Exact Mass: 377.11756379999997
Exact Mass Matches: 377.11756379999997
Found 57 metabolites which its exact mass value is equals to given mass value 377.11756379999997,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
6-(2-Hydroxyethyl)-5,6-dihydrosanguinarine
C22H19NO5 (377.12631640000006)
JNJ-38877605
C19H13F2N7 (377.12004420000005)
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C164000 - c-Met-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
S-(2-Hydroxy-3-buten-1-yl)glutathione
(2S)-2-(Butanoylamino)-5-[[(1R)-2-(carboxymethylamino)-2-oxo-1-(sulfanylmethyl)ethyl]amino]-5-oxo-pentanoic acid
Ethoxysanguinarine
C22H19NO5 (377.12631640000006)
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1]. Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine is an inhibitor of protein phosphatase 2A (CIP2A). Ethoxysanguinarine induces cell apoptosis and inhibits colorectal cancer cells growth[1].
Piscerythoxazole
C22H19NO5 (377.12631640000006)
L-gamma-glutamyl-S-3-(1-oxobutyl)-L-cysteinyl-glycine
This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 16HP2005 to the Mass Spectrometry Society of Japan.
O1-(2-acetylamino-[1]naphthyl)-beta-D-glucopyranuronic acid|O1-(2-Acetylamino-[1]naphthyl)-beta-D-glucopyranuronsaeure
4-methoxyfuro[2,3-b]quinolin-7-yl beta-D-mannopyranoside|dictamnine-7-beta-D-mannopyranoside
(2-hydroxy-1-methoxy-12-methyl-12,13-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c]phenanthridin-13-yl)-acetaldehyde|11-(Formyl-methylenyl)-O-desmethyl-dihydrochelerythrin
C22H19NO5 (377.12631640000006)
O1-(6-acetylamino-[2]naphthyl)-beta-D-glucopyranuronic acid|O1-(6-Acetylamino-[2]naphthyl)-beta-D-glucopyranuronsaeure
14-Ethoxy-13-methyl-13,14-dihydro-[1,3]dioxolo[4,5:4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine
C22H19NO5 (377.12631640000006)
3-[[2-(4-phenylmethoxyphenoxy)acetyl]amino]benzoic acid
C22H19NO5 (377.12631640000006)
disperse blue 124
C16H19N5O4S (377.11576940000003)
5-(4-TERT-BUTYLPHENYL)-4-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLE-3-THIOL
C19H18F3N3S (377.11734640000003)
CH5132799
C15H19N7O3S (377.12700240000004)
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C2152 - Phosphatidylinositide 3-Kinase Inhibitor C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor
1,2-di-o-acetyl-3-azido-3-deoxy-5-o-toluoyl-d-ribofuranose
Selurampanel
C16H19N5O4S (377.11576940000003)
C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent
Ethyl 6-fluoro-1-methyl-4-oxo-7-(1-piprazinyl)-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylate
C18H20FN3O3S (377.1209342000001)
4-[[2-methoxy-4-[(4-nitrophenyl)azo]phenyl]azo]phenol
C19H15N5O4 (377.11239900000004)
Dasolampanel
C17H20ClN5O3 (377.1254600000001)
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
N-(2-methoxydibenzofuran-3-yl)-2-(4-methoxyphenoxy)acetamide
C22H19NO5 (377.12631640000006)
2-[(2-methyl-4-benzofuro[3,2-d]pyrimidinyl)thio]-N-(2-phenylethyl)acetamide
C21H19N3O2S (377.11979140000005)
3,4-Dimethyl-6-(6-nitro-1,3-benzodioxol-5-yl)-2-oxo-1,6-dihydropyrimidine-5-carboxylic acid propyl ester
N2-phenyl-6-[[(1-phenyl-5-tetrazolyl)thio]methyl]-1,3,5-triazine-2,4-diamine
C17H15N9S (377.11710700000003)
N-ethyl-8-methyl-4-oxo-N-(phenylmethyl)-2-thieno[3,2-c][1]benzopyrancarboxamide
C22H19NO3S (377.1085584000001)
3-(4-methylphenyl)-5-oxo-N-propyl-8-thiazolo[2,3-b]quinazolinecarboxamide
C21H19N3O2S (377.11979140000005)
(2S)-2-[[(2-chlorophenyl)-oxomethyl]amino]-3-methylbutanoic acid (3-cyano-4-imino-2-oxopentyl) ester
C18H20ClN3O4 (377.1142270000001)
4,7-DI(Para-ethoxyphenyl)-1,2,5-thiadiazolo(3,4-C)pyridine
C21H19N3O2S (377.11979140000005)
CBiPES
C21H19N3O2S (377.11979140000005)
CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases[1][2].
CCT128930 (hydrochloride)
CCT128930 hydrochloride is a potent and selective inhibitor of AKT (IC50=6 nM). CCT128930 hydrochloride has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). CCT128930 hydrochloride induces cell cycle arrest, DNA damage, and autophagy. Antitumor activity[1][2].
mGluR2 antagonist 1
C21H16FN3O3 (377.11756379999997)
mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability[1].
MLS-573151
C21H19N3O2S (377.11979140000005)
MLS-573151 (MLS000573151) is a selective GTPase Cdc42 inhibitor with an EC50 of 2 μM. MLS-573151 is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42[1][2].
(2s,3r,4r,5r,6s)-2-({6-[(z)-(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
2-[(23s)-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-23-yl]ethanol
C22H19NO5 (377.12631640000006)
(2r,3r,4s,5s,6r)-2-({6-[(z)-(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
methyl 3-{4-acetyl-5-hydroxy-8-methylphenanthro[3,4-d][1,3]oxazol-2-yl}propanoate
C22H19NO5 (377.12631640000006)
2-({6-[(hydroxyimino)methyl]-[2,2'-bipyridin]-3-yl}oxy)-6-methyloxane-3,4,5-triol
2-(hydroxymethyl)-6-({4-methoxyfuro[2,3-b]quinolin-7-yl}oxy)oxane-3,4,5-triol
7-(diethylamino)-3-(5-phenyl-1,3,4-thiadiazol-2-yl)chromen-2-one
C21H19N3O2S (377.11979140000005)
(2r,3s,4s,5s,6s)-2-(hydroxymethyl)-6-({4-methoxyfuro[2,3-b]quinolin-7-yl}oxy)oxane-3,4,5-triol
7-hydroxy-3-[4-methoxy-7-(3-methylbut-2-en-1-yl)-1,3-benzoxazol-6-yl]chromen-4-one
C22H19NO5 (377.12631640000006)
11'-hydroxy-2-(2-hydroxyethyl)-7-methoxy-6'-methyl-3'-oxaspiro[isoindole-1,2'-tricyclo[6.3.1.0⁴,¹²]dodecane]-1'(12'),4',6',8',10'-pentaen-3-one
C22H19NO5 (377.12631640000006)
(3r,6r)-3-(1h-indol-3-ylmethyl)-6-isopropyl-3,6-bis(methylsulfanyl)pyrazine-2,5-diol
2-{24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0²,¹⁰.0⁴,⁸.0¹⁴,²².0¹⁷,²¹]tetracosa-1(13),2,4(8),9,11,14,16,21-octaen-23-yl}ethanol
C22H19NO5 (377.12631640000006)