Exact Mass: 358.1659
Exact Mass Matches: 358.1659
Found 75 metabolites which its exact mass value is equals to given mass value 358.1659,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Cilastatin
(Z)-7-((R)-2-Amino-2-carboxy-ethylsulphanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, imipenem, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. [PubChem] D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors C471 - Enzyme Inhibitor > C783 - Protease Inhibitor CONFIDENCE standard compound; INTERNAL_ID 2129
7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]-oxomethyl]amino]-2-heptenoic acid
7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]-oxomethyl]amino]-2-heptenoic acid
4-[(3S)-3-hydroxybutyl]-2-methoxyphenyl-beta-D-glucopyranoside|bumaldoside C
4-[(3S)-3-hydroxybutyl]-2-methoxyphenyl-beta-D-glucopyranoside|bumaldoside C
1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3-hydroxy-3-methylbutyl)benzene
1-O-beta-glucopyranosyl-1,4-dihydroxy-2-(3-hydroxy-3-methylbutyl)benzene
Cilastatin
7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid
The thioether resulting from the formal oxidative coupling of the thiol group of L-cysteine with the 7-position of (2Z)-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin is therefore administered (as the sodium salt) with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to inactive and potentially nephrotoxic products. Cilastatin also acts as a leukotriene D4 dipeptidase inhibitor, preventing the metabolism of leukotriene D4 to leukotriene E4. D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors C471 - Enzyme Inhibitor > C783 - Protease Inhibitor CONFIDENCE standard compound; INTERNAL_ID 2129 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2555 EAWAG_UCHEM_ID 2555; CONFIDENCE standard compound
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione,2-ethyl-2-(hydroxymethyl)propane-1,3-diol,prop-2-enoic acid
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione,2-ethyl-2-(hydroxymethyl)propane-1,3-diol,prop-2-enoic acid
(2R,3S,4R,5R)-2-(Aminomethyl)-5-(6-(benzylamino)-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol
(2R,3S,4R,5R)-2-(Aminomethyl)-5-(6-(benzylamino)-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol
tert-Butyl 4-(5-nitroquinolin-8-yl)piperazine-1-carboxylate
tert-Butyl 4-(5-nitroquinolin-8-yl)piperazine-1-carboxylate
ethyl (3S)-3-[[4-(4-carbamimidoylanilino)-4-oxobutanoyl]amino]pent-4-ynoate
ethyl (3S)-3-[[4-(4-carbamimidoylanilino)-4-oxobutanoyl]amino]pent-4-ynoate
N-{3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}propanamide hydrochloride (1:1)
N-{3-Acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}propanamide hydrochloride (1:1)
tert-Butyl 4-(5-nitroquinolin-6-yl)piperazine-1-carboxylate
tert-Butyl 4-(5-nitroquinolin-6-yl)piperazine-1-carboxylate
7-((2-Amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl)carbonyl)amino)-2-heptenoic acid
7-((2-Amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl)carbonyl)amino)-2-heptenoic acid
N-(4-phenoxyphenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide
N-(4-phenoxyphenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide
N-[2-[2-[2-[[oxo(3-pyridinyl)methyl]amino]ethoxy]ethoxy]ethyl]-3-pyridinecarboxamide
N-[2-[2-[2-[[oxo(3-pyridinyl)methyl]amino]ethoxy]ethoxy]ethyl]-3-pyridinecarboxamide
(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)ammonium hydrogen maleate
(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)ammonium hydrogen maleate
4-[(4-Ethoxy-3-methoxyphenyl)-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one
4-[(4-Ethoxy-3-methoxyphenyl)-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one
3,5-dimethyl-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide
3,5-dimethyl-N-[4-[(1-oxo-2-phenylethyl)amino]phenyl]benzamide
N-[(2-furanylmethylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamide
N-[(2-furanylmethylamino)-oxomethyl]-2-[4-(4-hydroxyphenyl)-1-piperazinyl]acetamide
3-[2-(4-fluorophenyl)-4-quinolinyl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine
3-[2-(4-fluorophenyl)-4-quinolinyl]-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine
