydroxyethyl)amino]ethanol,tetradecanoic acid

C20H43NO5 (377.31410680000005)

5-Tert-butyl-7-(4-ethyl-1-piperazinyl)-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine

C23H31N5 (377.2579326)

6beta-(Dimethylamino)-3beta,5-dihydroxy-5alpha-pregnan-20-one

C23H39NO3 (377.29297840000004)

N-Linoleoyl Proline

C23H39NO3 (377.29297840000004)

17beta-[Bis(2-hydroxyethyl)amino]androst-5-en-3beta-ol

C23H39NO3 (377.29297840000004)

1-[2-Hydroxy-3-[4-(2-methylbutan-2-yl)phenoxy]propyl]-4-piperidinecarboxylic acid ethyl ester

C22H35NO4 (377.25659500000006)

(1S,2R,3R,5S,6S,8S,9S,13R,16S,17R)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8,16-triol

C22H35NO4 (377.25659500000006)

(10Z,13Z,16Z)-N-(2-hydroxyethyl)docosa-10,13,16-trienamide

C24H43NO2 (377.3293618)

(1alpha,5xi,9xi,10xi,14alpha)-20-Ethyl-1,16-dimethoxyaconitane-8,14-diol

C22H35NO4 (377.25659500000006)

N-arachidonoyl dihydroxypropylamine

C23H39NO3 (377.29297840000004)

SPHP(19:1)

SPHP(m19:1)

C19H40NO4P (377.2694810000001)

NA-Ala 20:3(8Z,11Z,14Z)

C23H39NO3 (377.29297840000004)

NA-Dopamine 15:0

C23H39NO3 (377.29297840000004)

NA-His 15:1(9Z)

C21H35N3O3 (377.267828)

NA-Histamine 18:0

C23H43N3O (377.3405948)

NA-Taurine 17:0

C19H39NO4S (377.25996540000006)

NA-Thr 18:4(6Z,9Z,12Z,15Z)

C22H35NO4 (377.25659500000006)

NA-Tyr 13:0

C22H35NO4 (377.25659500000006)

NA-Val 18:3(6Z,9Z,12Z)

C23H39NO3 (377.29297840000004)

NA-Val 18:3(9Z,12Z,15Z)

C23H39NO3 (377.29297840000004)

ST 20:1;O2;Gly

C22H35NO4 (377.25659500000006)

(5s,6s,8s,10r,13r)-11-ethyl-6,16-dimethoxy-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,8-diol

C22H35NO4 (377.25659500000006)

(1r,2s,5r,8r,9r,10r,11s,12r,13s,15r,16r)-7-ethyl-12-(hydroxymethyl)-5-methyl-7-azahexacyclo[7.6.2.2¹⁰,¹³.0¹,⁸.0⁵,¹⁶.0¹⁰,¹⁵]nonadecane-2,11,12-triol

C22H35NO4 (377.25659500000006)

(1s,2r,3r,4s,5s,6s,8s,9s,10r,13r,16s,17r)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,8,16-triol

C22H35NO4 (377.25659500000006)

11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,8,16-triol

C22H35NO4 (377.25659500000006)

(1s,2r,3r,4s,5s,6s,8s,9s,10r,13s,16s,17r)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.1²,⁵.0¹,¹⁰.0³,⁸.0¹³,¹⁷]nonadecane-4,8,16-triol

C22H35NO4 (377.25659500000006)

alginine

C23H39NO3 (377.29297840000004)

{"Ingredient_id": "HBIN015127","Ingredient_name": "alginine","Alias": "NA","Ingredient_formula": "C23H39NO3","Ingredient_Smile": "NA","Ingredient_weight": "377.566","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7038","PubChem_id": "NA","DrugBank_id": "NA"}