N-[[(2R,3S,4R)-3-[4-(2-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2R,3S,4R)-3-[4-(2-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3R,4S)-3-[4-(2-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3R,4S)-3-[4-(2-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3S,4S)-3-[4-(2-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-methoxyacetamide
N-[[(2S,3S,4S)-3-[4-(2-fluorophenyl)phenyl]-4-(hydroxymethyl)-2-azetidinyl]methyl]-2-methoxyacetamide
N-[(E)-(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylideneamino]-3-(4-propan-2-yloxyphenyl)propanamide
N-[(E)-(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylideneamino]-3-(4-propan-2-yloxyphenyl)propanamide
2,3-Dihydroxypropyl (2-hydroxy-3-octoxypropyl) hydrogen phosphate
2,3-Dihydroxypropyl (2-hydroxy-3-octoxypropyl) hydrogen phosphate
(2s,3r,4s,5s,6r)-2-{4-[(3s)-3-hydroxybutyl]-2-methoxyphenoxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-{4-[(3s)-3-hydroxybutyl]-2-methoxyphenoxy}-6-(hydroxymethyl)oxane-3,4,5-triol
4,4,7a-trimethyl-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6,7-dihydro-5h-1-benzofuran-2-one
4,4,7a-trimethyl-6-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6,7-dihydro-5h-1-benzofuran-2-one
2-[4-hydroxy-2-(3-hydroxy-3-methylbutyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2-[4-hydroxy-2-(3-hydroxy-3-methylbutyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2-[4-(3-hydroxybutyl)-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2-[4-(3-hydroxybutyl)-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-[3-hydroxy-5-(5-hydroxypentyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-[3-hydroxy-5-(5-hydroxypentyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(5s)-5-[(s)-hydroxy(3-hydroxy-4-methoxyphenyl)methyl]-6,6-dimethyl-2h,5h,7h,8h-[1,3]dioxolo[4,5-g]isoquinolin-6-ium
(5s)-5-[(s)-hydroxy(3-hydroxy-4-methoxyphenyl)methyl]-6,6-dimethyl-2h,5h,7h,8h-[1,3]dioxolo[4,5-g]isoquinolin-6-ium
3-[1,3-dihydroxy-1-(2-methylpropyl)-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]propanimidic acid
3-[1,3-dihydroxy-1-(2-methylpropyl)-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]propanimidic acid
(6s,7ar)-4,4,7a-trimethyl-6-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6,7-dihydro-5h-1-benzofuran-2-one
(6s,7ar)-4,4,7a-trimethyl-6-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6,7-dihydro-5h-1-benzofuran-2-one
3-[(1r,4s)-1,3-dihydroxy-1-(2-methylpropyl)-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]propanimidic acid
3-[(1r,4s)-1,3-dihydroxy-1-(2-methylpropyl)-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]propanimidic acid
5-[hydroxy(3-hydroxy-4-methoxyphenyl)methyl]-6,6-dimethyl-2h,5h,7h,8h-[1,3]dioxolo[4,5-g]isoquinolin-6-ium
5-[hydroxy(3-hydroxy-4-methoxyphenyl)methyl]-6,6-dimethyl-2h,5h,7h,8h-[1,3]dioxolo[4,5-g]isoquinolin-6-ium
3,14,16-trihydroxy-5,15-dimethoxy-10,10-dimethyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2,4,6,13(17),14-hexaen-10-ium
3,14,16-trihydroxy-5,15-dimethoxy-10,10-dimethyl-10-azatetracyclo[7.7.1.0²,⁷.0¹³,¹⁷]heptadeca-1(16),2,4,6,13(17),14-hexaen-10-ium
(6r,7ar)-4,4,7a-trimethyl-6-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6,7-dihydro-5h-1-benzofuran-2-one
(6r,7ar)-4,4,7a-trimethyl-6-{[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6,7-dihydro-5h-1-benzofuran-2-one
2-[3-hydroxy-5-(5-hydroxypentyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2-[3-hydroxy-5-(5-hydroxypentyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2z)-7-{[(2r)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1s)-2,2-dimethylcyclopropyl](hydroxy)methylidene}amino)hept-2-enoic acid
(2z)-7-{[(2r)-2-amino-2-carboxyethyl]sulfanyl}-2-({[(1s)-2,2-dimethylcyclopropyl](hydroxy)methylidene}amino)hept-2-enoic acid
(2s,3r,4s,5s,6r)-2-[4-hydroxy-2-(3-hydroxy-3-methylbutyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-[4-hydroxy-2-(3-hydroxy-3-methylbutyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
3-[(1r,4s)-1-tert-butyl-1,3-dihydroxy-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]propanimidic acid
3-[(1r,4s)-1-tert-butyl-1,3-dihydroxy-6-oxo-4h-pyrazino[2,1-b]quinazolin-4-yl]propanimidic acid
